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Category: biotech/medical – Page 1,337

AI could revolutionize healthcare but can we trust it?

The tool can identify symptoms of dengue, malaria, leptospirosis, and scrub typhus.

The study investigates both statistical and machine learning approaches. WHO has categorized dengue as a “neglected tropical disease.”

A prediction tool based on multi-nominal regression analysis and a machine learning algorithm was developed.

Accurate diagnosis is essential for the proper treatment and ensuring the well-being of patients. However, some diseases present with similar clinical symptoms and laboratory results, making diagnosing them more challenging.

Artificial Intelligence is perhaps the most promising technology for transforming our lives — but it’s also incredibly scary. At CES 2022, A panel of AI experts discussed what role AI might play in the future of healthcare.

In a session titled “Consumer Safety Driven by AI,” Pat Baird, an AI engineer and software developer who works in standards and regulations for Phillips, and Joseph Murphy, VP Marketing at Sensory Inc., an American technology company that develops AI products, discussed what AI could add to our lives. They also discussed the apprehension many people feel about the technology.

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Artificial womb possibility

Biomedical researchers working with lambs got promising results from an experiment designed to prevent the health problems associated with premature births.

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Scientists Grow “Synthetic” Embryo With Brain and Beating Heart — Without Eggs or Sperm

We have arrived at Aldous Huxleys Brave new world.

Scientists from the University of Cambridge have created model embryos from mouse stem cells that form a brain, a beating heart, and the foundations of all the other organs of the body. It represents a new avenue for recreating the first stages of life.

The team of researchers, led by Professor Magdalena Zernicka-Goetz, developed the embryo model without eggs or sperm. Instead, they used stem cells – the body’s master cells, which can develop into almost any cell type in the body.

“It’s just unbelievable that we’ve got this far. This has been the dream of our community for years, and major focus of our work for a decade and finally we’ve done it.” —

Metformin & Rapamycin Show Combined Benefits in New Study

They boost each other and block side effects? (In mice)

Rapamycin and metformin are viewed by many as the two most promising anti-aging drugs, but now scientists have found that these drugs can work hand in hand and show combined benefits, boosting each other’s effectiveness and blocking side effects — or at least that’s what we’ve seen in mice.

When tested by the Intervention Testing Program metformin failed to significantly increase lifespan in mice. However, in combination with rapamycin, it worked synergistically, leading to a drastic increase in median and maximal lifespan.

In this new study, the researchers put the “combination hypothesis” to the test again, using male mice of a common pre-diabetes model. The mice received either rapamycin, metformin, or a combination from 12 to 30 weeks of age.

Being pre-diabetic, these mice usually gain a lot of weight with age. Metformin treatment did not alleviate this trend, but both the rapamycin and combination treatments allowed the mice to maintain normal weight until the end of the experiment.

Continue reading “Metformin & Rapamycin Show Combined Benefits in New Study” | >

Scientists Just Genetically Edited a Million Years of Evolution Into Mouse DNA

O.o!!!!!

Changing the number of chromosomes an animal has can take millions of generations to happen in nature through the course of evolution – and now, scientists have been able to make these same changes in lab mice in a relative blink of an eye.

The new technique using stem cells and gene editing is a major accomplishment, and one that the team is hoping will reveal more about how the rearrangement of chromosomes can influence the way that animals evolve over time.

It’s in chromosomes – those strings of protein and DNA inside cells – that we find our genes, inherited from our parents and blended together to make us who we are.

Simple Gene Circuits Hint at How Stem Cells Differentiate

Mathematical models suggest that with just a few more genes, it might be possible to define hundreds of cellular identities, more than enough to populate the tissues of complex organisms. It’s a finding that opens the door to experiments that could bring us closer to understanding how, eons ago, the system that builds us was built.

The Limits of Mutual Repression

Developmental biologists have illuminated many tipping points and chemical signals that prompt cells to follow one developmental pathway or another by studying natural cells. But researchers in the field of synthetic biology often take another approach, explained Michael Elowitz, a professor of biology and bioengineering at Caltech and an author of the new paper: They build a system of cell-fate control from scratch to see what it can tell us about what such systems require.

Recently Discovered Molecule Kills Hard-To-Treat Cancers

A new molecule created by a researcher at the University of Texas at Dallas kills a variety of difficult-to-treat cancers, including triple-negative breast cancer, by taking advantage of a weakness in cells that was not previously targeted by existing drugs.

The research, which was conducted using isolated cells, human cancer tissue, and mouse-grown human cancers, was recently published in Nature Cancer.

A co-corresponding author of the study and an associate professor of chemistry and biochemistry in the School of Natural Sciences and Mathematics at the University of Texas at Dallas, Dr. Jung-Mo Ahn has dedicated more than ten years of his career to developing small molecules that target protein-protein interactions in cells. He previously created potential therapeutic candidate compounds for treatment-resistant prostate cancer and breast cancer using a method called structure-based rational drug design.

Highly Sensitive, Mass Producible Organic Photodetectors for Medical Sensors, Fingerprint Recognition

New green-light absorbing photodetectors could be useful for medical sensors, fingerprint recognition, and more.

New green-light absorbing transparent organic photodetectors that are highly sensitive and compatible with CMOS fabrication methods have been developed and demonstrated by researchers. Incorporating these new photodetectors into organic-silicon hybrid image sensors could be useful for many applications. These include light-based heart-rate monitoring, fingerprint recognition, and devices that detect the presence of nearby objects.

Whether used in scientific cameras or smartphones, most of today’s imaging sensors are based on CMOS technology and inorganic photodetectors that convert light signals into electric signals. Although photodetectors made from organic materials are attracting attention because they can help boost sensitivity, for example, it has thus far proven difficult to fabricate high-performance organic photodetectors.