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Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids Communications

Year 2021


Brain organoids derived from human pluripotent stem cells can model human brain development and disease, though current culture systems fail to ensure reliable production of high-quality organoids. Here the authors combine human brain extracellular matrix and culture in a microfluidic device to promote structural and functional maturation of human brain organoids.

Revolutionary gene-editing therapy treats girl’s “incurable” cancer

A U.K. teen with an aggressive form of leukemia is now cancer-free, thanks to a new gene-editing therapy.

The particular therapy used on the patient was only invented six years ago, and it’s now making doctors rethink the way doctors approach the disease.

Mike Drolet reports on how the revolutionary technology works, and the possibilities it offers to change the lives of those with types of cancer long-thought to be incurable.

For more info, please go to https://globalnews.ca/news/9086170/sean-thomas-legacy-toy-drive-bc/

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Throw Forward Thursday: CRISPR

The 2020 Nobel Prize for Chemistry was awarded to Dr. Jennifer Doudna and Dr. Emmanuelle Charpentier for their work on the gene editing technique known as CRISPR-Cas9. This gives us the ability to change the DNA of any living thing, from plants and animals to humans.

The applications are enormous, from improving farming to curing diseases. A decade or so from now, CRISPR will no doubt be taught in High Schools, and be a basic building block of medicine and agriculture. It is going to change everything.

There are ethical and moral concerns, of course, and we will need regulations to ensure this powerful technology is not abused. But we should focus on the remarkable opportunities CRISPR has opened up for us.

Details of cellular process which stops cancer developing revealed

Researchers have for the first time characterised the molecular mechanism of the early stages of programmed cell death or apoptosis, a process which plays a crucial role in the prevention of cancer.

The study, published today (2 June) in Science Advances, was led by Dr Luke Clifton at the Science and Technology Facilities Council (STFC) ISIS Neutron and Muon Source (ISIS) in Oxfordshire. They worked alongside partners at the University of Umea and European Spallation Source in Sweden.

It is the most recent in a series of research collaborations by this team, investigating the cellular proteins responsible for apoptosis.

Inside Tesla’s New $10,000 Home For Sustainable Living

Yup that’s right a Tesla Affordable Home.


Known for turning a sofa in the Boca Chica SpaceX office into his bed, Elon Musk, The World’s Richest Man, took it to another level when he announced Tesla’s $10,000 sustainable unboxable moveable home. If you are remotely familiar with the Tesla CEO, you wouldn’t be surprised that he is building a sustainable home. So, how did Elon go from overhauling the tech space to completely disrupting the real estate industry?Well, it all started with this tweet from 2020. At the height of the pandemic, Elon Musk made this insane announcement.

“Genotoxic” Warning: Chemical Found in Common Sweetener Damages DNA

Sucralose, a widely used artificial sweetener, produces a DNA

DNA, or deoxyribonucleic acid, is a molecule composed of two long strands of nucleotides that coil around each other to form a double helix. It is the hereditary material in humans and almost all other organisms that carries genetic instructions for development, functioning, growth, and reproduction. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

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