10 years ago we saw a breakthrough in modern biology.
An American scientist discovered that manipulation of the Cas9 protein resulted in a gene technology worthy of a sci-fi film: CRISPR.
Think of it as a pair of molecular scissors capable of cutting and editing the DNA of humans, animals, plants, bacteria and viruses.
Researchers from the Chinese Academy of Sciences‘Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) have recently found two fossil repositories in the early Silurian strata of southwest Guizhou and Chongqing that are rewriting the “from fish to human” evolutionary story.
Four different papers describing their findings were recently published in the journal Nature.
Humans are one of the 99.8% of species of extant vertebrates that are gnathostomes, or jawed vertebrates. The basic body plan and several key organs of humans can be traced back to the origin of gnathostomes. One of the most significant developments in the evolution of vertebrates is the emergence of jaws.
Rheumatoid arthritis affects 1 in 100 people worldwide. It causes inflamed, painful and swollen joints, often in the hands and wrists, and can lead to loss of joint function as well as chronic pain and joint deformities and damage. What causes this condition has been unknown.
In our recently published study, my colleagues and I found an important clue to a potential culprit behind this disease: the bacteria in your gut.
GENEVA (AP) — The number of people infected with tuberculosis, including the kind resistant to drugs, rose globally for the first time in years, according to a report Thursday by the World Health Organization.
The U.N. health agency said more than 10 million people worldwide were sickened by tuberculosis in 2021, a 4.5% rise from the year before. About 1.6 million people died, it said. WHO said about 450,000 cases involved people infected with drug-resistant TB, 3% more than in 2020.
Dr. Mel Spigelman, president of the non-profit TB Alliance, said more than a decade of progress was lost when COVID-19 emerged in 2020.
Two lots of quinapril and hydrochlorothiazide tablets have been recalled due to the presence of nitrosamines, according to a notice posted on the Food and Drug Administration’s website.
Nitrosamines are common in water and foods, including cured and grilled meats, dairy products and vegetables and may increase the risk of cancer if people are exposed to them above acceptable levels over long periods of time.
The pink, round tablets contain 20 milligrams of quinapril and 12.5 milligrams of hydrochlorothiazide and are supplied in 90-count bottles with an expiration date of January 2023. The drug is used to treat hypertension and lower blood pressure.
Summary: Researchers have developed a new ophthalmological device that can detect degenerative visual problems such as age-related macular degeneration long before the onset of the first symptoms.
Source: EPFL
Researchers at an EPFL lab have developed an ophthalmological device that can be used to diagnose some degenerative eye disorders long before the onset of the first symptoms. In early clinical trials, the prototype was shown to produce images with a sufficient degree of precision in just five seconds.
Discovery made possible by state-of-the-art imaging and more than 60 million worms.
For the first time and in near-atomic detail, scientists at Oregon Health & Science University (OHSU) have revealed the structure of the key part of the inner ear responsible for hearing.
“This is the last sensory system in which that fundamental molecular machinery has remained unknown,” said senior author Eric Gouaux, Ph.D. He is a senior scientist with the OHSU Vollum Institute and a Howard Hughes Medical Institute investigator. “The molecular machinery that carries out this absolutely amazing process has been unresolved for decades.”
The first-in-human trial of FLASH radiotherapy found the experimental treatment to be safe and effective — suggesting that there may be a faster, less painful way to use radiation against cancer.
The status quo: Radiation therapy is a common cancer treatment that uses high doses of radiation to kill or slow the growth of cancer cells. Usually, this is done by aiming a beam of radiation directly at a tumor for a few minutes. This part of the process is painless, like getting an X-ray.
Patients typically undergo daily treatments five days a week for several weeks, and including setup time, a treatment usually takes about 15 to 30 minutes.
Concern is rising over the ongoing Ebola outbreak in Uganda that is now swiftly spreading in the densely populated capital city of Kampala. The outbreak is caused by a lesser-seen species of Ebolavirus, the Sudan virus, for which there is no proven vaccine or treatment.
Uganda’s Ministry of Health declared an outbreak on September 20, a day after a 24-year-old man from a rural area in central Uganda died of the disease. Since then, the virus has spread to seven districts in the country, with the ministry reporting a total of 109 confirmed cases and 30 deaths. Health workers accounted for 15 of the confirmed cases and six of the confirmed deaths. There are also unofficial reports of probable cases and deaths.
Health experts are particularly concerned about the spread into Kampala, which government officials reported only Sunday. As of Wednesday, the city of more than 1.6 million has seen at least 15 confirmed cases. Of the 15 cases, six are school-age children from the same family.