The basics for tracking include blood biomarkers that have been studied for 50 – 100+ years, depending on the biomarker. Most of these biomarkers are commonly measured at a yearly physical, and are relatively cheap (35 $USD for the standard chemistry panel and complete blood count).
Category: life extension – Page 263
Nano-engineered sealer leads to more durable concrete
A nanomaterials-engineered penetrating sealer developed by Washington State University researchers is able to better protect concrete from moisture and salt—the two most damaging factors in crumbling concrete infrastructure in northern states.
The novel sealer showed a 75% improvement in repelling water and a 44% improvement in reducing salt damage in laboratory studies compared to a commercial sealer. The work could provide an additional way to address the challenge of aging bridges and pavements in the U.S.
“We focused on one of the main culprits that compromises the integrity and durability of concrete, which is moisture,” said Xianming Shi, professor in the Department of Civil and Environmental Engineering who led the work. “If you can keep concrete dry, the vast majority of durability problems would go away.”
Some People think Life Extension is “Just a Fear of Death”
Sometimes those working in the field of rejuvenation biotechnology face the accusation that what they are doing is just a fear of death, like not being scared of age-related diseases is somehow brave.
War used to be fashionable but now it isn’t
These days, war is not really portrayed in a very good light. When we think about war, we think about genocide, mass murder, and slaughter, and we call for an end to it. The popular sentiment is that war is bad and we should just do away with it.
The Dog Aging Project Will Study Longevity in 60,000 Pups
Our furry friends are about to fetch new answers to the tough problem of longevity.
The Dog Aging Project (DAP), launched in 2018, is recruiting tens of thousands of loyal canine companions for a comprehensive study. The open-sourced collaborative project, expected to last ten years, has ambitious goals: tackle the thorny problem of what contributes to aging, and test ways to prolong healthy longevity.
Aside from its massive scale—it’s the largest data-gathering program of its kind—the project stands out in that it eschews the usual method of using lab animals, grown in carefully-controlled environments and often inbred. Instead, DAP is recruiting dogs from across the country, with a smorgasbord of breeds, ages, and environments.
(Part II) Supercentenarian (112 — 116y) Blood Test Analysis
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https://www.patreon.com/MichaelLustgartenPhD
Papers referenced in the video:
Main study:
Clinical course of the longest-lived man in the world: A case report.
https://pubmed.ncbi.nlm.nih.gov/34973348/
Commonly used clinical chemistry tests as mortality predictors: Results from two large cohort studies.
https://pubmed.ncbi.nlm.nih.gov/33152050/
Predicting age by mining electronic medical records with deep learning characterizes differences between chronological and physiological age.
https://pubmed.ncbi.nlm.nih.gov/29113935/
The gamma gap predicts 4-year all-cause mortality among nonagenarians and centenarians.
https://pubmed.ncbi.nlm.nih.gov/29348636/
Implication of liver enzymes on incident cardiovascular diseases and mortality: A nationwide population-based cohort study.
Longevity Molecules and Supplements | Longevity Lifestyle Series P4 | Serena Poon Dr. David Sinclair
Do you have a longevity supplement stack? I do not at this time but this might help you. Interesting that Sinclair takes C60 but I heard that was not good for you. This video is annotated with many chapters.
In Part Four of our Instagram LIVE super series, @David Sinclair & I chat about molecules and supplements for longevity! Our hope is that you come away from this conversation with tangible tips and an understanding of how these types of supplements can maximize longevity.
In Dr. David Sinclair’s fourth Lifespan Podcast episode, he narrows in on drugs and supplements that have been reported to combat aspects of aging…sharing the latest experimental and clinical data for NAD boosters, resveratrol, fisetin, quercetin, rapamycin, spermidine, metformin, and berberine. Given the interest, a special focus is placed on the NAD precursors nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN).
…So how do these interventions influence aging at the molecular and physiological levels?
IN THIS IG LIVE REPLAY WE COVER:
Vitalik Buterin on Ethereum and immortality
In this episode of UpOnly, the creator of Ethereum Vitalik Buterin talks origin stories, his motivation, the future of Ethereum, and even biological sciences.
Presented by FTX: https://uponyl.tv/ftx.
Full show notes: https://uponly.tv/vitalik-buterin-on-ethereum-and-immortality/
Timestamps.
0:00 — Intro.
1:30 — What does Vitalik do outside of crypto? / The Invention of Language.
5:50 — What did Vitalik imagine himself doing before crypto?
8:57 — OG Canadian Crypto Scene / What do you wish you had done differently?
13:30 — Future Plans Outside of Ethereum.
15:30 — Family and Crypto.
16:50 — Ethereum Alternatives.
20:35 — Proof of Stake / NFTs.
28:15 — Where The Future is Going / Crypto Beyond Financialization.
32:25 — Ethereum Sharding / zk-STARK / MEV
36:10 — User Experience Hurdles / Multisig / Reducing Risk.
41:37 — Who is Satoshi Nakamoto?
43:35 — Donating SHIBA to Charity.
46:25 — Best Vitalik Memes.
50:06 — Multi-Chain Future vs. a Cross-Chain Future / Layer 2 / Systemic Risk.
58:30 — Layer 2 Decentralization.
1:00:05 — Implications of zkEVM
1:04:03 — Archivability of Blockchains.
1:07:14 — Security and Risks / Simplicity of Code / Web Standards.
1:12:25 — Privacy.
1:14:42 — Anti-Aging / Immortality / Adopting New Technology.
1:29:17 — Multi-planetary World / Antarctica / Cultural Shifts.
1:35:40 — Important Social Trends.
1:38:30 — Alpha