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Something Disturbing Happens When You Solve Einstein’s Equations This Way
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Kurt Gödel discovered a solution to General Relativity that allows time travel without any exotic physics, revealing that the theory doesn’t actually guarantee a consistent chain of cause and effect. His “Gödel universe” shows that under certain conditions, the structure of spacetime itself can loop back on itself—blurring the line between past and future and exposing a deep limitation in our understanding of reality.
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Hosted by matt o’dowd written by matt o’dowd post production by leonardo scholzer directed by andrew kornhaber associate producer: bahar gholipour executive producer: andrew kornhaber executive in charge for PBS: maribel lopez director of programming for PBS: gabrielle ewing assistant director of programming for PBS: mike martin.
The terrifying quantum entanglement theory that breaks reality
What if the most basic assumptions about reality, that objects are separate, and distance is real… are completely wrong? For centuries, classical physics described a predictable, local universe where nothing influenced anything faster than light. Then, quantum entanglement arrived, breaking our entire assumption of reality and terrifying even the most brilliant minds, including Albert Einstein.
00:00 Quantum Entanglement Theory That Breaks Reality.
01:32 The Theory of Quantum Entanglement.
10:58 The Collapse of Local Realism.
20:44 Why Reality Doesn’t Look Quantum.
23:35 The Psychological Consequence of a Nonlocal Reality.
Aperture explores the ideas shaping how we think — philosophy, psychology.
and the hidden forces behind human behavior. New perspectives, every week.
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Human DNA-PKcs promotes broken DNA-end structure independence during NHEJ
Whether DNA-PKcs is necessary for non-homologous end joining has been biochemically obscure. Through optimization of reaction conditions, Fujii and Modesti show that DNA-PKcs plays a constructive role, which leads to indistinguishable repair efficiencies between cohesive-end and blunt-end DNA substrates.
Abstract: Metabolic syndrome and excessive alcohol consumption lead to liver injury and fibrosis, characterized by increased collagen deposition from hepatic stellate cells
https://doi.org/10.1172/JCI197923 Here, David A. Brenner & team discover the RNA-binding protein LARP6 as a master coordinator of hepatic stellate cell activation and fibrosis, using human tissue and liver spheroid models of MASH and MetALD.
The image shows collagen labeling (red) in human liver spheroids MASH model with LARP6-targeting ASO (DAPI, blue). Collagen labeling is decreased compared with MASH control.
11 Center for Epigenomics, UCSD, La Jolla, California, USA.
12 Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, USA.
13 Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, Florida, USA.
