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Study critiques the World Health Organizationâs fungal priority pathogens list for not fully reflecting the global burden of fungal diseases, advocating for a revised list that considers regional disparities and elevates the priority of pathogens like Mucorales and Histoplasma spp. to better align with their impact on public health.
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Comprehensive review reveals the significant impact of tumor-resident bacteria on metastatic cancer, showing how microbiome genomes influence tumor biology, immune system response, and treatment effectiveness. It lays the groundwork for utilizing bacteria-focused therapies to complement traditional cancer treatments.
Dive into this newest article featuring an unique case study of Pituitary Apoplexy in Macroadenoma following minor surgery. Explore more by tapping the link đ
Pituitary apoplexy is a rare and severe complication of pituitary adenoma that may present with new-onset headache, ocular palsy, visual disturbances, life-threatening electrolyte imbalance, and endocrinological disturbances due to pituitary hemorrhage and/or infarction.
We report the case of a 58-year-old previously healthy patient who developed isolated mild oculomotor nerve palsy of the left eye following osteosynthesis of a traumatic right distal radius fracture. Initial cerebral magnetic resonance imaging showed a pituitary macroadenoma without characteristic signs of pituitary infarction or hemorrhage. The patient presented to the neurology department on the fifth postoperative day with malaise and fatigue due to pituitary insufficiency, deteriorated rapidly and required intensive care monitoring.
Is Chief Impact Officer for StartUp Healthâs Alzheimerâs Moonshot (https://www.startuphealth.com/alzheimers), a new global initiative created to develop a collaborative innovation community alongside leading companies, research teams, and stakeholders, with a mission to accelerate progress in prevention, diagnosis, and management of Alzheimerâs disease and related dementias. With support from the Alzheimerâs Drug Discovery Foundation (ADDF) and Gates Ventures, StartUp Health is looking to break down silos and foster meaningful collaboration between mission-aligned founders, funders, and partners.
Dr. Ferrell also serves as Strategic Advisor, Davos Alzheimerâs Collaborative (https://www.davosalzheimerscollaboratâŠ) which is building a global clinical trial network and technology platform that will link trial sites around the world.
Prior to these roles, Dr. Ferrell served almost three decades at multiple roles at Eli Lilly including as Global Head External Engagement, Alzheimerâs and Neurodegeneration, Chief Commercial Services Officer, and Vice President, Global Alzheimerâs Disease Platform Team Leader in Lilly BioMedicines, where her team were responsible for the late-stage development, global registration and launch of 4 late-stage assets including Solanezumab, Amyvid and AZD3293.
Dr. Ferrell received a DrPH, Public Health from Indiana University Richard M. Fairbanks School of Public Health, an MBA in General Management and a certificate in Public Management from the Stanford University Graduate School of Business, and a Bachelor of Arts degree in economics and management from DePauw University.
Dr. Ferrell was recognized with the Rising Star Award from the Healthcare Businesswomenâs Association and the Indianapolis Star Top 40 Under 40. She serves as a member of the World Dementia Council, a steering committee member of the Milken Institute Center for Aging Alliance for Dementia Care and National Minority Quality Forum (NMQF) Alzheimerâs Disease Index working groups, and a strategic reviewer for the Alzheimerâs Disease Drug Discovery Foundation Diagnostics Accelerator. She is also a member of the Indiana Chapter of the Healthcare Businesswomenâs Association; on the Boards of Directors for Alzheimerâs Research UK EDoN, Gates Ventures Alzheimerâs Disease Data Initiative, the Indiana Chapter of the Alzheimerâs Association, Stanford Associate Board of Governors, Indianapolis 500 Festival, and the Lebanon Area Boys \& Girls Club. She is a founding member of Women Against Alzheimerâs and Women of Impact Boone County; co-chair of the Womenâs Leadership Council; the alumna sponsor of the Women in Economics and Business Program at DePauw University; a member of the Washington C. DePauw Society; a Tocqueville donor to United Way; an active supporter of Boone County Special Olympics and the Boone County Community Foundation.
Doctors in New York have performed the worldâs first successful face and double hand transplant. Joe DiMeo, 22, underwent the 23-hour surgery, performed by aâŠ
The extracellular matrix is an essential component of the tumor microenvironment and affects cancer progression. Weeraratna and colleagues have now uncovered that age-related reductions in the level of hyaluronan and proteoglycan link protein 1 (HAPLN1) stimulate neoangiogenesis and compromise the vascular integrity of intratumoral blood vessels. These biological modifications converge to fuel distant melanoma metastasis.
The child required a specific nutrient blend to optimize health and reduce kidney strain.
Prescription drugs helped a toddler born with a rare and chronic kidney disease receive a kidney transplant and escape the net of repeated dialysis sessions, all due to the efforts of his mother and the team of doctors.
The toddler, Dinero Motton, had been diagnosed with a lower urinary tract obstruction and enlarged bladder when he was still in his motherâs womb.
In a global research effort, scientists have uncovered a relationship between metabolism problems in the brain and a range of neuropsychiatric and neurodegenerative disorders, from autism to Alzheimerâs disease and more.
Despite their diverse symptoms, these conditions â as well as depression, epilepsy, schizophrenia, intellectual disability, and bipolar disorder â all involve a degree of cognitive impairment and often share genetic or metabolic features, hinting at a common biological basis.
The extensive collaboration by the International Brain pH Project Consortium, involving 131 scientists from 105 labs in seven countries, identified changes in brain acidity and lactate levels in animals as key signs of this metabolic dysfunction.
