Predicting how proteins bind to other molecules could revolutionize biochemistry, drug discovery.
The authors of a new study were able to order all the synthetic genes necessary to reconstruct the 1918 pandemic influenza virus. Do their findings represent a security flaw in a critical area of biotechnology?
Colin Jacobs, PhD, assistant professor in the Department of Medical Imaging at Radboud University Medical Center in Nijmegen, The Netherlands, and Kiran Vaidhya Venkadesh, a second-year PhD candidate with the Diagnostic Image Analysis Group at Radboud University Medical Center discuss their 2021 Radiology study, which used CT images from the National Lung Cancer Screening Trial (NLST) to train a deep learning algorithm to estimate the malignancy risk of lung nodules.
The bird flu crisis on dairy farms could boost interest in milk protein manufactured in microorganisms and plants.
HiDEF-seq advances cancer treatment:
HiDEF-seq technique could further help develop or advance new prevention approaches or develop treatments for genetic diseases and even cancer.
Continue reading “New DNA sequencing technique detects early genetic mutations” »
The DNA a woman is born with may influence how her cells respond to chromosomal abnormalities acquired with aging, according to a new genomic analysis co-led by NCI researchers.
FDA has granted an accelerated approval to tovorafenib (Ojemda) for kids and teens who have low-grade glioma with changes in the BRAF gene.
Although very rare, past reports show some cancer patients may develop secondary cancers following lifesaving CAR T-cell therapy.
This protocol details the generation of cortical organoids with complex neural oscillations through a ‘semi-guided’ protocol, and their functional characterization using microelectrode array measurements, calcium imaging and adeno-associated virus transduction.
The reason targeted treatment for non-small cell lung cancer fails to work for some patients, particularly those who have never smoked, has been discovered by researchers from UCL, the Francis Crick Institute and AstraZeneca.
The study, published in Nature Communications, shows that lung cancer cells with two particular genetic mutations are more likely to double their genome, which helps them to withstand treatment and develop resistance to it.
In the UK, lung cancer is the third most common type of cancer and the leading cause of cancer death. Around 85% of patients with lung cancer have non-small cell lung cancer (NSCLC), and this is the most common type found in patients who have never smoked. Considered separately, “never smoked” lung cancer is the fifth-most common cause of cancer death in the world.
