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Implantable bioelectronics and wearable sensors for kidney health and disease

Advances in biosensor technology have the potential to enable continuous, non-invasive monitoring of kidney health through wearable and implantable systems. Non-invasive microfluidic systems have demonstrated utility in the detection of kidney-relevant biomarkers in peripheral body fluids such as sweat, interstitial fluid, tears and saliva, whereas implantable systems permit the direct measurement of biophysical tissue properties including tissue oxygenation, perfusion and temperature.

Heavy Drinkers Face Higher Risk of Brain Lesions And Alzheimer’s Markers

Alcohol is notoriously bad for health, and a recent study might add “long-term effects on brain health” to the growing list of ways drinking can cause harm.

The research, led by scientists at the University of São Paulo in Brazil, investigated the impact of regular drinking by examining brain autopsy data from 1,781 individuals, correlating findings with their reported drinking habits.

After adjusting for sociodemographic and clinical variables, like smoking and physical activity, the team found that the heaviest drinkers had a 133 percent higher risk of developing vascular brain lesions compared to non-drinkers.

High-performance memory devices can dissolve in water to address e-waste problem

The use of electronics in various forms is on the rise, from wearable devices like smartwatches to implantable devices like body-implanted sensors, skin-worn smart patches, and disposable monitoring devices. These devices, which are inevitably discarded after use, contribute to the growing problem of electronic waste (e-waste), a significant environmental concern.

The Korea Institute of Science and Technology (KIST) has announced that a joint research team, led by Dr. Sangho Cho of the Center for Extreme Materials Research and Dr. Yongho Joo of the Center for Functional Composite Materials Research, has developed a that offers high-performance data storage while completely degrading within days when immersed in water. The research is published in the journal Angewandte Chemie International Edition.

The material is biocompatible and stable enough for implantation in the human body, and the onset of degradation can be controlled by adjusting the thickness and the composition of the protective layer. Once this protective layer dissolves, the material degrades naturally in water within approximately three days, without leaving any residue.

Creatine monohydrate pilot in Alzheimer’s: Feasibility, brain creatine, and cognition

Preclinical studies suggest that creatine monohydrate (CrM) improves cognition and Alzheimer’s disease (AD) biomarkers. However, there is currently no clinical evidence demonstrating the effects of CrM in patients with AD.

Diabetes drug may serve as alternative treatment option for hydrocephalus

A drug commonly used to treat type 2 diabetes may reduce excess fluid in the brains of patients with hydrocephalus, which could help treat the disease less invasively than current treatments, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.

Stephen Magill, MD, Ph.D., assistant professor of Neurological Surgery, was senior author of the study.

Normal pressure occurs when excess cerebrospinal fluid builds up inside the skull and puts pressure on the brain. The cause of the condition is elusive and affects up to 3% of individuals over the age of 65, with symptoms including , difficulty walking and bladder problems.

Nanodomains hold the key to next-generation solar cells, researchers find

A new study, published in Nature Nanotechnology and featured on the journal’s front cover this month, has uncovered insights into the tiny structures that could take solar energy to the next level.

Researchers from the Department of Chemical Engineering and Biotechnology (CEB) have found that dynamic nanodomains within lead halide perovskites—materials at the forefront of solar cell innovation—hold a key to boosting their efficiency and stability. The findings reveal the nature of these microscopic structures, and how they impact the way electrons are energized by light and transported through the material, offering insights into more efficient solar cells.

The study was led by Milos Dubajic and Professor Sam Stranks from the Optoelectronic Materials and Device Spectroscopy Group at CEB, in collaboration with an international network, with key contributions from Imperial College London, UNSW Sydney, Colorado State University, ANSTO Sydney, and synchrotron facilities in Australia, the UK, and Germany.

Mist and sea spray create unique conditions for urea to form from simple gases

Urea is considered a possible key molecule in the origin of life. ETH researchers have discovered a previously unknown way in which this building block can form spontaneously on aqueous surfaces without the need for any additional energy.

Urea is one of the most important industrial chemicals produced worldwide. It is used as a fertilizer, for the production of synthetic resins and explosives and as a fuel additive for cleaning car exhaust gases. Urea is also believed to be a potential key building block for the formation of biological molecules such as RNA and DNA in connection with the question of the origin of life.

Until now, the origin of urea itself on early Earth has not been conclusively clarified.

Turning tap water into hydrogen: New strategy lets PEM electrolyzers use impure water

In recent years, energy engineers have been working on a wide range of technologies that could help to generate and store electrical power more sustainably. These include electrolyzers, devices that could use electricity sourced via photovoltaics, wind turbines or other energy technologies to split water (H2O) into hydrogen (H2) and oxygen (O2), via a process known as electrolysis.

The hydrogen produced by electrolyzers could in turn be used in fuel cells, devices that convert the chemical energy in hydrogen into electricity without combustion and could be used to power trucks, buses, forklifts and various other heavy vehicles, or could provide back-up power for hospitals, data centers and other facilities.

Many recently designed electrolyzers prompt the splitting of water into hydrogen using a (PEM), a membrane that selectively allows protons (H+) to pass through, while blocking gases.

New study identifies brain networks underlying psychopathy

A recent study has shed light on the brain structure differences associated with psychopathy—a condition known to be one of the strongest predictors of persistent violent behavior.

The findings are published in the journal European Archives of Psychiatry and Clinical Neuroscience.

Using advanced neuroimaging and the Julich-Brain Atlas, researchers from Forschungszentrum Jülich, RWTH Aachen University, Heinrich-Heine-University Düsseldorf, Georg August University, (Germany) and University of Pennsylvania (U.S.) have identified specific brain networks that appear to be structurally altered in individuals exhibiting . The Atlas can be freely accessed via the EBRAINS Research Infrastructure.