Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: biotech/medical – Page 364

New lightweight polymer film can prevent corrosion

MIT researchers have developed a lightweight polymer film that is nearly impenetrable to gas molecules, raising the possibility that it could be used as a protective coating to prevent solar cells and other infrastructure from corrosion, and to slow the aging of packaged food and medicines.

The polymer, which can be applied as a film mere nanometers thick, completely repels nitrogen and other gases, as far as can be detected by laboratory equipment, the researchers found. That degree of impermeability has never been seen before in any polymer, and rivals the impermeability of molecularly-thin crystalline materials such as graphene.

“Our polymer is quite unusual. It’s obviously produced from a solution-phase polymerization reaction, but the product behaves like graphene, which is gas-impermeable because it’s a perfect crystal. However, when you examine this material, one would never confuse it with a perfect crystal,” says Michael Strano, the Carbon P. Dubbs Professor of Chemical Engineering at MIT.

Accelerating therapies for brain conditions

This pace of discovery might be expected given the extreme intricacy of the brain and psychiatric disorders.

“The brain is incredibly complex — we’re talking about tens of billions of neurons with trillions of connections,” says Kozo Kaibuchi, director of the International Center for Brain Science (ICBS) at Fujita Health University, near Nagoya in Japan. “Psychiatric and neurological disorders are also highly diverse — often involving subtle changes on a spectrum rather than one obvious cause.”

On top of that, there are further obstacles that hinder progress in developing treatments for these conditions — the difficulty of imaging inside the human brain; the scarcity of human-like models; and the blood–brain barrier, which prevents most drugs from entering the brain.

First Ever Programmable DNA Circuit Is a Breakthrough In Biocomputing

Get a Wonderful Person Tee: https://teespring.com/stores/whatdamath.
More cool designs are on Amazon: https://amzn.to/3wDGy2i.
Alternatively, PayPal donations can be sent here: http://paypal.me/whatdamath.

Hello and welcome! My name is Anton and in this video, we will talk about an invention of a DNA bio computer.
Links:
https://www.nature.com/articles/s41586-023-06484-9
https://www.washington.edu/news/2016/04/07/uw-team-stores-di…perfectly/
Other videos:
https://youtu.be/x3jiY8rZAZs.
https://youtu.be/JGWbVENukKc.

#dna #biocomputer #genetics.

0:00 Quantum computer hype.
0:50 Biocomputers?
1:55 Original DNA computers from decades ago.
3:10 Problems with this idea.
3:50 New advances.
5:35 First breakthrough — DNA circuit.
7:30 Huge potential…maybe.

Support this channel on Patreon to help me make this a full time job:
https://www.patreon.com/whatdamath.

Bitcoin/Ethereum to spare? Donate them here to help this channel grow!
bc1qnkl3nk0zt7w0xzrgur9pnkcduj7a3xxllcn7d4
or ETH: 0x60f088B10b03115405d313f964BeA93eF0Bd3DbF

Space Engine is available for free here: http://spaceengine.org.

Continue reading “First Ever Programmable DNA Circuit Is a Breakthrough In Biocomputing” | >

New study finds bacteria in brain tumors play ‘surprising’ role in cancer growth

Newly published research in the peer-reviewed journal Nature Cancer suggests that bacteria inside brain tumors may play a far more active role in how cancers grow, spread and respond to treatment than previously understood, according to Prof. Ravid Straussman of the Weizmann Institute of Science.

For years, scientists considered tumors as places where bacteria didn’t grow.

If this problem persists, please email us at support AT timesofisrael.com.

Be sure to include in your email the following details:

Your IP 2600:3c00::f03c:92ff: fe29:18d2.

An Immunomodulating Peptide with Potential to Promote Anticancer Immunity Without Compromising Immune Tolerance

Background: Immune checkpoint inhibitor therapy in patients with lung cancer and metastatic melanoma is associated with exacerbation of autoimmune-related diseases. The efficacy of treatment targeting the programmed cell death receptor-1 (PD-1) checkpoint relies upon a feedback loop between interferon gamma (IFN-γ) and the interleukin-12 isoform, IL-12p40. Paradoxically, both cytokines and the anti-PD-1 antibody worsen psoriasis. We previously reported an immunomodulating peptide, designated IK14004, that inhibits progression of Lewis lung cancer in mice yet uncouples IFN-γ from IL-12p40 production in human immune cells. Methods: Immune cells obtained from healthy donors were exposed to IK14004 in vitro to further characterise the signalling pathways affected by this peptide.

How brain fluid flow predicts survival in glioblastoma

Glioblastoma—the most aggressive form of brain cancer—remains one of medicine’s biggest challenges. Despite surgery, radiotherapy, and chemotherapy, most patients survive only about a year after diagnosis.

However, a new discovery might change how doctors understand and monitor this . Specifically, the study focused on isocitrate dehydrogenase (IDH) wild-type glioblastoma, the most common and rapidly growing form of the tumor, known for its and limited treatment options.

In a study published in Neuro-Oncology, researchers found that brain regions far away from the tumor—known as the contralateral hemisphere (the side opposite to tumor)—can reveal vital clues about a patient’s survival in IDH wild-type glioblastoma.

Reversing fibrosis: New research provides insight for novel therapies

Yale School of Medicine (YSM) researchers have made key breakthroughs in understanding how to treat fibrotic diseases such as scleroderma and graft-versus-host disease.

Fibrotic diseases are a group of conditions—often autoimmune—characterized by excessive tissue scarring. They can drastically hinder patients’ quality of life, and in some cases, they can be life-threatening— contributes to approximately 45% of all deaths in developed nations. However, there are no effective treatments.

Now, in a study published in Blood, researchers have developed a monoclonal antibody that is showing promise as a new therapy for patients. And in a Nature Communications study, the same team discovered a signaling pathway that may be mediating fibrosis and could be a target for future therapies.

Masahiro Hara

After graduating from Hosei University, Hara worked at Denso, a Toyota Group subsidiary, where he began developing a barcode system. [ 6 ] In 1992, at Denso’s development department (later Denso Wave), he was tasked with creating a new 2D code to efficiently track automotive components. [ 7 ] [ 8 ] [ 9 ] [ 10 ] One day during a lunchtime game of go, he realized the black-and-white patterns could encode information. [ 6 ] He also researched publications to find a unique proportion for the position pattern to ensure readability. [ 11 ] The code was introduced in 1994. [ 12 ]

In 2021, QR codes were being used to book and track COVID-19 tests and contact tracing. [ 6 ] Hara has stated that he would like to develop QR codes for additional medical purposes, including imaging such as x-rays or electrocardiogram data. [ 2 ] Hara still works for Denso as of 2024. [ 1 ]

[ edit ].

Researchers reveal intricate control system for key immune gene

The immune system faces a delicate balancing act: It must be aggressive enough to fight infections and cancer, yet restrained enough to avoid attacking the body’s own tissues.

More than two decades ago, researchers identified a gene called FOXP3 as playing a critical role in maintaining this balance and preventing autoimmune disease—work that garnered this year’s Nobel Prize in Physiology or Medicine.

Now, scientists at Gladstone Institutes and UC San Francisco (UCSF) have mapped the intricate network of genetic switches that use to fine-tune levels of FOXP3. Their findings, published in Immunity, have important implications for developing immune therapies and address a long-standing mystery about why this gene behaves differently in humans than in mice.

/* */