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Visible light triggers three-step cascade to make 3D drug-like molecules

A team led by chemist Frank Glorius, a professor at the Institute of Organic Chemistry at the University of Münster, has developed a new light-driven reaction sequence. In this triple catalysis, one reaction step triggers the next like three dominoes in a row, toppling one after the other. The molecular transformations occur sequentially in a single reaction vessel. Such one-pot synthesis is considered an ideal process because it is particularly resource- and energy-efficient.

Harvard scientists turn a silicon chip into a DNA writing machine

Scientists have created a silicon chip that can write dozens of DNA sequences simultaneously using electricity and water-based enzymes, offering a cleaner alternative to conventional DNA manufacturing. The breakthrough could eventually support portable DNA-writing devices and even massive DNA data storage, although new chemistry will be needed to scale the technology further.

Astronomers Have Now Spotted Galaxies So Far Away, It Raises Troubling Questions

Recent observations from the James Webb Space Telescope have revealed a massive galaxy cluster and an extraordinarily ancient galaxy that directly challenge the standard model of cosmology. The standard model suggests gravity acts as a patient engine that takes billions of years to slowly assemble raw gas into cosmic structures. But JWST data shows a gargantuan, tightly packed galaxy cluster existing just a few billion years after the Big Bang, warping space with a highly organized dark matter core that should not exist so early.

Looking even further back to a mere 280 million years post-Big Bang, astronomers found MoM-z14, a galaxy that is far brighter and more chemically evolved than early formation models predict. Finding such heavy and mature structures so early indicates that the fundamental timeline for how the universe assembled its mass is missing a critical piece of the puzzle.

0:00 Discovery of Galaxy Cluster XLSSC 122
2:50 Mother of Miracles.
3:26 The Cosmic Dawn.
4:26 The Farthest Galaxy Candidate.
8:32 Distribution of Galaxy Rotation.
9:38 Black Hole Cosmology.

Source:
https://iopscience.iop.org/article/10… https://academic.oup.com/mnras/articl… Music: Artlist Ltd Voice Over: Mathew McQuinn Buy us a cup of coffee: / @territoryspace When you buy from our store, you support us: https://my-store-10522d3.creator-spri… Visit our website: https://www.territoryspace.com/ Subscribe to Territory — / @territoryspace Instagram — instagram.com/territoryspace.
https://arxiv.org/pdf/2505.11263v2
https://academic.oup.com/mnras/articl…

Music: Artlist Ltd.

Voice Over: Mathew McQuinn.

Discovery helps explain why solid-state batteries often fail

Exactly how those dendrites form is still up for debate. While the interface between the battery’s electrolyte and electrodes has been the focus of most research, another culprit is the boundary where two grains of electrolyte in a solid material meet. Researchers know these boundaries can seed dendrites within electrolytes, although the effects have been difficult to study.

Now researchers at MIT and the Technical University of Munich have uncovered why such boundaries can lead to dendrites: Hidden electrical imbalances across the boundaries affect how the electrolyte conducts electrical charges, which influences how the ions and electrons move through the material during battery operation. In a paper published today in Nature Nanotechnology, the researchers characterized the electrical and chemical behavior of the boundaries and showed that adjusting how the electrolyte is processed enhances the movement of ions while reducing electron leakage. This adjustment can increase critical current density by more than 300 percent, which could enable solid-state batteries that charge faster and last longer.

Light-powered chip harvests energy, computes and senses chemicals in one stack

Most contemporary portable electronics, including laptops, smartphones and smart watches, are powered by batteries that need to be recharged daily or every few days. Over the past decade, however, some engineers have been exploring the possibility of developing battery-free electronic devices that autonomously derive electricity from renewable sources, such as sunlight, indoor lighting or heat.

A research team at Penn State University recently developed a compact integrated circuit (IC) that harvests energy solely from ambient light, using this energy to run computations and sense chemicals in its surroundings. This new chip, introduced in a paper published in Nature Electronics, could enable the development of devices that never require charging and thus continue working uninterrupted even in environments where replacement batteries and electrical sockets are not available.

“This work grew out of a broader question we have been asking in my group: Can we build electronic systems that do not simply sense information, but also process that information locally and power themselves from their environment?” Saptarshi Das, senior author of the paper, told Tech Xplore. “Many future Internet of Things (IoT) and edge-computing systems will need to operate in remote or hard-to-access locations, where replacing batteries is impractical. We wanted to demonstrate a compact, fully integrated chip that combines energy harvesting, sensing and computation in a single monolithic three-dimensional architecture.”

Baseline tool could separate alien life signals from geology on ocean worlds

When it comes to the search for life elsewhere in the universe, methane and other chemical compounds are seen as signs of biology because they are often produced by living microbes. However, scientists can be misled because certain geological processes can produce chemical signatures identical to those of living organisms.

To help identify true biological signals and reduce the risk of false detections, researchers have developed a framework that models what a planet’s chemistry looks like without life.

Their research is published in the journal Nature Astronomy.

Saturn-ring-like laser emission from chiral polymeric microspheres

Controlling light within microscopic spaces is crucial for next-generation optical devices such as photonic integrated circuits and localized sensors. Microspheres formed of luminescent π-conjugated polymers act as optical resonators that confine and amplify light via whispering gallery modes (WGMs), and they are promising candidates for microscale organic lasers and photonic applications. However, conventional microsphere resonators are geometrically isotropic and emit isotropic light, making directional control of emissions challenging.

In a new study published in the Journal of the American Chemical Society, researchers from the University of Tsukuba show that microspheres formed through the self-assembly of chiral π-conjugated polymers possess a characteristic twisted bipolar molecular configuration, enabling angle-selective optical resonance and laser oscillation with distinct azimuthal directionality. Using polarization-dependent photoluminescence imaging, the research team directly visualized a vortex-like (swirling) arrangement formed by the polymer main chains on the spherical surface.

Furthermore, this vortex-like surface molecular orientation induces an azimuth-dependent refractive-index distribution along the light propagation path, resulting in angle-dependent WGM resonance wavelengths and spatially localized emission. Consequently, the microspheres exhibit directional laser oscillation, preferentially emitting amplified light along a specific azimuthal direction. The resulting emission pattern is analogous to Saturn’s rings.

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