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Category: life extension – Page 37
In most vertebrates, a pattern of chemical marks on the genome is a reliable indicator of age, but in axolotls this clock seems to stop after the first four years of life.
Last week we reported that The Cat Health Company had closed its pre-seed round and is now moving towards identifying and developing new therapeutics for age-related diseases in cats. As the pet longevity field continues to gather momentum, The Cat Health Company aims to join companies like Loyal and Arterra at the forefront of this movement. Founded by Alex Bacita and Alex Voda, the Bucharest-based company is not only focused on improving the lifespan of our feline friends but also on enhancing their overall quality of life by targeting the underlying mechanisms of aging.
Longevity. Technology: Pet longevity is becoming a growing area of interest for both researchers and consumers; as owners increasingly seek solutions to extend the healthspan of their pets, demand for scientifically backed innovations has grown, and it is a trend that mirrors the rising popularity of similar human-focused longevity research, signaling a shift in how we approach aging across species.
We sat down with Alex Voda, cofounder of The Cat Health Company, to discuss the future of feline longevity and how TCHC plans to turn cutting-edge research into practical treatments for the cats we cherish.
15 Best Longevity Recipes
Posted in food, life extension
Did you know certain seed-heavy fruits like raspberries are actually healthier if you blend them in a smoothie?
I learned this and more while researching for my article on the best longevity recipes:
We took the top anti-aging foods and combined them into a list of the best longevity recipes to help you live a longer, tastier life.
The Quest for Extended Youth
Posted in life extension
The challenges and opportunities of longevity research on the journey to redefine the process and meaning of aging; can the world handle the real impact of prolonging life?
We’re joined by Dr. Denis Noble, Professor Emeritus of Cardiovascular Physiology at the University of Oxford, and the father of ‘systems biology’. He is known for his groundbreaking creation of the first mathematical model of the heart’s electrical activity in the 1960s which radically transformed our understanding of the heart.
Dr. Noble’s contributions have revolutionized our understanding of cardiac function and the broader field of biology. His work continues to challenge long-standing biological concepts, including gene-centric views like Neo-Darwinism.
In this episode, Dr. Noble discusses his critiques of fundamental biological theories that have shaped science for over 80 years, such as the gene self-replication model and the Weissmann barrier. He advocates for a more holistic, systems-based approach to biology, where genes, cells, and their environments interact in complex networks rather than a one-way deterministic process.
We dive deep into Dr. Noble’s argument that biology needs to move beyond reductionist views, emphasizing that life is more than just the sum of its genetic code. He explains how AI struggles to replicate even simple biological systems, and how biology’s complexity suggests that life’s logic lies not in DNA alone but in the entire organism.
Researchers from the Color and Food Quality group at the Faculty of Pharmacy, University of Seville, in partnership with Dr. Marina Ezcurra’s team at the University of Kent (UK), have demonstrated that the carotenoid phytoene extends the lifespan of the nematode Caenorhabditis elegans. Additionally, it delays the onset of paralysis linked to amyloid plaque formation in an Alzheimer’s disease model.
Specifically, increases in longevity of between 10 and 18.6% and decreases in the proteotoxic effect of plaques of between 30 and 40% were observed. The studies, which form part of Ángeles Morón Ortiz’s doctoral thesis, tested pure phytoene and extracts rich in this carotenoid obtained from microalgae.
According to Dr. Paula Mapelli Brahm, “These are very exciting preliminary results, so we are looking for funding to continue this line of research and to find out by what mechanisms these effects are produced.”
LEV Foundation
Posted in biotech/medical, life extension
The LEV Foundation is a nonprofit organization dedicated to advancing the field of rejuvenation biotechnology with the goal of reversing biological aging. Under the leadership of renowned gerontologist Aubrey de Grey, the foundation focuses on conducting early-stage research on animals, specifically testing combination therapies that aim to dramatically extend lifespan. LEV Foundation stands out in the aging research community by targeting middle-aged mice, developing treatments that could one day be applied to humans, helping achieve longevity escape velocity — the point at which aging can be controlled through medical interventions.
U.S. researchers developed CheekAge, a tool that reliably estimates mortality risk.
Researchers in the United States have created a next-generation tool named CheekAge, which uses methylation patterns found in easily obtainable cheek cells.
In a groundbreaking discovery, the team has demonstrated that CheekAge can reliably estimate mortality risk, even when epigenetic data from different tissues are utilized for analysis.
Epigenetic markers are chemical changes to DNA that don’t alter the genetic code but can affect how genes work. Methylation is one such change, often linked to aging. Scientists use these patterns to create “age clocks” that estimate biological age, revealing how fast someone is aging.
Join our in-depth exploration of telomeres and their incredible potential in reversing aging! Discover the science behind telomere enhancement and how it can slow down the aging process. Featuring expert insights from Dr. Michael Roizen, this video unveils cutting-edge research that could change the way we view longevity. #AgingReversal #Telomeres #LongevityScience #DrMichaelRoizen #HealthInnovation #StemCellResearch #AntiAging #YouthfulLiving #Biotechnology #TelomerePharmaceuticals