This study found that impaired kidney function was linked to increased plasma cerebral amyloidosis biomarkers, but ratio-based measures showed stable sensitivity and specificity for detecting cerebral amyloidosis across all eGFR groups.
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Aedes aegypti, commonly known as the yellow fever mosquito, is a highly adapted, invasive mosquito species recognized as a major global health threat that acts as the primary vector for several severe diseases, most notably dengue fever, as well as yellow fever, chikungunya and Zika virus. Local government agencies conduct routine molecular surveillance of these mosquitoes to detect and track viruses. However, they are primarily limited to using conventional reverse transcription polymerase chain reaction methodologies, which can only detect known pathogens that have already been identified and for which specific genetic primers have been developed.
Recent research efforts applying high-throughput RNA sequencing have led to a large expansion in the mosquito virome (the entire collection of viruses contained within mosquitoes). However, questions remain as to how persistent insect viruses are within mosquito colonies, how insect viruses interact with mosquito immune responses and how frequently insect viruses can be transmitted.
A new study by Boston University Chobanian & Avedisian School of Medicine researchers looked at the mosquitoes’ immune response to discover many more insect viruses and they hope to someday use the mosquitoes’ own immune system to battle some of the most pervasive and antagonistic human viruses. The findings are published in the journal Nature Communications.
Xiaochang Zhang & team introduce exon annotation for nonsense-mediated mRNA (EANMD) and report on alternatively spliced exons in the brain that trigger mRNA decay, noting modulation of such exons in disease-causal genes can potentially treat neurodevelopmental disorders.
Address correspondence to: Xiaochang Zhang, University of Chicago, Cummings Life Science Center 507A, 920 E. 58th St., Chicago, Illinois 60,637, USA. Phone: 773.834.5369; Email: [email protected].
Daniel de Florian had already established himself as a theoretical physicist—leading a group at CERN that contributed to the discovery of the Higgs boson—when he had an idea: introducing physics into high schools using virtual reality (VR). He believed that younger generations were drawn to less traditional ways of accessing science and that VR might be worth a try. As director of the Institute of Physical Sciences at the National University of General San Martín, located on the outskirts of the sprawling metropolis of Buenos Aires in Argentina, he had the resources to pursue the idea.
In 2024, de Florian began developing a combination of science, gaming, and immersive technology to create a VR-boosted version of high school physics courses. With funding from an international bank, he conducted the first pilot tests in 2025. In the VR program, students could manipulate atoms, create molecules, and solve challenges such as protecting nature on a fictional planet under various physical threats.
De Florian told Physics Magazine about his experience developing this unconventional educational tool.
Quantum computers, devices that process information leveraging quantum mechanical effects, could tackle some tasks that are difficult or impossible to solve using classical computers. These systems represent data as qubits, units of information that can exist in multiple states at once, unlike the bits used by classical computers that represent data using binary values (“0” or “1”).
Some of the quantum computers developed in recent years store quantum information in the spin (i.e., intrinsic angular momentum) of electrons or nuclei that are trapped in small semiconductor-based structures, known as quantum dots. For these devices to operate reliably, however, engineers need to be able to precisely measure the quantum states of the spin qubits they rely on, a process that is known as qubit readout. It would also be advantageous for these states to be precisely measured in a way that is architecturally compact, or in other words, using space-efficient hardware as opposed to numerous bulkier components.
Researchers at Quantum Motion and University College London (UCL) recently introduced a new approach to clearly read out the states of spin qubits leveraging high-frequency electrical signals. This method, introduced in a paper published in Nature Electronics, was developed by Jacob F. Chittock-Wood and his colleagues while he was completing his Ph.D. at UCL.
Researchers in the US and Germany have unveiled a theoretical blueprint for an atomic clock driven by a highly synchronized laser, where atoms work in concert rather than independently. Publishing their results in Physical Review Letters, Jarrod Reilly at the University of Colorado, Simon Jäger at the University of Bonn, and their colleagues in the US and Germany revived an idea first proposed in the 1990s—possibly charting a course toward the narrowest-linewidth lasers ever achieved.
In a conventional laser, a mirrored cavity bounces light back and forth between atoms, building up a bright, coherent beam. A superradiant laser works differently: rather than relying on the cavity to maintain coherence, the atoms themselves act as single coordinated emitters, collectively synchronizing their light emission.
Following early theoretical ideas emerged in the 1990s, the concept didn’t gain concrete traction until 2008, when researchers at the University of Colorado proposed that superradiant lasers could serve as a new kind of atomic clock.