Using about 31,000 electronic medical records (EMRs), we developed the mortality biomarker EMRAge and used it to develop OMICmAge by integrating proteomic and metabolomic domains through epigenetic biomarker proxies. This scalable DNA-methylation measure quantifies biological aging, is associated with age-related incident and prevalent diseases, and its performance is comparable to or better than existing biomarkers at predicting mortality.
Is aging actually optional? According to this Harvard scientist, yes—and human trials start soon. He explains why aging is not inevitable but a medical condition we can now treat, sharing groundbreaking results from his lab including reversing blindness in animals and rejuvenating biological age by 75% in just six weeks. The FDA has just approved the first human trials for age reversal, marking a turning point in medical history. This video covers the science, the economics, and a future where we spend our 80s and 90s as healthy as our 40s. This is the update you’ve been waiting for. Credits to World Governments Summit & Dr David Sinclair
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Genetic switches near the FTO locus may enable hibernators’ extreme metabolic resilience and could inspire future treatments for human metabolic and age-related diseases.
Turquoise killifish are naturally short-lived vertebrates that serve as a model system for aging. The authors show that killifish exhibit age-related transformation in the immune system, which rapidly develops inflammation, genome instability and functional decline.
In 2026 we will have first application of Yamanaka Factors in Humans, in human eye. This will open a door to further development in the field of cellular reprograming, aiming full body rejuvenation in not so far future. This is the time to take care of your health and your loved one. Healthier and longer life is already here.
Researchers at The Jackson Laboratory (JAX), in collaboration with the Massachusetts Institute of Technology (MIT), have developed the first bandage-like microneedle patch that can sample the body’s immune responses painlessly from the skin. The device detects inflammatory signals within minutes and collects specialized immune cells within hours without the need for blood draws or surgical biopsies.
Already, the patch is helping researchers and clinicians study immune responses in aging and skin autoimmunity, including vitiligo and psoriasis. In the future, it could make it easier to track how people respond to vaccines, infections, and cancer therapies by complementing traditional blood tests and biopsies while being far easier on patients.
The study appears in Nature Biomedical Engineering.
What if immortality and god-like intelligence were just a few years away? Renowned futurist and former Google engineer Ray Kurzweil predicts that humanity is rapidly approaching a \.