Your chances of catching a cold—and how miserable it feels—may depend more on your body than on the virus itself.
Scientists have long known that inherited neurodegenerative disorders, including Alzheimer’s, Parkinson’s or motor neuron disease, can be traced back to genetic mutations. However, how they cause the diseases remains unanswered.
In today’s issue of the journal Current Biology Professor Andreas Prokop revealed that so-called “motor proteins” can provide key answers in this quest.
The research by the Prokop group focuses on nerve fibers, also called axons. Axons are the delicate biological cables that send messages between the brain and body to control our movements and behavior. Intriguingly, axons need to survive and stay functional for our entire lifetime.
Researchers have developed a novel noninvasive coronary artery bypass approach that may offer an alternative to traditional open-heart surgery for select patients with coronary disease. Early experience suggests this technique could reduce surgical trauma and change how some coronary conditions are treated, although broader clinical validation will be needed to define its role in future practice.
Researchers have created a new noninvasive technique for performing a type of artery bypass that may change the future of some coronary surgeries.
As many of us embark on an exercise or gym routine for the new year, research reveals that just 10 minutes of intense exercise could help fight cancer.
Short bursts of energetic activity can trigger rapid molecular changes in the bloodstream, shutting down bowel cancer growth and speeding up DNA damage repair, a new study has shown.
Researchers at Newcastle University have found that exercise increases the concentration of several small molecules in the blood—many linked to reducing inflammation, improving blood vessel function, and metabolism.
Can Alzheimer’s be reversed? Dr. Insoo Hyun explains how scientists at Case Western Reserve University are exploring that possibility by restoring NAD+, a vi…
The androids of the future will be the distant results of synthetic biology and not silicon.
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In a surprising discovery, University of New Mexico researchers have found that OTULIN – an enzyme that helps regulate the immune system – also drives the formation of tau, a protein implicated in many neurodegenerative diseases, as well as brain inflammation and aging.
In a study published in the journal Genomic Psychiatry, the researchers reported that when they deactivated OTULIN, either by administering a custom-designed small molecule or knocking out the gene that codes for it, it halted the production of tau and removed it from neurons. The study was conducted on two different types of cells, some derived from a patient who had died from late-onset sporadic Alzheimer’s disease, and the rest from a line of human neuroblastoma cells that are frequently used in neuroscience research.
The discovery opens the door to potential treatments for Alzheimer’s and other neurodegenerative diseases, said Karthikeyan Tangavelou, PhD, a senior scientist in the lab of Kiran Bhaskar, PhD, professor in the Department of Molecular Genetics & Microbiology in the UNM School of Medicine.