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Researchers have developed nanoflower-coated bandages with antibiotic and anti-inflammatory properties, capable of killing bacteria and promoting wound healing.

A carnation-like nanostructure could one day be used in bandages to promote wound healing. Researchers report in ACS Applied Bio Materials that laboratory tests of their nanoflower-coated dressings demonstrate antibiotic, anti-inflammatory, and biocompatible properties.

They state that these results indicate tannic acid and copper(II) phosphate sprouted nanoflower bandages are promising candidates for treating infections and inflammatory conditions.

When synthesizing chemicals, stationary sensors can collect and communicate detailed data from within a reactor system. Physically installed sensors reach their limitations when it comes to mapping concentrations within a fluid flowing through hard-to-reach areas—particularly within long, narrow tubes.

While can be placed on the reactor’s perimeter in an industrial setting, suspending sensors in the center of a pipe would disrupt flow. In a medical application, such as mapping within the intestines to pinpoint , implanted sensors become impractical.

A new framework optimizes the use of time-aware particulate sensors (TAPS)—a that travels through the system and remembers when it encounters a target chemical—to map these uncharted areas.

New genetic research from the University of Florida may help make key crops such as potatoes, tomatoes, and peppers more resistant to disease and environmentally resilient as well as increase their nutritional value.

“Our research illustrates the remarkable potential of combining deep taxonomic expertise with cutting-edge biotechnology,” author Fabio Pasin told the Chinese Academy of Sciences, via Phys.org. “By focusing on the Solanaceae family, we can enhance not only widely recognized crops but also bring underutilized species into the agricultural mainstream, improving food security and enriching nutritional diversity across the globe.”

Researchers used recombinant virus technologies to give new breeds of plants particular traits. This method is very specific about promoting certain traits in new breeds. Scary as it might sound to use an engineered virus to change the DNA of our food, it’s a way of improving biodiversity in agriculture when farming has become more and more homogeneous and thus vulnerable.

Hi Spacecats, I’m Dr Maggie Lieu and welcome to my channel, where you can find all things space, astronomy and physics! Ever wondered what’s beyond the observable universe? This video explains the concept of the observable universe, the expansion of space, and explores theories about what might lie beyond, from infinite space to the multiverse.

Media credits:
expansion universe: ESO/Calçada.
galaxies: ESA/Hubble/DSS/Risinger.
Expansion Universe: Kornmesser/Calcada/NASA/ESA/Hubble.

Special thanks to my YouTube Members: Annex Celestial, Wheely Big Bike Trip, Steven Yee, Anders Welander, Bill Fratt, David Brant, John Lewis, Christopher Senn, Gregory McCoy, Nigel Draper, Jordan Workshop, Tom Organ, Rico, Arcane Domain, macgonzo & Vlad Cristian Eremia.

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/ @spacemog.

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Dementia with Lewy Bodies (DLB), Parkinson’s disease (PD) and PD dementia (PDD) are neurodegenerative syndromes that are characterized neuropathologically by Lewy body disease (LBD), including Lewy bodies in neuronal somata and Lewy neurites in axons or dendrites. Intraneuronal aggregates of tau called neurofibrillary tangles (NFTs) classically are associated with Alzheimer’s disease (AD), yet NFTs often are observed with LBD as well [40]. PDD patients have a higher burden of NFTs in the cortex compared to PD patients without dementia, and cortical tau aggregates correlate with cognitive impairment severity [15, 21, 22]. Mouse models of LBD implicate an α-syn-tau interaction. In mice overexpressing A53T mutant human α-syn, knocking out tau or using antibodies targeting oligomeric tau reverses memory impairments [19, 39]. Thus, the presence of both Lewy and tau pathology may contribute to cognitive symptoms from LBD.

Endogenous tau and α-synuclein colocalize and associate in neurons [42], suggesting that co-pathology may arise from synergistic interactions. Indeed, in vitro experiments show that tau’s microtubule binding domain also binds the C-terminus of α-syn, resulting in the fibrillization and aggregation of both proteins [17, 20]. In addition, human postmortem studies report colocalization between tau and synuclein using various antibody combinations. LBD colocalizes with tau in brainstem Sect. [2], hippocampus [3], entorhinal cortex [23], frontal cortex [38], amygdala [37, 43], and olfactory bulb [18]. One study quantified the number of double-positive neurons across hippocampal structures and determined the subiculum and pre-CA1 neurons had the highest proportion for double-positivity with a range of 1–13% across 5 subjects, as assessed by examining neuronal somata [24]. In another study that focused on brainstem Lewy bodies, as many as a third of Lewy bodies in the medulla were immunoreactive for phosphorylated tau, but a relationship between tau and α-syn immunoreactivity within abundant Lewy neurites has not been examined [25]. In addition, many of the studies showing overlap of α-syn and tau pathology are qualitative or relied on counting colocalization by eye in single images rather than quantifying colocalization over a larger area within the tissue.

Investigating overlap of pathologic α-syn and tau in structures including neurites is important because synaptic and axonal dysfunction are earlier pathophysiologic events in LBD than the formation of Lewy bodies, and cortical and limbic regions affected by α-synucleinopathy show more abundant Lewy neurites than Lewy bodies. We examined postmortem middle temporal gyrus cortex from human brains with confirmed LBD using immunofluorescence and confocal microscopy. We first quantified the degree of abnormal forms of α-syn and tau as well as immunologic markers for this region, showing an association of disease markers with the neuropathological diagnosis of LBD, demonstrating these cases recapitulate prior findings from the literature. We then measured colocalization of pathologic α-syn with phosphorylated tau, and an early pathologic form of tau.

Within a large group of more than 700 patients treated with CAR T cell therapy, researchers found no evidence that the therapy itself caused any type of secondary cancer in the modified T cells, according to new analysis reported today in Nature Medicine from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine’s Abramson Cancer Center.

A major international study reveals that most people with cardiovascular disease.

Cardiovascular disease (CVD) encompasses a range of disorders affecting the heart and blood vessels, including coronary artery disease, heart attack, stroke, and hypertension. These conditions are primarily driven by atherosclerosis, a process where plaque builds up in the arterial walls, leading to narrowed or blocked arteries. Risk factors include smoking, unhealthy diet, lack of exercise, obesity, and genetic predisposition. CVD remains a leading cause of global mortality, emphasizing the importance of lifestyle changes, medical interventions, and preventive measures in managing and reducing the risk of heart-related illnesses.

The future of medicine may very well lie in the personalization of health care—knowing exactly what an individual needs and then delivering just the right mix of nutrients, metabolites, and medications, if necessary, to stabilize and improve their condition. To make this possible, physicians first need a way to continuously measure and monitor certain biomarkers of health.

To that end, a team of Caltech engineers has developed a technique for inkjet printing arrays of special that enables the mass production of long-lasting wearable sweat sensors. These sensors could be used to monitor a variety of biomarkers, such as vitamins, hormones, metabolites, and medications, in real time, providing patients and their physicians with the ability to continually follow changes in the levels of those .

Wearable biosensors that incorporate the new nanoparticles have been successfully used to monitor metabolites in patients suffering from long COVID and the levels of chemotherapy drugs in at City of Hope in Duarte, California.

Researchers at the University of Kentucky are exploring new ways to use nanoparticles in combination with other materials as an innovative approach to cancer therapy.

The paper titled “Iron Oxide Nanozymes Enhanced by Ascorbic Acid for Macrophage-Based Cancer Therapy” was published earlier this year in Nanoscale.

Sheng Tong, Ph.D., an associate professor in the F. Joseph Halcomb II, M.D., Department of Biomedical Engineering in the UK Stanley and Karen Pigman College of Engineering, led the study.

If you have ever had your blood drawn, whether to check your cholesterol, kidney function, hormone levels, blood sugar, or as part of a general checkup, you might have wondered why there is not an easier, less painful way.

Now there might be. A team of researchers from Caltech’s Cherng Department of Medical Engineering has unveiled a new wearable sensor that can detect in even minute levels of many common nutrients and biological compounds that can serve as indicators of human health.

The was developed in the lab of Wei Gao, assistant professor of , Heritage Medical Research Institute investigator, and Ronald and JoAnne Willens Scholar. For years, Gao’s research has focused on with medical applications, and this latest work represents the most precise and sensitive iteration yet.