Archive for the ‘biotech/medical’ category: Page 118
Mar 15, 2024
Cell Self-Destruction (Programmed Cell Death), Immunonutrition and Metabolism
Posted by Shubham Ghosh Roy in categories: biotech/medical, life extension
LatestPaper “Exploring beyond Common Cell Death Pathways in Oral Cancer: A Systematic Review” is now available.
Special Issue in journal Biology: Cell Self-Destruction (Programmed Cell Death), Immunonutrition and Metabolism.
Mar 15, 2024
Mapping the heart’s cellular blueprint: New insights into cardiac structure and disease repair
Posted by Shubham Ghosh Roy in category: biotech/medical
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Researchers unveil the complex cellular architecture of the heart using advanced RNA sequencing and imaging techniques, shedding light on the intricate organization of heart cells and their developmental pathways.
Mar 15, 2024
APOE from patient-derived astrocytic extracellular vesicles alleviates neuromyelitis optica spectrum disorder in a mouse model
Posted by Shubham Ghosh Roy in categories: biotech/medical, neuroscience
Analyzing cells from patients with neuromyelitis optica spectrum disorder, researchers show transfers of patient-derived extracellular vesicles rich in the apolipoprotein APOE alleviate neuroinflammation and slow astrocyte loss in a mouse model of this severe autoimmune disease.
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APOE was augmented in astrocytic extracellular vesicles from patients with neuromyelitis optica spectrum disorder and decreased brain lesions in a mouse model.
Mar 14, 2024
B cell depletion with anti-CD20 promotes neuroprotection in a BAFF-dependent manner in mice and humans
Posted by Shubham Ghosh Roy in categories: biotech/medical, neuroscience
Research involving mice and samples from patients with multiple sclerosis reveals how anti-CD20 antibodies such as ocrelizumab protect neurons in gray matter, and ties the treatment’s effects to elevated levels of BAFF.
Mar 14, 2024
Dr. William Kapp, MD — CEO, Fountain Life — Preventative, Predictive, Personalized Healthcare
Posted by Ira S. Pastor in categories: biotech/medical, chemistry, military
Preventative, predictive and personalized healthcare and longevity — dr. william kapp, MD — CEO, fountain life.
Dr. William Kapp, MD is Chief Executive Officer of Fountain Life (https://fountainlife.com/about/), a company focused on transforming the current healthcare system into one that is both proactive and data-driven, enabling enhanced longevity and catching and treating illnesses earlier than ever before, focusing on the detection and reversal of asymptomatic diseases and advancing an entirely new healthcare paradigm.
Mar 14, 2024
Paralyzed man walks again using only his thoughts
Posted by Shubham Ghosh Roy in categories: biotech/medical, neuroscience
“For 12 years I’ve been trying to get back my feet. Now I have learned how to walk normal, natural.”
A paralyzed man is walking again thanks to a “digital bridge” researchers created between his brain and a spinal stimulator.
“For 12 years I’ve been trying to get back my feet,” the 40-year-old Dutch man, Gert-Jan Oskam, told reporters on May 23. “Now I have learned how to walk normal, natural.”
Continue reading “Paralyzed man walks again using only his thoughts” »
Mar 14, 2024
Neurological conditions now leading cause of ill health and disability globally, new analysis finds
Posted by Saúl Morales Rodriguéz in categories: biotech/medical, life extension, neuroscience
Globally, the number of people living with, or dying from, neurological conditions such as stroke, Alzheimer’s disease and other dementias, and meningitis has risen substantially over the past 30 years due to the growth and aging of the global population as well as increased exposure to environmental, metabolic, and lifestyle risk factors. In 2021, 3.4 billion people experienced a nervous system condition, according to a major new analysis from the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2021, published in The Lancet Neurology.
The analysis suggests that worldwide, the overall amount of disability, illness, and premature death —a measurement known as disability-adjusted life years (DALYs)—caused by neurological conditions increased by 18% over the past 31 years, rising from around 375 million years of healthy life lost in 1990 to 443 million years in 2021.
The absolute number of DALYs is increasing in large part due to aging and growing populations worldwide.
Mar 14, 2024
Motixafortide and Stem Cell Transplants for Multiple Myeloma
Posted by Shubham Ghosh Roy in categories: biotech/medical, chemistry
The recently approved drug motixafortide may help improve stem cell transplants for people with multiple myeloma. Learn more about this treatment:
However, Dr. Schulz cautioned, this finding is not definitive because the two drugs were not tested head-to-head in a randomized trial. A randomized clinical trial comparing the drugs “would have been a better and fairer comparison,” he said, since plerixafor and motixafortide both work by blocking a chemical signal that tells stem cells to stay in the bone marrow.
Finally, Dr. Crees and his colleagues did a series of experiments looking at the different types of blood-forming stem cells mobilized by G-CSF plus placebo, motixafortide, or plerixafor.
Continue reading “Motixafortide and Stem Cell Transplants for Multiple Myeloma” »
Mar 14, 2024
Cell division, DNA repair and cancer progression closely tied to CDK9 dysfunction
Posted by Shubham Ghosh Roy in category: biotech/medical
Researchers describe a newly observed role for the protein Cyclin Dependent Kinase 9 (CDK9) in regulating DNA repair during cellular division, where errors can become the origin of cancerous tumor growth. Through a process called phosphorylation, the experiment simulated the interaction of CDK9 with the other proteins and genes involved in cell division and cancerous tumor growth.