Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: biotech/medical – Page 225

Summary: Researchers have isolated the electrical activity of individual neurons in the vagus nerve responsible for regulating cardiovascular function in humans. By identifying neurons that fire in sync with the heartbeat, scientists can now study how these neurons monitor or control heart activity.

This breakthrough could lead to new insights into how cardiovascular diseases develop and why vagal neuron activity changes in these conditions. The findings offer a foundation for exploring therapeutic targets in heart disease by studying vagus nerve activity in both healthy individuals and those with cardiovascular issues.

Read more | >

Summary: Sound stimulation can manipulate brain waves during REM sleep, a stage crucial for memory and cognition. Using advanced technology, researchers were able to increase the frequency of brain oscillations that slow down in dementia patients, potentially improving memory functions.

The non-invasive technique could pave the way for innovative treatments for dementia by targeting brain activity during sleep. This approach offers hope for enhancing memory and cognition with minimal disruption to patients’ lives.

Read more | >

MIT researchers have developed a miniature, chip-based “tractor beam,” like the one that captures the Millennium Falcon in the film “Star Wars,” that could someday help biologists and clinicians study DNA, classify cells, and investigate the mechanisms of disease.

Small enough to fit in the palm of your hand, the device uses a beam of light emitted by a silicon-photonics chip to manipulate particles millimeters away from the chip surface. The light can penetrate the glass cover slips that protect samples used in biological experiments, enabling cells to remain in a sterile environment.

Traditional optical tweezers, which trap and manipulate particles using light, usually require bulky microscope setups, but chip-based optical tweezers could offer a more compact, mass manufacturable, broadly accessible, and high-throughput solution for optical manipulation in biological experiments.

Read more | >

Summary: Neural stem cells, which create new neurons in the brain, become less active with age due to elevated glucose levels. Researchers found that by knocking out the glucose transporter gene GLUT4 in older mice, they could significantly increase the production of new neurons.

This discovery opens up potential pathways for both genetic and behavioral interventions to stimulate brain repair, including the possibility of a low-carbohydrate diet. The findings could help treat neurodegenerative diseases and aid in brain recovery after injury.

Read more | >

Scientists at the University of Minnesota and the Midwest Antiviral Drug Discovery (AViDD) Center have made a surprising discovery: antibodies can have opposite effects on viral infections in human cells.

The spike protein of SARS-CoV-2, the virus that causes COVID-19, enables the virus to enter human cells and is the primary target for the body’s antibodies. Previous research has shown that antibodies can either block the virus, have no effect, or, in rare cases, assist the virus in infecting cells. While antibody drugs work to block infections, this new study challenges current understanding of their mechanisms.

Published in the journal PLOS Pathogens, this study is the first to identify an antibody that can both assist and block the virus. This particular antibody helps pre-omicron variants of the virus infect cells while preventing the omicron variant from doing the same. The study also explains how the antibody aids the pre-omicron virus in invading cells while blocking the omicron virus from succeeding.

Read more | >

Patients with certain mental disorders, including schizophrenia, often hear voices in the absence of sound.

Auditory hallucinations are likely the result of abnormalities in two brain processes: a broken corollary discharge that fails to suppress self-generated sounds, and a noisy efference copy that makes the brain hear these sounds more intensely than it should. That is the conclusion of a study published October 3 in the open-access journal PLOS Biology by Xing Tian, of New York University Shanghai, China, and colleagues.

In the new study, researchers carried out electroencephalogram (EEG) experiments measuring the brain waves of 20 patients diagnosed with schizophrenia with and 20 patients diagnosed with who had never experienced such hallucinations.

Read more | >

🧠 Neuromodulation through the eyes 👀

Neuroplasticity, also known as neural plasticity or brain plasticity, is a process that involves adaptive structural and functional changes to the brain.

Founded and directed by Deborah Zelinsky, O.D., F.N.O.R.A., F.C.O.V.D.

Just as with eye-hand coordination, integration of vision and sound – eye-ear connection – must be developed. If the two senses are out of sync, a person can experience difficulties in academics, social situations and activities such as sports.

Balance between vision and hearing is necessary for a person to learn letter sounds, for example, while applying those sounds to the words they see on a page. In social situations, a person can better understand what another is saying – and meaning — by watching body language and facial expression. Autistic patients cannot discern the nuances of a joke because they simply listen. They do not connect sound and vision, because the environment around them is too confusing.

A student whose eyesight is more sensitive than his or her hearing may be easily distracted by activities and moving objects in the environment and unable to concentrate on what the teacher is saying. People whose peripheral vision is not sufficiently “tuned in” may have to turn their head before finding what is causing a certain sound.

Continue reading “The Z-Bell℠ Test: A Breakthrough in Eye-Ear Testing” | >