Aeran and colleagues present research on targeted gene therapy vector engineering and pre-clinical testing of neuron-targeted AAV9-based constructs for STXBP1-related neurodevelopmental and epileptic encephalopathies. Candidate vectors designed to target specific neuronal types and detarget tissues associated with toxicity produced robust phenotypic reversal in Stxbp1 +/− mice and were well tolerated in monkeys.
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Gödel, Escher, Bach author Doug Hofstadter on the state of AI today
Listen to the podcast episode here: https://www.buzzsprout.com/222312/131…
Life Summit — Tomorrow.bio
Many people want to live longer than what is currently possible, but medical technology is not progressing fast enough. At Tomorrow Biostasis, we use the latest cryopreservation technology to medically preserve and protect you for as long as it is needed. When medical technology has solved the life extension and aging problems, you will be reanimated to enjoy an extended life.
On the YouTube channel of Tomorrow Biostasis you can find more information about the concepts of cryopreservation, cryonics, biostasis, vitrification, human revival, and more. We also provide you with practical information about signing up with Tomorrow Biostasis. Get ready to get an insight into the fascinating world of cryopreservation!
Visit our website at: https://bit.ly/35KsOIq Sign up for Biostasis: https://bit.ly/3hGb6sq Schedule a free Consultation: https://bit.ly/3IIwkll.
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Analogy as the Core of Cognition
In this Presidential Lecture, cognitive scientist Douglas Hofstadter examines the role and contributions of analogy in cognition, using a variety of analogies to illustrate his points.
Stanford University:
Stanford Humanities Center:
Stanford University Channel on YouTube:
Gödel, Escher, Bach author Doug Hofstadter on why today’s AI terrifies him
Wonderful book.
Douglas Hofstadter, the Pulitzer Prize–winning author of Gödel, Escher, Bach, voices his concerns about how the current wave of rapid advancements in AI may endanger humanity.
CHAPTERS
0:00 Introduction.
0:34 When I started out, computers were rigid.
1:29 I thought Artificial Intelligence would take hundreds of years.
1:59 I never imagined computers would rival humans so soon.
2:53 It feels like humans are about to be eclipsed.
4:01 I feel diminished, inferior.
5:01 AI pioneer Geoff Hinton may regret part of his life’s work.
6:07 Conclusion: what do you think?
WATCH THE FULL INTERVIEW
• Gödel, Escher, Bach author Doug Hofstadter…
READ \
New technique cools high-performance chips from the inside out
Researchers at the Korea Advanced Institute of Science and Technology (KAIST) have developed a technique to carve microscopic liquid-cooling channels directly inside silicon semiconductor chips.
Interestingly, the computer architecture slashed the energy required for cooling by pumping ordinary, room-temperature water straight through the chip’s internal structure.
“As the performance of AI semiconductors and advanced electronic packaging becomes increasingly limited by heat, we expect this technology to serve as a foundational cooling solution for future high-performance computing systems,” said Professor Sung Jin Kim.
[News] World’s Smallest Semiconductor Nanotube Achieved at 1 Nanometer
A research team led by the The University of Tokyo has fabricated the world’s smallest semiconductor nanotube, according to a study published in the latest issue of Science. Using boron nitride (BN) nanotubes as a template, the researchers successfully synthesized single-walled molybdenum disulfide (MoS₂) nanotubes with a diameter of just 1 nanometer—roughly one hundred-thousandth the width of a human hair.
The achievement not only validates theoretical predictions about the electronic properties of ultrafine materials made decades ago, but also opens new possibilities for the development of next-generation miniaturized electronic devices.
Carbon nanotubes have long attracted attention for their exceptional mechanical and electrical properties. However, slight variations in their atomic structure can significantly alter their conductivity, posing challenges for transistor applications. In contrast, MoS₂ is an intrinsically semiconducting material with promising potential for semiconductor electronics, high-sensitivity sensing, and quantum-scale physics research. Yet producing ultrathin, structurally controlled MoS₂ nanotubes has remained a major challenge, as stability and fabrication complexity increase dramatically as nanotube diameters shrink.
NASA selects mission to study space weather interaction with Earth’s atmosphere
WASHINGTON — NASA has selected for development a space science mission that will study how space weather interacts with Earth’s atmosphere.
NASA announced June 18 that the Dynamic Atmosphere-Ionosphere Explorer, or DAPHNE, mission will proceed into the next phase of development, with a launch planned for no earlier than 2029.
DAPHNE was one of three concepts selected by NASA for study in 2024 for a mission concept called Dynamical Neutral Atmosphere-Ionosphere Coupling, or DYNAMIC, that was recommended by the heliophysics decadal survey in 2013 to examine the coupling between regions of the atmosphere and space weather.
Lincoln Cannon: Are Science and Religion Mutually Exclusive or Complimentary?
Are science and religion enemies or allies?
I recorded this debate 14 years ago, and the question has only gotten sharper.
Lincoln Cannon is a software engineer with degrees in philosophy and business. He is also president of the Mormon Transhumanist Association. So when he argues that science and religion are complementary, he is not speaking from ignorance of either side.
I disagree with him. I think they are mutually exclusive. He thinks they complete each other.
So we sat down and argued it out. Friendly, but real.
This was a special edition of Singularity. FM, and it remains one of the more honest conversations I have had about belief, reason, and what transhumanism owes to both. The questions we wrestled with sit right at the heart of #transhumanism and the #futureofreligion in an age of accelerating #technology.