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Category: biotech/medical – Page 1078

According to research conducted by the University of Pennsylvania, the enzyme DOT1L, a stem cell self-renewal factor, is necessary for mice to continue producing sperm throughout adulthood.

Men may continue to generate sperm throughout their adult life, in contrast to women who are born with all the eggs they will ever have. To do so, they must constantly renew the spermatogonial stem cells that give birth to sperm.

According to research by Jeremy Wang of the University of Pennsylvania School of Veterinary Medicine and colleagues, this stem cell renewal is dependent on a recently identified stem cell self-renewal factor known as DOT1L. The scientists demonstrated that animals lacking DOT1L are unable to retain spermatogonial stem cells, which affects their ability to constantly make sperm.

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Due to a rare genetic mutation, Aliria Rosa Piedrahita de Villegas should have had Alzheimer’s.

Alzheimer’s disease is a disease that attacks the brain, causing a decline in mental ability that worsens over time. It is the most common form of dementia and accounts for 60 to 80 percent of dementia cases. There is no current cure for Alzheimer’s disease, but there are medications that can help ease the symptoms.

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Hey it’s Han from WrySci-HX talking about how the anti diabetic drug Empagliflozin, brand name Jardiance, has reversed signs of vascular aging in mice! Is this why we’re seeing its benefits in humans? More below ↓↓↓

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Continue reading “FDA APPROVED Drug Reverses Vascular Aging in Mice!” | >

A group of international researchers has uncovered evidence of a super rare genetic condition that gives men an extra X chromosome, reporting the oldest clinical case of Klinefelter syndrome to date.

The evidence comes from a 1,000-year-old skeleton from Portugal.

Klinefelter syndrome is a where individuals are born with an extra copy of the X chromosome, occurring in approximately one in 1,000 genetic-male births.

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In a report this week from the science journal SciTechDaily, we learn of a scientific breakthrough that it clearly intended to be exciting and startling, but potentially worrisome as well. Scientists at the University of Cambridge have created a series of “model embryos” that include a functioning brain, a beating heart, and the foundation for all of the other bodily organs you would expect.

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As telemedicine has grown more popular, so have devices that allow people to measure their vital signs from home and transmit the results by computer to their doctors. Yet in many cases, obtaining accurate remote readings for people of color has proved a persistent challenge.

Take remote heart rate measurements, for example, which rely on a camera sensing subtle changes in the color of a patient’s face caused by fluctuations in the flow of blood beneath their skin. These devices, part of an emerging class of remote technologies, consistently have trouble reading color changes in people with darker skin tones, said Achuta Kadambi, an assistant professor of electrical and computer engineering at the UCLA Samueli School of Engineering.

Kadambi and his team have now developed a remote diagnostic technique that overcomes this against darker skin while also making heart rate readings more accurate for patients across the full range of skin tones. Their secret? Combining the light-based measurements of a camera with radio-based measurements from radar.

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The tool can identify symptoms of dengue, malaria, leptospirosis, and scrub typhus.

The study investigates both statistical and machine learning approaches. WHO has categorized dengue as a “neglected tropical disease.”

A prediction tool based on multi-nominal regression analysis and a machine learning algorithm was developed.

Accurate diagnosis is essential for the proper treatment and ensuring the well-being of patients. However, some diseases present with similar clinical symptoms and laboratory results, making diagnosing them more challenging.

Continue reading “AI could revolutionize healthcare but can we trust it?” | >

We have arrived at Aldous Huxleys Brave new world.

Scientists from the University of Cambridge have created model embryos from mouse stem cells that form a brain, a beating heart, and the foundations of all the other organs of the body. It represents a new avenue for recreating the first stages of life.

The team of researchers, led by Professor Magdalena Zernicka-Goetz, developed the embryo model without eggs or sperm. Instead, they used stem cells – the body’s master cells, which can develop into almost any cell type in the body.

“It’s just unbelievable that we’ve got this far. This has been the dream of our community for years, and major focus of our work for a decade and finally we’ve done it.” —

Continue reading “Scientists Grow “Synthetic” Embryo With Brain and Beating Heart — Without Eggs or Sperm” | >