Engineering the age(ing) of tissues in vitro could lead to more representative and predictive models for the ageing population. This forum introduces methodological approaches for ‘age engineering’ (‘ageneering’) and further discusses future applications of age-matched cells, matrices, and microtissues in predictive disease modelling, biomarker discovery, and age-specific pharmacotoxicology.
What neuroscience reveals about how intelligence actually works — and how those insights are informing the next generation of AI architectures.
Alexander Wissner-Gross, David Rock, Simran Chana, Manolis Kellis.
✌️ Subscribe! http://bit.ly/ImaginationInAction-You… info: https://www.imaginationinaction.co/ 🐦 Join the conversation! #ImaginationInAction ====== Leading in an Intelligent World On April 10th, 225 speakers across 6 stages joined Imagination in Action at MIT Media Lab to explore how intelligence is built, deployed, governed, and directed toward the world’s hardest problems — alongside 60 startup pitches and 2 AI agent workshops with 500 participants. ======
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Leading in an Intelligent World.
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MIRA, an autonomous AI agent tested in a sandboxed electronic health record, diagnosed 574 real emergency department cases with 88.9% accuracy and outperformed physicians in a matched 311-case comparison. The system ordered tests, generated medication plans, and made admission decisions in simulation, but the authors stress that prospective validation, governance, and physician oversight are still essential.
For some time, researchers have used optical tweezers to manipulate tiny objects with incredible precision, using carefully controlled beams of laser light. So far, however, this technique has always come with strict limits on how much force it can exert.
Through new research published in Nature, a team led by Dong Wu at Anhui University, China, has unveiled an improved design: a miniature mechanical gripper controlled by light signals through an optical fiber.
Combining the precision of light-based tools with the gripping strength of mechanical devices, the device could make it far easier for researchers to manipulate and assemble objects at the microscale.
Luo et al. characterize a comprehensive molecular portrait of neurotransmitter receptor genes across 33 cancer types using multidimensional omics data from The Cancer Genome Atlas and other independent cohorts. They identify clinically relevant neuroregulatory subtypes with distinct molecular features, advancing the emerging field of cancer neuroscience.
“Don’t Wait For The Singularity.”
That was Tracy R. Atkins’ message when I sat down with him 14 years ago, and it lands harder now than it did then.
While almost every story about #ArtificialIntelligence was busy imagining the apocalypse, Tracy wrote a novel that flatly refused to. Aeternum Ray is unapologetically utopian: a series of letters from a 240-year-old father to his newborn son, looking back across centuries of love, loss, and a world watched over by an AI named Ray.
In our conversation, we get into what the #Singularity actually means to him, why he chose to write utopia when dystopia sells, whether humanity’s future is digital or whether biology still matters, and the uncomfortable question of whether we even survive the road to get there.
Fourteen years on, the technology has caught up to much of what we talked about. The harder question is whether our reasons for building it have, and that is the part I keep coming back to.
So is openly imagining a good future naive, or is it the most radical thing a #futurist can do? Watch the interview and decide for yourself.