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Archive for the ‘genetics’ category: Page 135

Jun 11, 2022

How Old Cells Rejuvenate To Be YOUNG AGAIN — Cell Autonomous Effect | Dr David Sinclair Clips

Posted by in categories: biotech/medical, economics, genetics, life extension, robotics/AI

Cells not replaced, but old cells that are still there are rejuvenated.


Dr David Sinclair explains the mechanism behind how to reprogramm the old cells rejuvenate to be young again. He also clarify the process is based on cell autonomous effect and does not involve or rely on any stem cells in this clip.

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Jun 10, 2022

Decoding a key part of the cell, atom

Posted by in categories: computing, genetics, nanotechnology, nuclear energy, particle physics

Whatever you are doing, whether it is driving a car, going for a jog, or even at your laziest, eating chips and watching TV on the couch, there is an entire suite of molecular machinery inside each of your cells hard at work. That machinery, far too small to see with the naked eye or even with many microscopes, creates energy for the cell, manufactures its proteins, makes copies of its DNA, and much more.

Among those pieces of machinery, and one of the most complex, is something known as the nuclear pore complex (NPC). The NPC, which is made of more than 1,000 individual proteins, is an incredibly discriminating gatekeeper for the cell’s nucleus, the membrane-bound region inside a cell that holds that cell’s genetic material. Anything going in or out of the nucleus has to pass through the NPC on its way.

Nuclear pores stud the surface of the cell’s nucleus, controlling what flows in and out of it. (Image: Valerie Altounian)

Jun 10, 2022

Whole human genome sequencing for $100

Posted by in categories: biotech/medical, chemistry, computing, genetics, health

“When the Human Genome Project began in 1990, it had a projected budget of $3 billion. […] Now, one company claims to have achieved the major milestone of whole genome sequencing for just $100.”


Ultima Genomics, a biotech company based in California, has emerged from stealth mode with a new high-throughput, low-cost sequencing platform that it claims can deliver a $100 genome.

When the Human Genome Project began in 1990, it had a projected budget of $3 billion. Some researchers believed it would take centuries to map all 20,000+ genes and to determine the sequence of chemical base pairs making up DNA, though in the end it took 13 years. Since then, genome sequencing has undergone technology and cost improvements at a rate faster than Moore’s Law (a long-term trend in the computer industry that involves a doubling of performance every two years). What used to require billions of dollars and many years of work is now several orders of magnitude cheaper and possible in a matter of hours.

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Jun 9, 2022

Beefalo, a bison-cattle hybrid, is being touted as the healthy meat of the future

Posted by in categories: food, genetics

Not that Thier should be more animals raised for meat.


But beefalo does have its opponents.

“We just don’t think there should be beefalo,” said Martha McFarland, farmland viability coordinator for the advocacy group Practical Farmers of Iowa. She also raises cattle and bison, but said she would never mix the two.

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Jun 9, 2022

Concurrent Heart Conditions Linked to Tripled Dementia Risk

Posted by in categories: biotech/medical, genetics, life extension, neuroscience

Having multiple conditions that affect the heart are linked to a greater risk of dementia than having high genetic risk, according to a largescale new study.

Led by Oxford University and the University of Exeter, the study is among the largest ever to examine the link between several heart-related conditions and dementia, and one of the few to look at the complex issue of multiple health conditions.

Published in The Lancet Healthy Longevity, the paper looked at data from more than 200,000 people, aged 60 or above, and of European ancestry in UK Biobank. The international research team identified those who had been diagnosed with the cardiometabolic conditions diabetes, stroke, or a heart attack, or any combination of the three, and those who went on to develop dementia.

Jun 8, 2022

Cellular secrets unlocked by researchers lead to new theory for aging

Posted by in categories: biotech/medical, genetics, life extension

New research has uncovered how genetic changes that accumulate slowly in blood stem cells throughout life are likely to be responsible for the dramatic change in blood production after the age of 70.

The study, by scientists at the Wellcome Sanger Institute, the Wellcome-MRC Cambridge Stem Cell Institute and collaborators, has been published in the journal Nature.

Longevity. Technology: Has our understanding of one of the mechanisms of aging taken a quantum leap? Molecular damage accumulates throughout our lives, gradually increasing year-on-year as we suffer telomere attrition, mutation, epigenetic change and oxidative and replicative stress. It’s a double whammy as our ability to repair this damage also declines as we age, but given the gradual nature of these processes, why, as the paper authors themselves put it, “Is there an abrupt increase in mortality after 70 years of age? [1].

Jun 7, 2022

NOT The Longevity Genes!? Surprising Facts WHY Centenarians LIVE LONGER | Dr Nir Barzilai Clips

Posted by in categories: biotech/medical, genetics, life extension

“Functional mutations in the growth hormone pathway” meaning it is not active. What’s good for you as a youngster might not be good for you when you’re old.


Dr Nir Barzilai reveals what the longevity genes project found on why Centenarians live longer, not the longevity genes, not healthy lifestyles in this clip.

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Jun 7, 2022

Drug combination shows promise against cancer’s ‘death star’ protein

Posted by in categories: biotech/medical, genetics

A drug combination targeting multiple mutant versions of cancer’s “death star” protein has shown promise in a small, early-phase clinical trial for some patients with advanced lung, ovarian and thyroid cancer.

The two– was effective against with a range of mutations to the KRAS gene—dubbed the “death star” because its protein drives one in four cancers and has a largely impenetrable, drug-resistant surface.

The phase I trial tested the drugs VS-6766 and everolimus in 30 patients with a range of mutations to KRAS—including 11 with highly advanced, .

Jun 6, 2022

A New Kind of Genome Editing Is Here to Fine-Tune DNA

Posted by in categories: biotech/medical, genetics

Instead of deleting genes, epigenetic editing modulates their activity. A new paper tests if it’s able to undo a genetic effect of early alcohol exposure.

Jun 6, 2022

WHO Is The OBSERVER That Holds The Key For OUR YOUTHFULNESS? | Dr David Sinclair Interview Clips

Posted by in categories: biotech/medical, economics, genetics, quantum physics

Observer, backup youthful copy, playing the right piano notes, quantum states oh my.


Dr David Sinclair explain about through his lab experiments, why he thinks there is an observer/backup copy for our youthfulness and what are the possible identities he can think of in this clip.

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