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The ZyCoV-D vaccine is also the world’s first DNA vaccine against Covid-19.

Like other vaccines, a DNA vaccine, once administered, teaches the body’s immune system to fight the real virus.

ZyCoV-D uses plasmids — or small rings of DNA that contain genetic information — to deliver the jab between two layers of the skin.

ZyCov-D is also India’s first needle-free Covid-19 jab.

It is administered with a disposable needle-free injector, which uses a narrow stream of the fluid to penetrate the skin and deliver the jab to the proper tissue.

A new computer model demonstrates that vaccinations have impacts well beyond just preventing disease and death: they can also slow the spread of antimicrobial resistance.

Pneumococcal diseases—which include illnesses ranging from inner ear infections to pneumonia and meningitis—are a leading cause of death globally among children under five. While there are effective vaccines against pneumococcal diseases, access is still a challenge for populations in low-income—and some middle income—countries. And antimicrobial resistance to the antibiotics commonly used to treat these infections is a growing problem.

“We wanted to the value of vaccinating—not only to show that vaccination reduces death or disability from these diseases, but also to quantify whether vaccination can slow antimicrobial resistance,” says Andrew Stringer, an assistant professor of veterinary and global health at NC State.

The Israeli mask company Sonovia has released a report from a leading Italian textile-testing laboratory showing that its fabric eliminates the COVID-19 Delta variant particles with over 99.95% effectiveness.


The lab is next expected to test the fabric against the MU strain, which carries several mutations to the spike gene, and is labeled a “variant of interest” by the World Health Organization, said Sonovia Chief Technology Officer Liat Goldhammer-Steinberg.

The MU strain has not yet entered Israel, according to any official reports, but Health Ministry officials have warned of its potential negative impact.

VisMederi is a commercial research laboratory located in Italy. It says on its website that the company “currently receives orders worldwide in the field of vaccines, where it conducts analytical testing of biological samples and validation of bioanalytical methods for the pharmaceutical industry.”

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Levine’s Biological age calculator is embedded as an Excel file in this link:

Quantifying Biological Age

Papers referenced in the video:
The baseline levels and risk factors for high-sensitive C-reactive protein in Chinese healthy population.
https://immunityageing.biomedcentral.com/articles/10.1186/s1…0126-7

Commonly used clinical chemistry tests as mortality predictors: Results from two large cohort studies.

O,.o.


Studying transitions in and out of the altered state of consciousness caused by intravenous (IV) N, N-Dimethyltryptamine (DMT — a fast-acting tryptamine psychedelic) offers a safe and powerful means of advancing knowledge on the neurobiology of conscious states. Here we sought to investigate the effects of IV DMT on the power spectrum and signal diversity of human brain activity (6 female, 7 male) recorded via multivariate EEG, and plot relationships between subjective experience, brain activity and drug plasma concentrations across time. Compared with placebo, DMT markedly reduced oscillatory power in the alpha and beta bands and robustly increased spontaneous signal diversity. Time-referenced and neurophenomenological analyses revealed close relationships between changes in various aspects of subjective experience and changes in brain activity.

An inexpensive oral anti-depressant can save the lives of COVID-19 patients and cut hospital admissions by up to 30 per cent, says a study co-led by McMaster University.

McMaster researcher Ed Mills and his team treated 738 randomly selected Brazilian COVID-19 patients with fluvoxamine, with another 733 received a placebo, between Jan. 20 to Aug. 6 of this year.

Every patient receiving fluvoxamine during the trial is tracked for 28 days to determine their health outcomes and if they still need hospital treatment. They found about a 30% reduction in events among those receiving fluvoxamine and those that did not.


It’s neither a bird nor a plane, but a winged microchip as small as a grain of sand that can be carried by the wind as it monitors such things as pollution levels or the spread of airborne diseases.


Northwestern University says these are the world’s smallest human-made flying structures, and they could be used for monitoring the environment, population surveillance or disease tracking.

“Our study points to sex-and environment-specific effects of a common genetic variant. In the mice, we observed that Ghrd3 leads to a ‘female-like’ expression pattern of dozens of genes in male livers under calorie restriction, which potentially leads to the observed size reduction,” Saitou says.

“Females, already smaller in size, may suffer from negative evolutionary consequences if they lose body weight. Thus, it is a reasonable and also very interesting hypothesis that a genetic variant that may affect response to nutritional stress has evolved in a sex-specific manner,” Mu says.


A new study delves into the evolution and function of the human growth hormone receptor gene, and asks what forces in humanity’s past may have driven changes to this vital piece of DNA.

The research shows, through multiple avenues, that a shortened version of the gene—a known as GHRd3—may help people survive in situations where resources are scarce or unpredictable.