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Category: biotech/medical – Page 21

Cardiovascular Disease Risk Biomarker Analysis (70+ Tests Since 2005)

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Tiny protein dismantles the toxic clumps behind Alzheimer’s

St. Jude Children’s Research Hospital. (2025, August 23). Tiny protein dismantles the toxic clumps behind Alzheimer’s. ScienceDaily. Retrieved August 23, 2025 from www.sciencedaily.com/releases/2025/08/250822073817.htm.

St. Jude Children’s Research Hospital. “Tiny protein dismantles the toxic clumps behind Alzheimer’s.” ScienceDaily. www.sciencedaily.com/releases/2025/08/250822073817.htm (accessed August 23, 2025).

Under or over? Automated technique can visualize and measure DNA tangles

At school, it’s often presented as a tidy double helix but scientists are revealing the varied and intricate shapes of DNA molecules.

DNA is a molecule found in just about every . Because the molecule is long, it ends up twisting on itself and getting tangled. Enzymes in the body try to regulate this process but when that fails, normal activity in the cell can be disrupted, which triggers ill health and could be a factor in diseases such as cancer and neurodegeneration.

To find cures for major illnesses, scientists need to understand the complex shape of DNA tangles. Existing lab techniques enable them to plot the shape and structure of DNA tangles, but it is laborious and time-consuming.

400 Years After Their Discovery, Red Blood Cells Continue To Astonish Scientists

Penn researchers have revealed that red blood cells, not just platelets, play an active role in clot contraction. For years, scientists believed that red blood cells simply tagged along during clot formation without doing much. A new study from the University of Pennsylvania now shows they play an

In our lab we developed a novel nano-thermometer based on a superconducting quantum interference device (tSOT: SQUID on Tip thermometer) with a diameter of less than 50 nanometres that resides at the apex of a sharp pipette

This tool provides scanning cryogenic thermal sensing that is 4 orders of magnitude more sensitive than previous devices allowing the detection of a sub 1 μK temperature difference. Furthermore, it is non-contact and non-invasive and allows thermal imaging of very low intensity, nanoscale energy dissipation down to the fundamental Landauer limit of 40 femtowatts for continuous readout of a single qubit at one gigahertz at 4.2 kelvin.

Modelling the Complexity of Human Skin In Vitro

The skin serves as an important barrier protecting the body from physical, chemical and pathogenic hazards as well as regulating the bi-directional transport of water, ions and nutrients. In order to improve the knowledge on skin structure and function as well as on skin diseases, animal experiments are often employed, but anatomical as well as physiological interspecies differences may result in poor translatability of animal-based data to the clinical situation. In vitro models, such as human reconstructed epidermis or full skin equivalents, are valuable alternatives to animal experiments. Enormous advances have been achieved in establishing skin models of increasing complexity in the past. In this review, human skin structures are described as well as the fast evolving technologies developed to reconstruct the complexity of human skin structures in vitro.

Hemoglobin’s antioxidant role in brain cells points to new therapeutic avenue

Hemoglobin, long celebrated for ferrying oxygen in red blood cells, has now been revealed to play an overlooked—and potentially game-changing—antioxidant role in the brain.

In such as (ALS), Parkinson’s, Alzheimer’s, and aging, brain cells endure relentless damage from the aberrant (or excessive) (ROS). For decades, scientists have tried to neutralize ROS with antioxidant drugs, but most failed: they couldn’t penetrate the brain effectively, were unstable, or indiscriminately damaged healthy cells.

This new study, led by Director C. Justin Lee of the Center for Cognition and Sociality within the Institute for Basic Science (IBS) in Daejeon, South Korea, set out to identify the brain’s own defenses against a particularly harmful form of ROS—hydrogen peroxide (H2O2). The study has been published in Signal Transduction and Targeted Therapy.

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