The ability to study human neurological systems depends on having viable, accurate models of brain function. St. Jude researchers have now created a model for such research by combining thalamic cells and cortical cells derived from human induced pluripotent stem cells.

The thalamocortical system mediates multiple sensory and cognitive processes, such as perception, learning and memory. The researchers developed a model of a primitive human thalamocortical system by maintaining thalamic and cortical cell masses known as organoids in close proximity in a culture dish.

In this model, the neurons in both organoids develop and grow long-ranging processes (axons) that extend to the opposite organoid and form functional connections (synapses). The researchers determined that when these synapses are stimulated, they undergo long-term strengthening and weakening of their electrical signals, which is the hallmark of synaptic plasticity, a process that underlies certain forms of learning and memory.

Mindfulness training may cause altered states of consciousness, including disembodiment and unity, according to a University of Cambridge study. While often positive, these experiences can sometimes be unsettling. Awareness and open communication about these potential side effects are essential for both teachers and students.

A new study from the University of Cambridge suggests that participants in mindfulness training may undergo altered states of consciousness, experiencing sensations of disembodiment and unity.

The team says that while these experiences can be very positive, that is not always the case. Mindfulness teachers and students need to be aware that they can be a side-effect of training, and students should feel empowered to share their experiences with their teacher or doctor if they have any concerns.

From the article:

Ceyda Sayali, a cognitive neuroscientist at the Center for Psychedelic and Consciousness Research at Johns Hopkins University who was not involved with the study, said she was struck by the images that showed a marked change when participants on psilocybin were asked to answer…

A small new study shows reactions in the brain in people who were given psilocybin in a controlled setting.