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Fireworks AI discloses new breach after cloud provider hack

AI infrastructure startup Fireworks has disclosed a new security breach in which attackers accessed its development machines after breaching a third-party cloud provider.

FireWorks provides a high-performance inference platform for developers who want to deploy and run open-source artificial intelligence models (such as Mistral, Meta’s Llama, or Google’s Gemma) without worrying about hardware bottlenecks and complex infrastructure tasks.

The company notified law enforcement and customers of another security incident in early October after attackers accessed environment variables containing API keys and tokens stored as secrets for a limited number of accounts.

SEGA newsletter data breach exposes 2.2 million email addresses

Japanese gaming giant SEGA has disclosed that a data breach at its third-party newsletter provider, ARARA, exposed the email addresses of 2.2 million newsletter subscribers.

The company says the exposed data also includes 92,300 records with additional information yet to be determined. The breach affects 11 newsletters linked to SEGA and SEGA Fave products and services.

The investigation found that the compromised data did not include customer names, dates of birth, gender, addresses, phone numbers, credit card details, or account passwords.

Meteors don’t just burn up. What really happens is far more violent

Scientists have uncovered seven surprising stages that space rocks go through as they hurtle toward Earth, revealing that melting and violent fragmentation, rather than simple evaporation, determine their fate. The discovery could help explain why meteorites scatter across the ground and how dangerous asteroids explode in Earth’s atmosphere.

Scientists have gained a clearer understanding of what happens when rocks from space plunge into Earth’s atmosphere and survive the journey to the ground. After examining video recordings and photographs of 75 meteorite falls, researchers identified seven stages that describe how these objects transform into meteorites. Their analysis reveals that melting and breaking apart play a much greater role than previously believed in determining how much material a rock loses, how quickly it slows down, and where its fragments eventually land. The findings were published in the journal Meteoritics & Planetary Science.

“We used to think that solid rocks would evaporate from the enormous heat and brilliant light generated in the air collision,” said meteor astronomer and lead author Dr. Peter Jenniskens of the SETI Institute and NASA Ames Research Center. “We found instead that first melting and then fragmentation controls how a rock loses mass.”

The causes of cachexia: key signals and the brain

Cachexia is a systemic condition of progressive weight loss and muscle and adipose tissue wasting, often seen in cancer and associated with poor prognosis. This Review explores the connection between circulating signalling factors and the brain in the development of cachexia and argues for the importance of pathways within the brain as both drivers of key features of cancer cachexia and promising therapeutic targets.

Medicine Without Drugs: An Israeli Breakthrough in Nanomedicine

A research team from the Technion’s Wolfson Faculty of Chemical Engineering has developed an original technology for treating cancer using nanoparticles that carry no drugs at all, and has demonstrated its effectiveness against particularly dangerous and stubborn tumors.

Nvidia scandal may test fragile US-China truce, experts say

U.S. Commerce Dept looks to cut off China’s current ability to remotely control Nvidia chips outside China.

The geopolitical stakes around frontier AI compute just escalated significantly. 🏛️⚡️

While physical hardware embargoes (restricting shipping A100/H100/H200 accelerators to Chinese destinations) have been active under U.S. Export Administration Regulations (EAR), enforcing remote cloud access remained a major enforcement friction point.

Here is the breakdown of why this shift is happening now:

1. The Compute-as-a-Service Loophole.

Chinese AI labs and tech entities have routinely leased compute clusters housed in neutral or third-party jurisdictions (e.g., Southeast Asian cloud nodes). Because the silicon physically resides outside China, no raw hardware crosses restricted borders—yet foreign engineers execute training runs remotely.

2. Shift in Lobbying Dynamics.

Nvidia has historically pushed back against broad export bans to protect global commercial revenue and maintain market presence. However, following recent intelligence reports and congressional inquiries into data-center intermediaries (like Megaspeed), Capitol Hill’s appetite for tighter enforcement has expanded.

Retatrutide Reduces Knee Osteoarthritis Pain and Weight, Improves Physical Function

The investigational triple incretin agonist drug retatrutide was associated with significant improvement in knee osteoarthritis (OA) pain and physical function along with weight loss in people with painful knee osteoarthritis and obesity, data from two phase 3 trials showed.

“We saw very exciting amounts of pain reduction and function improvement over time. I think this is a big advance… Osteoarthritis has lacked effective therapies for so long,” study investigator Philip Conaghan, MBBS, PhD, director of the NIHR Biomedical Research Centre in Leeds and professor of musculoskeletal medicine at the University of Leeds, United Kingdom, told Medscape Medical News.

The data came from Eli Lilly’s TRIUMPH-4 trial, of once-weekly retatrutide in different doses compared with placebo for 68 weeks, and TRIUMPH-1-OA, a substudy of a larger trial investigating the triple GLP-1, GIP, and glucagon receptor agonist for treating obesity. Conaghan presented results from TRIUMPH-4 on November 8, 2026, and will present the TRIUMPH-1-OA data on November 10, 2026, both at the American College of Rheumatology (ACR) 2026 Annual Meeting in Orlando, Florida.