A team of astronomers has discovered a disappearing planet orbiting a star 1,000 lightyears away from our Solar System, named TOI-2535 b.
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16-h Fasting Optimizes Cancer Immunotherapy in Mice And Humans
(Cell Metabolism 38, 944–962.e1–e14; May 5, 2026)
During preparation of Data S1, leucine values were inadvertently pasted into the valine entries for Figure S2E, and the tumor weight unit for Figure 6B was labeled as mg instead of g. These errors were confined to Data S1 and did not affect the corresponding published figures or analyses. The valine entries and the tumor weight unit have been corrected.
In Figure 4M, maximal respiration values for the TCM+Ile: Bcat2Het group were inadvertently copied into the basal respiration entries and used in the corresponding plot. The original Seahorse measurements were unaffected. The basal respiration entries, plot, and associated statistical comparisons have been corrected using the original data.
Is this the reason behind hundreds of little red dots in the sky?
Now researchers from Johns Hopkins University in Baltimore think they have the answer – a never-before-seen type of black hole, according to their paper in Physical Review Letters.
‘They are very compact, red objects, seen as they were within roughly the first billion years after the Big Bang,’ the study’s co-author, Loris Del Grosso, tells Metro.
‘At first they were puzzling because they did not fit either of the obvious explanations.’
What Happens When Tau Proteins First Start Clumping Together?
Dr. Sue-Ann Mok discusses efforts to study the earliest stages of tau aggregation using single-molecule mass photometry. The work aims to identify harmful tau species and support the development of targeted diagnostics and therapies.
The structural basis of IL-36R proinflammatory signaling mediated by IL-36γ and IL-37
Structural insights reveal how IL-36R is activated by distinct cytokines and antagonized by spesolimab.
Microchimerism: A new concept
Microchimerism is the presence of cells from one individual in another genetically distinct individual. Pregnancy is the main cause of natural microchimerism through transplacental bi-directional cell trafficking between mother and fetus. In addition to a variety of cell-free substances, it is now well-recognized that some cells are also exchanged in pregnancy. Furthermore, it is now known that microchimerism persists decades later both in mother and in her progeny. The consequences of pregnancy-related microchimerism are under active investigation. However, many authors have suggested a close relationship linking fetal microchimerism and the development of autoimmune diseases. Fetal microchimerism is emerging as a potential contributing factor in certain diseases, including cancer.
Making metal–organic frameworks easier to shape for electronic devices
In 1974, the University of Melbourne’s chemistry professor Richard Robson had the idea of replacing the wooden balls and metal rods used in structural models with molecules and chemical bonds. He began experimenting with copper ions linked by a four-armed organic molecule, creating a structure with a cavity. His work laid the foundation for metal–organic frameworks (MOFs), a class of porous materials formed by linking metal ions with organic molecules. Their pores can capture pollutants, support chemical reactions and store gases, giving MOFs a wide range of potential applications.
MOFs exhibit exceptional properties arising from their porous structures that are difficult to achieve with conventional materials, enabling applications such as gas storage, separation and pollutant capture. These unique properties also make MOFs promising candidates for functional devices, such as chemical sensors and electronic devices. However, their delicate structures can be damaged during dry etching, a process that uses energetic particles, such as ion or electron beams, to remove material and create patterns.
“”Cell-based models of the human cortex transplanted into mice produce neurons that are inaccessible in vitro
And could enable scientists to link brain injury to behaviour.doi: https://doi.org/10.1038/d41586-026-02967-7
PRISM helps robots move better by learning how forces and motion interact
A new neural network component, developed at University of Michigan Engineering, challenges a common assumption in robot learning: that the same general-purpose neural networks used for image recognition are equally suited to controlling physical movement.
In image classification, a neural network maps an image to a label but does not change the image. During robotic motor control, actions—like a humanoid robot moving a limb—change the robot’s physical state, which in turn changes what sensors observe next.
Robot movement and goals involve multiplicative relationships among physical variables. For example, the forces acting on one joint depend on the positions and velocities of other joints, while quantities such as mechanical power and contact multiply forces and motion.
Shape-shifting rubber blades could make tidal power cheaper
Fitting tidal turbines with flexible rubber blades could enable the machines to generate cheaper power by making them simpler and tougher, a study published in the journal Nature suggests.
Rubber blades that change shape in strong currents can generate as much electricity as today’s most advanced designs, without the complex machinery they need to survive at sea, researchers say.
Their findings show the blades naturally bend to shed excess force, reducing by up to one-third the rapid swings in load that wear turbines out.