A drug that kills cancer cells by puncturing them comes with an additional benefit: tests in mice suggest it reduces the growth of pain-sensing nerves around tumours
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Carotid Artery Stenosis—Impactful Bias in Ischemic Stroke Classification
💬 Editorial: Stroke risk classification that relies solely on carotid stenosis severity overlooks patients with nonobstructive but high-risk carotid plaques, underestimating the true contribution of carotid disease to ischemic stroke.
Recent European Society of Cardiology guidelines and Carotid Plaque–RADS offer improved risk stratification by accounting for plaque features, with evidence showing significant gains in predictive accuracy.
This Viewpoint argues that risk classification in ischemic stroke should be expanded beyond stenosis severity to encompass other complementary features, such as plaque morphology, composition, and inflammation.
Stress-reduction molecule has potential to treat aging and metabolic disorders
University of Queensland researchers say the discovery of a new stress reduction role for a naturally occurring molecule in the body could lead to new drugs and treatment for metabolic disorders and aging.
Professor Steven Zuryn, a molecular geneticist from UQ’s Queensland Brain Institute, was part of a team that found that very small RNA molecules, called microRNAs, bind to genes and prevent them from being over-activated.
MicroRNAs were discovered in C. elegans about 30 years ago and have since been shown to be important in human health and disease. This initial discovery led to the 2024 Nobel Prize in Physiology or Medicine.
Hot, Black Ice Might Be Responsible For Neptune’s Wild Magnetism
Inside the cores of ice giant planets, the pressure and temperature are so extreme that the water residing there transitions into a phase completely unfamiliar under natural conditions on Earth.
Known as ‘superionic water’, this form of water is a type of ice. However, unlike regular ice, it’s actually hot, and also black.
For decades, scientists thought that the superionic water in the core of Neptune and Uranus was responsible for the wild, unaligned magnetic fields that the Voyager 2 spacecraft saw when passing them.
Visceral Fat Removal Extends Lifespan: Who Has The Lowest?
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Human-Centric Intelligence: A New Paradigm For AI Decision Making
In my latest Forbes article, I explore one of the most critical questions facing leaders today:
How do we use AI to augment human intelligence rather than diminish it?
AI’s true power isn’t about automation alone—it’s about amplifying human judgment, creativity, and decision-making.
#AI #HumanCentricAI #artificialintelligence #tech #AugmentedIntelligence #Forbes #Leadership #Cybersecurity #EmergingTechnology #DigitalTransformation
Human-centric AI is the new frontier; it is not AI against human intelligence, but AI with human intelligence.
Exploring the neural mechanisms that enable conscious experience
Recently, there has been convergence of thought by researchers in the fields of memory, perception, and neurology that the same neural circuitry that produces conscious memory of the past not only produces predictions of the future, but also conscious perception of the present.
In a new perspective in the Journal of Cognitive Neuroscience, researchers explain that although our conscious perception appears to simply mirror the external world, due to neural processing delays this intuitive feeling must be wrong. Instead, unconscious perceptual mechanisms represent a timeline that is then consciously remembered. Because the default mode network, along with the frontoparietal control and salience networks, are critical for simulation and memory, they are also critical for consciousness.
“The same simulation processes are used whether we are consciously remembering the past, experiencing the present or imagining the future. Perceptual mechanisms represent an ongoing, editable, ‘best estimate’ of our past, present, and future. There is no hard boundary between conscious perception and memory at milliseconds to seconds timescales,” explains corresponding author Andrew Budson, MD, professor of neurology at Boston University Chobanian & Avedisian School of Medicine.
