Nerve agents are molecular weapons that invade the body and sabotage part of the nervous system, causing horrific symptoms and sometimes death within minutes. Few antidotes exist, and those that do must be administered soon after an attack. But now scientists report in the journal ACS Nano an early-stage development of a potential treatment that soldiers or others could take before such agents are unleashed.

One particular antidote, an enzyme called organophosphorus acid anhydrolase (OPAA), has attracted attention recently for its ability to break down nerve agents. But the body’s immune system gets rid of it quickly. Packaging the enzyme in liposome nanocarriers gives the antidote greater staying power, but handling and storing the liposomes is complicated. So Omar K. Farha and colleagues wanted to make a potentially simpler carrier.

For a material, the researchers turned to porous metal-organic frameworks (MOFs), a class of hybrid materials made of metallic ions and organic ligands that are easy to store and handle at room temperature. They used a zirconium-based MOF and loaded it with the antidote. Testing showed the MOF-encapsulated enzyme was even more effective at breaking down the nerve agent simulant diisopropyl fluorophosphate and the nerve agent soman than the antidote by itself.

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Nice read.

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When square CSRR cells were cascaded (Fig. 12), a compact SIW circuit was achieved with bandpass response, with low return and insertion losses from 7.2 to 10.0 GHz. This compact bandpass filter has dimensions of 34 × 18 mm² and is formed from three cascaded CSRR cells. It was simulated from 4 to 10 GHz with simulated results of −33.1-dB minimum return loss and 0.3-DB insertion loss at 8.8 GHz (Fig. 13).

The miniature CSRR-loaded SIW bandpass filter shows reasonable insertion and return losses from 7.2 to 9.8 GHz. This technology, of fabricating CSRR cells with SIW transmission lines on low-loss microwave substrate materials, shows great promise for the creation of compact bandpass filters at microwave frequencies.

Dr. Benmostefa Naima, Researcher

New phase-change materials make permanent storage up to a thousand times faster.

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Awesome @ my friends at ORNL! Luv it and expect much success too.

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No one knows what the next, best way to build electronic circuits will be. That said there’s no shortage of efforts to invent something beyond current lithography. Oak Ridge National Laboratory, perhaps not surprisingly, is in the thick of the race and two recent studies from ORNL researchers showcase promising but very different approaches.

One method suggests phase change in a single complex oxide material may allow “creating” circuit elements much smaller than in today’s CMOS process while a second study puts STEM (scanning transmission electron microscopy) to work directly writing tiny patterns in metallic “ink,” forming features in liquid that are finer than half the width of a human hair. Articles describing both are posted on the ORNL web site.

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Advancing efforts around Synthetic Bio into the semiconductor space.

“We hope that ongoing advances in our method may lead to the development of new organic electronic devices, including semiconductor and luminescent materials,” say Segawa and Itam.

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Thiophene-fused polycyclic aromatic hydrocarbons (PAHs) are known to be useful as organic semiconductors due to their high charge transport properties. Scientists have developed a short route to form various thiophene-fused PAHs by simply heating mono-functionalized PAHs with sulfur. This new method is expected to contribute towards the efficient development of novel thiophene-based electronic materials.

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Spider silk is well-known for its unusual combination of being both lightweight and extremely strong—in some cases, stronger than steel. Due to these properties, researchers have been developing spider-silk-inspired materials for potential applications such as durable yet lightweight clothing, bullet-proof vests, and parachutes.

But so far, the acoustic properties of spider webs have not yet been explored. Now in a new study, a team of researchers from Italy, France and the UK has designed an acoustic metamaterial (which is a material made of periodically repeating structures) influenced by the intricate spider web architecture of the golden silk orb-weaver, also called the Nephila spider.

“There has been much work in the field of metamaterials in recent years to find the most efficient configurations for wave attenuation and manipulation,” coauthor Federico Bosia, a physicist at the University of Torino in Italy, told Phys.org. “We have found that the spider web architecture, combined with the variable elastic properties of radial and circumferential silk, is capable of attenuating and absorbing vibrations in wide frequency ranges, despite being lightweight.”

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