Lifeboat Foundation: Safeguarding Humanity
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Category: life extension – Page 40

CHANDLER, Ariz. – The radiation-tolerant RTG4 field-programmable gate arrays (FPGAs) with lead-free flip-chip bumps from Microchip Technology Inc. in Chandler, Ariz., have earned the Qualified Manufacturers List (QML) Class V status from the U.S. Defense Logistics Agency (DLA).

These radiation-tolerant FPGAs are for critical space programs. QML Class V is the highest level of qualification for space components for human-rated, deep-space, and national security space programs.

RTG4 FPGAs offer more than 150,000 logic elements, and come in flip-chip package construction where flip-chip bumps connect the silicon die and the package substrate for extended the longevity.

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Choanoflagellates, animals’ closest relatives, have pluripotency genes, reshaping views on their evolution.

The research highlights how evolution repurposes existing genetic tools, turning them into versatile drivers of innovation. This adaptability underscores how foundational processes in unicellular organisms laid the groundwork for the development of complex life forms.

Beyond rewriting evolutionary biology, the findings could revolutionize regenerative medicine. Understanding how ancient genes enabled pluripotency offers new pathways to refine stem cell therapies and enhance cell reprogramming techniques.

For instance, synthetic versions of these genes might outperform native animal genes, opening possibilities for more efficient treatments for diseases or tissue damage.

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Continue reading “Sunlight Deficiency As A Contributor To Poor Health: Roger Seheult, M.D. (‪@Medcram‬)” | >

Genes aren’t the sole driver instructing cells to build multicellular structures, tissues, and organs. In a paper published in Nature Communications, USC Stem Cell scientist Leonardo Morsut and Caltech computational biologist Matt Thomson characterize the influence of another important developmental driver: cell density, or how loosely or tightly cells are packed into a given space.

In both computational models and laboratory experiments, the team of scientists used cell density as an effective tool for controlling how pattern themselves into complex structures.

“This paper represents progress towards our big picture goal of engineering synthetic tissues,” said Morsut, an assistant professor of stem cell biology and regenerative medicine, and biomedical engineering at the Keck School of Medicine of USC.

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We converted the calculations in Morgan Levine and Steve Horvath’s famous research paper on phenotypic age into a free biological age calculator.

It’s a great (cheap) alternative to $400 epigenetic age tests and means you can test more frequently to see if longevity interventions are actually…

This free biological age calculator is based on a pioneering paper by longevity experts Dr. Morgan Levine and Dr. Steve Horvath.

The paper, titled “An epigenetic biomarker of aging for lifespan and healthspan,” used some super-advanced machine learning techniques to find blood biomarkers which are significantly correlated with aging-related health outcomes, including mortality.

Essentially, they are able to use the results from this test to predict how near (or far away) you are from death.

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Basically bio electricity once controlled could offer eternal life for humans because we could simply use the electricity to have longer if not indefinite lifespans that don’t require as much food for energy.

In the near future, birth defects, traumatic injuries, limb loss and perhaps even cancer could be cured through bioelectricity—electrical signals that communicate to our cells how to rebuild themselves. This innovative idea has been tested on flatworms and frogs by biologist Michael Levin, whose research investigates how bioelectricity provides the blueprint for how our bodies are built—and how it could be the future of regenerative medicine.

Levin is a professor of biology at Tufts University and director of the Tufts Center for Regenerative and Developmental Biology.

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Unlock the Secret to a Longer, Healthier Life: The Power of Inhibiting IL-11
Discover the groundbreaking science behind aging in this video, Mr. Bill Faloon presents:
• The Role of IL-11 in Aging: Learn how this inflammatory cytokine accelerates aging and contributes to age-related diseases.
• The Benefits of Inhibiting IL-11: Discover how reducing IL-11 levels can lead to increased lifespan, improved health, and a more youthful appearance.
• Natural Ways to Inhibit IL-11: Learn about dietary supplements and lifestyle habits that can help you lower IL-11 levels.
• The Future of Anti-Aging Medicine: Explore the latest research on drugs and therapies targeting IL-11 and how they may revolutionize the way we approach aging.

https://www.nature.com/articles/s41586-024-07701-9
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386112/
IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10754292/
Understanding interleukin 11 as a disease gene and therapeutic target.

Blocking Inflammation Protein Extends Lifespan


Blocking Inflammation Protein Extends Lifespan.

https://www.telegraph.co.uk/news/2024/07/17/scientists-find-…op-cancer/

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Continue reading “Live Longer, Look Younger: The Groundbreaking Science Of IL-11 Inhibition, 3 Molecules To Reduce It!” | >

Summary: Scientists have reprogrammed mouse cells into pluripotent stem cells using a gene from choanoflagellates, single-celled organisms related to animals. This breakthrough demonstrates that key genes driving stem cell formation existed in unicellular ancestors nearly a billion years ago.

The resulting stem cells were used to create a chimeric mouse, showcasing how ancient genetic tools can integrate with modern mammalian biology. This discovery redefines the evolutionary origins of stem cells and may inform regenerative medicine advancements.

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