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Human-machine learning boosts noninvasive brain-computer control in untrained users

Implantable devices in the brain have been used for about 30 years to assist people with disabilities in completing motor tasks. However, the devices are simply not accessible to the vast majority of people who need help. Despite decades of work in this field, fewer than 100 people worldwide have benefited from the technology. The costs are prohibitive, and the brain surgeries are inherently risky.

That’s why Carnegie Mellon researchers, including Bin He, professor of biomedical engineering, electrical and computer engineering, and the Neuroscience Institute, have long been working on noninvasive brain-computer interfaces (BCIs) to develop technology that is less expensive, safer and more accessible to a wider population. Over the past 10 to 15 years, they have used noninvasive BCIs to fly a drone, control a robotic arm, maintain continuous control of a robotic arm and, most recently, complete fine motor tasks at the finger level. Yet the accuracy and level of control using noninvasive technology remain challenging.

Webb telescope discovers hidden planet in famous star system

Astronomers using NASA’s James Webb Space Telescope have discovered a giant planet outside our solar system, called an exoplanet, hiding within one of the most intensely studied planetary systems in the Milky Way galaxy.

The young, nearby star Beta Pictoris was already known to host two giant planets: Beta Pictoris b, one of the first exoplanets ever directly imaged, and Beta Pictoris c. The newly identified Beta Pictoris d makes it only the second planetary system known to contain at least three imaged planets.

Unlike Beta Pictoris b and c, however, Beta Pictoris d was discovered not by identifying a bright point of light but by detecting the unique chemical fingerprint of its atmosphere, a technique that could transform the search for worlds around other stars.

Newly Discovered ‘Footprint of Death’ May Help Viruses Spread

The cell churn that goes on inside our bodies is vast, with hundreds of billions of cells dying off and being replaced every day. Keeping that constant biological overhaul running smoothly is crucial in maintaining good health.

Researchers have now identified a new ‘footprint of death’ that cells leave behind as they die to guide the immune system in its waste-removal role.

It seems this process can also be hijacked by viruses to spread themselves further.

Before babies can hear, their brains are already wiring for sound

Long before a baby’s ears are functional, the brain is already building the circuitry needed for hearing, according to new research from Johns Hopkins University. Published in the journal Science Advances, the study in mice identifies a previously unknown neural “shortcut” that organizes the auditory system before birth, offering new insight into how the auditory system prepares to process sound and eventually learn language.

While it’s well-known that sound travels from the ear to the auditory cortex, the brain’s hub for hearing, Johns Hopkins researchers discovered a new neural circuit that bypasses the ear entirely. Their findings show that the frontal cortex—the region involved in vocalization—sends signals directly to the auditory cortex, allowing the developing brain to activate hearing-related circuits before external sounds can be heard.

“Our results provide the first direct functional evidence of this biological shortcut that doesn’t go through hearing,” says senior author Patrick Kanold, a professor of biomedical engineering and neuroscience at Johns Hopkins. “It’s a novel brain activity source that can shape the earliest development in mammals, like interpreting information and discerning complex sounds.”

Breakdown of immune cells’ interaction is key driver in aging, study finds

We may age at different rates, but none of us escapes aging. A study in mice and human cells by Stanford Medicine researchers pins much of the blame on a particular type of immune cell’s increasing inability, with advancing age, to gobble up another immune cell type.

So-called tissue-resident macrophages appear to be central coordinators of age-related organ decline. Blocking a single receptor on these cells preserved the youthfulness of multiple organs in mice, including the brain, heart, skeletal and heart muscle, liver, spleen, bone marrow, kidney and colon. The receptor binds specifically to a hormone known to cause inflammation and pain in humans as well as mice.

In mice, selectively disabling this receptor exclusively on tissue-resident macrophages prevented chronic inflammation-driven disorders of aging, including frailty, excessive fat accumulation and heart trouble. It also substantially slowed cognitive decline, said Katrin Andreasson, MD, the Edward F. and Irene Thiel Pimley professor of neurology and neurological sciences.

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