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Changes to actin dynamics during brain aging are not well understood. Here, the authors report that there is an age-related increase in F-actin in Drosophila brain which disables autophagy within the tissue and limits the fly lifespan.

We use our lips to talk, eat, drink, and breathe; they signal our emotions, health, and aesthetic beauty. It takes a complex structure to perform so many roles, so lip problems can be hard to repair effectively. Basic research is essential to improving these treatments, but until now, models using lip cells—which perform differently to other skin cells—have not been available.

In a study published in Frontiers in Cell and Developmental Biology, scientists report the successful immortalization of donated lip cells, allowing for the development of clinically relevant lip models in the lab. This proof-of-concept, once expanded, could benefit thousands of patients.

“The lip is a very prominent feature of our face,” said Dr. Martin Degen of the University of Bern.

When things get tough in adulthood, it might seem appealing to return to simpler times.

One bizarre marine creature has taken this approach to dire situations quite literally, regressing its physical adult body to a juvenile stage once the stress of starvation or injury has subsided.

Until now, the immortal jellyfish (Turritopsis dohrnii) was the only species thought to be able to wind back the clock on jelly-puberty like this, but now it’s joined by Mnemiopsis leidyi, better known as the sea walnut or the warty comb jelly.

We all want to ‘age successfully’ with as few health issues as possible. A new study suggests getting more than seven hours of sleep a night could go a long way to achieving that goal.

The study involved 3,306 participants aged 45 and over, whose sleep habits were recorded in 2011, 2013, and 2015, followed by a health check five years later. The data, analyzed by a team from Wenzhou Medical University in China, showed that those who bank at least seven hours of sleep a night tend to have significantly better health later in life.

“Successful aging was evaluated in 2020 and was defined as being free of major chronic diseases, no physical impairment, high cognitive function, good mental health, and active engagement with life,” write the researchers in their published paper.

A new study from researchers at Wilmer Eye Institute, Johns Hopkins Medicine explains not only why some patients with wet age-related macular degeneration (or “wet” AMD) fail to have vision improvement with treatment, but also how an experimental drug could be used with existing wet AMD treatments…


Wilmer Eye Institute researchers have found that ‘wet’ macular degeneration patients who don’t respond well to treatment have an increased protein in their eyes and that an experimental drug can help improve vision gains. ›