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Engineers develop technology that stimulates heart cells with light

In a new study, University of California, Irvine chemical and biomolecular engineering researchers report the creation of biomolecules that can help grow light-sensitive heart muscle cells in the laboratory. The development enables a biotechnology that could deliver light-triggered signals to the heart, improving its function, without requiring genetic modifications or invasive procedures.

“We show for the first time that light can be converted into cardiac stimulatory cues, with made of biomolecules,” said Herdeline Ann Ardoña, assistant professor of chemical and biomolecular engineering. “This can be beneficial for downstream medical applications, such as in cardiac pacemaking technologies, or helping direct therapeutic patient-derived stem to better mimic adult heart cell features.”

The findings are reported in the Proceedings of the National Academy of Sciences. The paper’s co-first authors are recent Ph.D. graduate Sujeung Lim, and Ze-Fan Yao, previous postdoctoral scholar in the Ardoña Research Group.

Caltech Researchers Upend Decades-Old Model of Mitochondrial Protein Import

Researchers showed that many mitochondrial proteins enter the organelle during synthesis, guided by folding patterns and structural signals. This discovery revises decades of biochemical models. Mitochondria are organelles most commonly known as the “powerhouses of the cell” because they generate

NASA finds Titan’s alien lakes may be creating primitive cells

Saturn’s moon Titan may be more alive with possibilities than we thought. New NASA research suggests that in Titan’s freezing methane and ethane lakes, simple molecules could naturally arrange themselves into vesicles—tiny bubble-like structures that mimic the first steps toward life. These compartments, born from splashing droplets and complex chemistry in Titan’s atmosphere, could act like primitive cell walls.

NASA research has shown that cell-like compartments called vesicles could form naturally in the lakes of Saturn’s moon Titan.

Titan is the only world apart from Earth that is known to have liquid on its surface. However, Titan’s lakes and seas are not filled with water. Instead, they contain liquid hydrocarbons like ethane and methane.

US Energy Secretary’s INSANE Bet Against Elon Musk

Questions to inspire discussion.

Energy for AI and Infrastructure.

🤖 Q: How does AI development impact energy demands? A: AI development will drive massive demand for electricity, with solar and batteries being the only energy source with an unbounded upper limit to scale and meet these demands.

⛽ Q: Can solar energy support existing infrastructure? A: Solar energy can produce synthetic biofuels and oil and gas through chemical processes, enabling it to power existing infrastructure that runs on traditional fuels.

Expert Predictions.

🚗 Q: What does Elon Musk predict about future energy sources? A: Elon Musk predicts that solar and batteries will dominate the future energy landscape, citing China’s massive investment as a key factor in this prediction.

Laser reveals sound from supersonic molecules in near-space cold conditions

What happens when you hurl molecules faster than sound through a vacuum chamber nearly as cold as space itself? At the University of Missouri, researchers are finding out—and discovering new ways to detect molecules under extreme conditions.

The discovery could one day help chemists unravel the mysteries of astrochemistry, offering new clues about what the universe is made of, how stars and planets form and even where life originated.

In a recent study published in The Journal of Physical Chemistry A, Mizzou faculty member Arthur Suits and doctoral student Yanan Liu fired a laser at methane gas molecules moving faster than the in a at roughly −430°F, close to the temperature in parts of outer space.

Habitable planet potential increases in the outer galaxy

What can the galactic habitable zone (GHZ), galactic regions where complex life is hypothesized to be able to evolve, teach scientists about finding the correct stars that could have habitable planets?

This is what a recent study accepted for publication in Astronomy & Astrophysics hopes to address as an international team of researchers investigated a connection between the migration of stars, commonly called stellar migration, and what this could mean for finding habitable planets within our galaxy. This study has the potential to help scientists better understand the astrophysical parameters for finding habitable worlds beyond Earth and even life as we know it. The findings are published on the arXiv preprint server.

For the study, the researchers used a series of computer models to simulate how stellar migration could influence the location and parameters of the GHZ. The models included scenarios both with and without stellar migration to ascertain the statistical probabilities for terrestrial (rocky) planets forming around stars throughout the galaxy. The researchers also used a chemical evolution model to ascertain the formation and evolution of our galaxy, specifically regarding its thickness.

The Case for Life on Mars Just Got Stronger

“This finding by Perseverance …is the closest we have ever come to discovering life on Mars,” said acting NASA administrator Sean Duffy in a statement. “The identification of a potential biosignature on the Red Planet is a groundbreaking discovery, and one that will advance our understanding of Mars.”

Perseverance did not discover fossilized microbes and it surely didn’t discover living ones. What it found was a rock streaked in a range of colors—red, green, purple, and blue—flecked with poppy-seed-like dots and decorated with what the Perseverance scientists compared to dull yellow leopard spots. That said a lot. As the rover’s instruments confirmed, the red is iron-rich mud, the purple is iron and phosphorous, the yellow and green are iron and sulfur. All of those elements serve as something of a chow line for hungry microbes.

The poppy seeds and leopard spots, meantime, resemble markings left behind by metabolizing microbes on Earth. When the rover trained its instruments on those features they detected two iron-rich minerals—vivianite and greigite. On Earth, vivianite is frequently found in peat bogs and around decaying organic matter—another item on the microbes’ menu. And both minerals can be produced by microbial life. Images of the rock with its distinctive features were beamed back to Earth by Perseverance, while X-ray and laser sensors analyzed the chemistry of the markings.

Pinning down protons in water—a basic science success story

The movement of protons through electrically charged water is one of the most fundamental processes in chemistry. It is evident in everything from eyesight to energy storage to rocket fuel—and scientists have known about it for more than 200 years.

But no one has ever seen it happen. Or precisely measured it on a microscopic scale.

Now, the Mark Johnson lab at Yale has—for the first time—set benchmarks for how long it takes protons to move through six charged . The discovery, made possible with a highly customized mass spectrometer that has taken years to refine, could have far-reaching applications for researchers in years to come.

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