Researchers have successfully regenerated skeletal and connective tissue, although the new tissue was not perfectly formed. The result demonstrates a critical step forward in limb regeneration.
Get the latest international news and world events from around the world.
Regulatory derived TGF-β signaling governs the differentiation and maintenance of tumor-infiltrating bystander CD8+ T cells
Lin et al. reveal that tumor-infiltrating bystander CD8+ T cells are heterogeneous and undergo a TCM-to-TEM-to-TRM differentiation trajectory driven by Treg-derived TGF-β signaling through suppression of KLF2. This mechanism sustains bystander CD8+ T cell heterogeneity and accumulation in tumors and provides a targetable mechanism for cancer immunotherapy.
Scientists Changed a Lifeform’s Fundamental Code. It Shouldn’t Have Survived—but It Did
Life—at least, as we know it—needs 20 amino acids, which it combines into the proteins that build living tissues. How life actually arrived at a minimum of 20 canonical amino acids (CAAs) in its journey from primordial ooze, however, is still a mystery. Some microbial species use up to 22 amino acids, but no species on Earth uses fewer than 20.
However, that may not have always been the case. Curious about how the precursors of life may have made it on a hostile young Earth before LUCA (the Last Universal Common Ancestor of all organisms) finally came into being, a team of researchers from Columbia University set out to see whether microbes emerging back then could have possibly run on fewer than 20 amino acids.
The universe evolves like a life form
What if the laws of physics are not fixed, but constantly evolving?
Biochemist Timothy Jackson argues that contrary to our assumptions that reality is governed by fixed laws, fundamental reality is a lawless flux, a chaos of unpredictable change. What needs explaining is not chaos but the stability and order that emerge from it.
Darwin’s central insight, Jackson suggests, was to show how such order might emerge, via natural selection: a principle which can explain, but never predict, the patterns that make up the world.
Tap to read his full article.
We tend to think of reality as made up of things, governed by fixed laws that determine how they change over time. But biochemist Timothy Jackson argues that this is back to front: fundamental reality is a lawless flux, a chaos of unpredictable change, and what needs explaining is not chaos but the stability and order that emerge from it. The “laws” of physics are not eternal truths but descriptions of patterns that have persisted long enough to look permanent. Darwin’s central insight, Jackson suggests, was to show how such order might emerge, via natural selection—a principle which can explain, but never predict, the patterns that make up the world.
From physicalism to “biologism”
Telemedicine use grew without boosting medical visits or spending, analysis shows
New UCLA-led research finds that the use of telemedicine has not significantly increased visits and medical spending across all payer types. The findings, published in JAMA Network Open, could ease concerns among lawmakers that the telemedicine expansion that occurred during the COVID pandemic would result in large utilization and spending increases.
With the declaration of the COVID pandemic in 2020, the Centers for Medicare & Medicaid Services (CMS) changed key policies regarding telemedicine flexibility, such as introducing payment parity with in-person visits, waiving geographic restrictions, and eliminating out-of-pocket cost sharing.
Once the pandemic was declared over, however, lawmakers extended these changes to analyze how telemedicine impacted health care use and spending. Those CMS flexibilities are due to expire in 2027, and lawmakers continue to debate whether to permanently extend or modify them.
A new scientific discovery is challenging long-held assumptions in modern physics, suggesting that the universe may not behave strictly according to established rules
Researchers believe the findings could reshape our understanding of fundamental forces, space, and time.
#universe #cosmos #wion.
About Channel:
WION The World is One News examines global issues with in-depth analysis. We provide much more than the news of the day. Our aim is to empower people to explore their world. With our Global headquarters in New Delhi, we bring you news on the hour, by the hour. We deliver information that is not biased. We are journalists who are neutral to the core and non-partisan when it comes to world politics. People are tired of biased reportage and we stand for a globalized united world. So for us, the World is truly One.
Please keep discussions on this channel clean and respectful and refrain from using racist or sexist slurs and personal insults.
Check out our website: http://www.wionews.com
The Hammer of AI: When Every Problem Looks Like a Nail
There is no dataset for grief.
No metric for justice.
No optimizer for legitimacy.
And yet we keep bringing the Hammer of AI to every problem we face. Climate change. Pandemics. Cancer. Energy. War. Political corruption. There is no problem that the omnipresent, all-knowing, all-mighty artificial superintelligence will not eventually crack.
This is a religion. Technology is its faith. Silicon Valley is its Promised Land. Entrepreneurs are its prophets. And we are all believers.
I should know. I used to be one.
In my latest piece on Singularity Weblog, I argue that some problems do bend to computation: fusion, protein folding, the genome. But others do not. They are not computable, only livable. And when we hammer them anyway, things break. Sometimes the thing that breaks is the problem. Sometimes it is us.
AI Will Replace Most Jobs
AI is moving faster than most people realize.
In this video, Geoffrey Hinton (the “Godfather of AI”) explains why we may not be able to slow it down, what happens to jobs, and why the future could be very different from what we expect.
If this video helped you understand AI a bit better and you’d like to support the channel, I’d really appreciate it:
👉 https://www.paypal.com/ncp/payment/ML… job displacement to loss of control and growing inequality, this is a clear look at where AI is heading. — 🎥 Resources related to this topic: 🤖 AI Voice & Tools (ElevenLabs): https://try.elevenlabs.io/dw64rd295juq #ad 📚 Want to understand where AI is going? 👉 “Not Insects: The Life of Geoffrey Hinton” – Paul D. Johnson: https://amzn.to/4eYKYrm #ad — ⏱️ Video Chapters: 00:00 AI Can’t Be Slowed Down 00:40 AI and Job Loss Explained 01:45 AI Will Replace Most Jobs 03:10 AI Replaces Human Intelligence 04:05 The Control Problem 05:10 Real AI in Action (Agents) 06:10 The Future of Work 06:50 Why This Is Hard to Accept — 📚 Recommended reading on AI: 👉 “How to Create a Mind: The Secret of Human Thought Revealed” – Ray Kurzweil: https://amzn.to/3R3oMlV #ad 👉 “Scary Smart” – Mo Gawdat: https://amzn.to/4b8n9v0 #ad 👉 “Co-Intelligence” – Ethan Mollick: https://amzn.to/4bmUe57 #ad — 🧠 About this channel: Synth Insights highlights the most important ideas from leading voices in AI — breaking them down into clear, practical insights you can actually understand and use. The goal is simple: help you stay ahead of what’s coming. — (As an Amazon Associate, I earn from qualifying purchases. This description may contain affiliate links, which means I may receive a commission at no extra cost to you.) #AI #ArtificialIntelligence #GeoffreyHinton #FutureOfAI #AGI
From job displacement to loss of control and growing inequality, this is a clear look at where AI is heading.
🎥 Resources related to this topic:
🤖 AI Voice & Tools (ElevenLabs):