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Category: biotech/medical – Page 24

🔬Binary Fission Uncovered: DNA Relay-Ratchet Mechanism + Septum Formation!

In this video, we take a deep dive into the fascinating process of binary fission, the primary mode of reproduction in prokaryotic cells like bacteria.

You’ll learn how:
🧬 DNA replication begins the cycle.
⚙ The DNA relay-ratchet mechanism ensures accurate segregation of chromosomes, and.
đŸ§± A septum forms to physically divide the cell into two genetically identical daughter cells.

Whether you’re a student, teacher, or just curious about microbiology, this simplified explanation breaks down complex concepts into clear, visual steps.

📚 References & Further Reading:
https://courses.lumenlearning.com/sun
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https://media.springernature.com/full


✹ Support EasyPeasy!
Get early access, behind-the-scenes content, and suggest future topics:
👉 / @easypeasylearning.
👉 / supereasypeasy.
🔔 Don’t forget to like, subscribe, and hit the bell so you never miss a new video!

Gene-editing system targets multiple organs simultaneously

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a new study shows.

Gene-editing nanoparticle system targets multiple organs simultaneously

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a new study shows. The findings, published in Nature Biotechnology, could lead to new therapies for a variety of genetic diseases that affect multiple organs.

“Multi-organ diseases may need to be treated in more than one place. The development of multi-organ-targeted therapeutics opens the door to realizing those opportunities for this and other diseases,” said study leader Daniel Siegwart, Ph.D., Professor of Biomedical Engineering, Biochemistry, and in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern.

Gene editing—a group of technologies designed to correct disease-causing mutations in the genome—has the potential to revolutionize medicine, Dr. Siegwart explained. Targeting these technologies to specific organs, tissues, or will be necessary to effectively and safely treat patients.

Artificial neural networks reveal how peripersonal neurons represent the space around the body

The brains of humans and other primates are known to execute various sophisticated functions, one of which is the representation of the space immediately surrounding the body. This area, also sometimes referred to as “peripersonal space,” is where most interactions between people and their surrounding environment typically take place.

Researchers at Chinese Academy of Sciences, Italian Institute of Technology (IIT) and other institutes recently investigated the neural processes through which the brain represents the area around the body, using brain-inspired computational models. Their findings, published in Nature Neuroscience, suggest that receptive fields surrounding different parts of the body contribute to building a modular model of the space immediately surrounding a person or (AI) agent.

“Our journey into this field began truly serendipitously, during unfunded experiments done purely out of curiosity,” Giandomenico Iannetti, senior author of the paper, told Medical Xpress. “We discovered that the hand-blink reflex, which is evoked by electrically shocking the hand, was strongly modulated by the position of the hand with respect to the eye.

Herpes virus reshapes the human genome for its own benefit, but a single enzyme can stop it

Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the host’s cellular machinery to make new copies of themselves. Herpes simplex virus-1 (HSV-1), it turns out, also redecorates, according to a study in Nature Communications.

Researchers at the Center for Genomic Regulation (CRG) in Barcelona have discovered the cold sore reshapes the human genome’s architecture, rearranging its shape in three-dimensional space so that HSV-1 can access host genes most useful for its ability to reproduce.

“HSV-1 is an opportunistic interior designer, reshaping the human genome with great precision and choosing which bits it comes into contact with. It’s a novel mechanism of manipulation we didn’t know the virus had to exploit host resources,” says Dr. Esther González Almela, first author of the study.

Researcher’s lifelong work sheds light on neurodegenerative diseases caused by errors in cellular protein production

One of the great biological mysteries of the human body is how hundreds of complex, origami-like proteins, many of which are crucial for normal body function, come to assume their final, correct shape.

New all-silicon computer vision hardware advances in-sensor visual processing technology

Researchers at the University of Massachusetts Amherst have pushed forward the development of computer vision with new, silicon-based hardware that can both capture and process visual data in the analog domain. Their work, described in the journal Nature Communications, could ultimately add to large-scale, data-intensive and latency-sensitive computer vision tasks.

“This is very powerful retinomorphic hardware,” says Guangyu Xu, associate professor of electrical and engineering and adjunct associate professor of biomedical engineering at UMass Amherst. “The idea of fusing the sensing unit and the processing unit at the device level, instead of physically separating them apart, is very similar to the way that process the visual world.”

Existing computer vision systems often involve exchanging redundant data between physically separated sensing and computing units.