Blog – Page 10

Somewhere in the body of a patient, a small clump of cells, growing undetected, has begun to form a tumor. It has yet to cause pain or visible symptoms of illness. Several months from now, or perhaps years, those first signs will prompt a doctor’s inquiry, a referral to a specialist, and an eventual diagnosis. Treatment will depend on how long the cancer has gone unnoticed and how far it has spread.

There were early signs, though not ones the patient or doctor could have noticed. Small fragments of RNA, cast off from dying cells or spit out of the tumor’s twisted transcriptions, floating about in the bloodstream—early signals of a tissue in distress.

A new method developed by Stanford researchers aims to bring the moment of detection much closer to the beginning. They have developed a blood-based method called RARE-seq that detects tumor-derived cell-free RNA with around 50 times the sensitivity of standard sequencing techniques.

We are urgently working to find new treatments and cures for ALS and are currently funding over 168 research projects in 12 countries. We work with many pharmaceutical companies that have attempted to bring new treatments to market.