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Gravitational wave signal tests Einstein’s theory of general relativity

For those who watch gravitational waves roll in from the universe, GW250114 is a big one. It’s the clearest gravitational wave signal from a binary black hole merger to date, and it gives researchers an opportunity to test Albert Einstein’s theory of gravity, known as general relativity.

“What’s fantastic is the event is pretty much identical to the first one we observed 10 years ago, GW150914. The reason it’s so much clearer is purely because our detectors have become much more accurate in the past 10 years,” said Cornell physicist Keefe Mitman, a NASA Hubble Postdoctoral Fellow at the Cornell Center for Astrophysics and Planetary Science in the College of Arts and Sciences.

Mitman is a co-author of the paper analyzing the wave, “Black Hole Spectroscopy and Tests of General Relativity with GW250114,” published in Physical Review Letters. It was written by the LIGO Scientific Collaboration, the Virgo Collaboration in Italy and the KAGRA Collaboration in Japan. Cornell researchers have been leading contributors to the LIGO-VIRGO-KAGRA project since its beginning in the early 1990s.

Bacteria Communicate Using Techniques Similar to Radio

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Hello and welcome! My name is Anton and in this video, we will talk about a strange bacterial communication technique similar to radio waves.
Links:
https://www.cell.com/current-biology/fulltext/S0960-9822…all%3Dtrue.
Previous videos: https://www.youtube.com/watch?v=4M872c27bSc.

https://www.science.org/doi/10.1126/sciadv.adj1539

#science #radio #bacteria.

0:00 Bacterial communication and social lives.
1:20 Quorum sensing and multilingual bacteria?
4:20 Physical bridge communication.
5:20 New communication involves radio like processing.
8:00 What this is used for.
9:15 Why this is important for the medical fields.

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Juno spacecraft reveals thickness of Europa’s ice shell

“The 18-mile estimate relates to the cold, rigid, conductive outer layer of a pure water ice shell,” said Dr. Steve Levin. [ https://www.labroots.com/trending/space/30133/juno-spacecraf…ce-shell-2](https://www.labroots.com/trending/space/30133/juno-spacecraf…ce-shell-2)


How thick is the ice shell on Jupiter’s moon, Europa? This is what a recent study published in Nature Astronomy hopes to address as a team of scientists revealed groundbreaking insights into Europa’s ice shell thickness and subsurface structure. This study has the potential to help scientists better understand the interior composition of Europa and whether it could support life as we know it.

For the study, the researchers analyzed data obtained by NASA’s Juno spacecraft in 2022 when the spacecraft came within 220 miles (360 kilometers) of Europa’s surface. The goal of the study was to put constraints on the thickness of Europa’s ice shell, with the researchers noting current estimates range from 1.86 miles (3 kilometers) to more than 18.6 miles (30 kilometers). Since Europa is a prime target for the search for life beyond Earth, scientists hypothesize that cracks exist within the ice shell, enabling the delivery of nutrients from the surface to the subsurface liquid water ocean. In the end, the researchers estimated the average thickness of Europa’s ice shell is approximately 18 miles (29 kilometers).

Researchers Show AI Robots Vulnerable to Text Attacks

“I expect vision-language models to play a major role in future embodied AI systems,” said Dr. Alvaro Cardenas.


How can misleading texts negatively affect AI behavior? This is what a recently submitted study hopes to address as a team of researchers from the University of California, Santa Cruz and Johns Hopkins University investigated the potential security risks of embodied AI, which is AI fixed in a physical body that uses observations to adapt to its environment, as opposed to using text and data, and include cars and robots. This study has the potential to help scientists, engineers, and the public better understand the risks for AI and the steps to take to mitigate them.

For the study, the researchers introduced CHAI (Command Hijacking against embodied AI), which is designed to combat outside threats to embodied AI systems, including misleading text and imagery. Instead, CHAI employs counterattacks that embodied Ais can use to disseminate right from wrong regarding text and images. The researchers tested CHAI on a variety of AI-based systems, including drone emergency landing, autonomous driving, aerial object tracking, and robotic vehicles. In the end, the researchers discovered that CHAI successfully identified incoming attacks while emphasizing the need for enhancing security measures for embodied AI.

Cell Signaling and Communication between Cells

Cell signaling is how cells communicate through reception, transduction, and response, using chemical ligands that bind to specific receptors to transmit messages.

Communication can happen through direct contact (like gap junctions), paracrine signaling (short distances), endocrine signaling (long distances via the bloodstream), or autocrine signaling (the cell signals itself).

This process is crucial for coordinating cell functions and maintaining homeostasis in multicellular organisms.

A ribosome-bound pseudoknot in the HCV coding region stimulates viral growth by tuning viral translation

Given that pk1 is located within the HCV coding region, we next investigated a potential role in translation elongation. We inserted pk1 into the ORF of Gaussia luciferase and used the HCV IRES to initiate translation (Figure 3 B, left). To ensure that the highly structured HCV IRES did not affect pk1 folding, we included a 99-nt linker sequence with low structural propensity between the HCV IRES and pk1. As controls, we used the pk1-unzip mutant and a randomized pk1, where the pk1 sequence was shuffled by three nucleotides, thereby maintaining the same amino acid composition as the WT pk1.

The RNA constructs described above were transfected into cells, and luciferase activity was measured at various time points to assess translation activity (Figure 3B, right). We observed that pk1 significantly inhibited translation elongation at all time points tested compared to the pk1-unzip and random controls. Notably, at 4 h post-transfection, there was nearly a 4-fold difference between the activity of pk1 and the pk1-unzip mutant, indicating that the pseudoknot structure itself, rather than just its constituent stems, is crucial for the observed translation inhibition (Figure 3B). To further examine the structural basis of this effect, we introduced a pk1-compensatory mutant that restores the disrupted base pairing in the pk1-unzip mutant using synonymous G-U wobble and A-U base pairs (sequence shown in Figure 3A).

Meteorin-like is associated with poor outcome in invasive candidiasis in mouse models and in humans

Studying mice and two clinical cohorts, researchers in Science TranslationalMedicine show that the protein meteorin-like worsens outcomes during invasive candidiasis by suppressing antifungal macrophages, suggesting the protein could offer a marker and potential target.

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METRNL is elevated in candidemia in mice and humans and provides a potential therapeutic target for life-threatening candidemia.

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