Lifeboat Foundation

Lifespan.io is hosting its third annual conference on aging and rejuvenation biotechnology.

The Life Extension Advocacy Foundation/Lifespan.io, a nonprofit company promoting aging research, is hosting its third annual Ending Age-Related Diseases: Investment Prospects and Advances in Research conference on August 20–21 at the Stern Auditorium of the Icahn School of Medicine at Mount Sinai (New York City, USA).

The goal of this conference is to promote scientific and public discussion in order to foster the development of interventions that target aging and are capable of relieving our aging society from the burden of age-related diseases. Key topics of the conference include biomarkers of aging, discoveries in fundamental research, the development of interventions targeting the root mechanisms of aging, investment strategies, and regulatory issues that are relevant to rejuvenation research.

James W. Clement is a longevity researcher who was the 12th person on the planet to have his DNA sequenced. In 2010 James launched his Supercentenarian Research Study, which he started in 2010 with Professor George M. Church of Harvard Medical School. Since then Clement has read 20,000 medical research papers on longevity and has acquired one of the largest DNA databases of supercentenarians, the youngest of whom is 106 years old. Most recently James W. Clement is the author of the Switch: Ignite your metabolism with intermittent fasting, protein cycling, and keto. Finally, I know James personally and have gone to visit his previous research lab in Apple Valley, California, so I can honestly say that he is among the most humble humans and the hardest-working longevity researchers that I have ever seen. I have learned a lot from Clement and I hope you do too.

During this 2 hour interview with James W. Clement, we cover a variety of interesting topics such as: Clement’s journey from being a lawyer to becoming a full-time longevity researcher; the name and story behind Better Humans; why James is a transhumanist; why we have to first make it to 100 before we start taking “magic pills”; the switch between mTOR and autophagy; the importance of intermittent fasting, its time and duration; the connection between gut bacteria and dopamine; why the biggest problem of our diet is the overconsumption of both dairy and meat; protein cycling and why we can’t sustain autophagy indefinitely; the dangers of coconut oil; why all centenarian blue zones in the world eat high-carb diets and why we should try keto.

My favorite quote that I will take away from this interview with James W. Clement is:

PepsiCo’s Senior VP of R&D, Dr. Ellen de Brabander, joins me on this ideaXme (http://radioideaxme.com/) episode to talk about running the R&D engine for a $200 billion company, the parallels between pharma and food in terms of increasing customization / personalization, and her future visions for the $8 trillion global food and beverage space — (Personal caveat — While I avoid processed foods, one cannot ignore the place at the table that “big food” will have in crafting and investing in the future of health, wellness, and longevity) — https://www.youtube.com/watch?v=tDSiVlKNnRA&t=1 #Ideaxme #Pepsi #Nutrition #Research #Science #Health #Wellness #Sustainablity #Longevity #FritoLay #Tropicana #QuakerOats #Gatorade #Aquafina #MountainDew #Doritos #Cheetos #Ruffles #Tostitos #Fritos #Biotech #LifeExtension #Aging #IraPastor #Bioquark #Regenerage

Ira Pastor, ideaXme exponential health ambassador, interviews Dr. Ellen de Brabander, Senior Vice President Research and Development at PepsiCo.

Continue reading “PepsiCo: The Future Of Food” »

Dr. Theodore Ho talks about the rapidly expanding possibilities of stem cells to be used in reversing or slowing the aging process. He discusses his previous and current work with the brain, including such methods as tissue clearing, multifiber photometry and optogenetics, and single resolution calcium imaging and control. Dr. Ho is a neuroscientist and stem cell biologist studying the mechanisms and causes of biological aging and potential strategies to slow or reverse them, in order to prevent the onset of age

Associated diseases to help us live healthier and longer lives.

Continue reading “Aging and Stem Cells | Theodore Ho | TEDxMiddlebury” »

[Frame — 00:55] Liz Parrish – Introduction.

[Frame — 06:10] Gene therapy & deliver mechanisms — AAV2.

Continue reading “Liz Parrish — Gene Therapy for Healthy Longevity — Part 1” »

Acarbose and Metformin are commonly used to treat type 2 diabetes, but now they are also being tested for anti-aging effects, and according to the researchers these two FDA approved drugs have big promise.

In mice testing Acarbose and Metformin were demonstrated to increase health, lifespan, and longevity of the animals. These two drugs are now being tested in monkeys that have a similar physiology, reproductive system, and aging pattern as humans, in research being conducted at Texas Biomedical Research Institute which is supported by a pilot grant provided by the San Antonio Claude D. Pepper Older Americans Independence Center.

“I think this type of research can change what life is like for geriatric people,” said Corinna Ross, Ph.D, Associate Professor, Southwest National Primate Research Center at Texas BioMed.

Lifespan.io

 A new study published in mSystems, a journal from the American Society for Microbiology, shows that the skin and mouth microbiomes are better predictors of age than the gut microbiome.

A very broad study

Continue reading “Skin and Mouth Biomarkers More Predictive Than Gut” »

Wall Street’s Biotech Investment Wizard — On this most recent ideaXme (http://radioideaxme.com/) episode, I was honored to be joined by my friend, and biotech / pharma / healthcare investment banker extraordinaire, Frederick Frank, to talk about his 50-year career history behind the industry’s mega-deals — #Ideaxme #Biopharma #Biotech #WallStreet #Mergers #Acquisitions #VentureCapital #Genentech #Roche #BristolMyersSquibb #PrivateEquity #Health #Wellness #Longevity #Regeneration #LifeExtension #Aging #IraPastor #Bioquark #Regenerage

Ira Pastor, ideaXme exponential health ambassador, interviews Fred Frank, Founder and Chair of Evolution Life Science Partners, an investment bank focused on the needs of life sciences and healthcare companies.

Continue reading “Biotech’s Wizard Of Wall Street : Fred Frank At The Forefront of Investment” »

Lifespan.io

On this informative episode of X10, Giuliano explains proteins and how they misfold, causing the hallmark of aging known as loss of proteostasis- which leads to Alzheimer’s disease and other dangerous diseases.