Here’s a new story on my AI & ChatGPT ideas from Singularity Group (Singularity University). Special thanks Steven Parton & Valeria Graziani:
In episode 90 of the Feedback Loop Podcast: “The Current State of Transhumanism,” we catch up with one of our first guests on the show, çΩΩ≈ΩΩ
The swift progress in biotechnology, artificial intelligence (AI), and neuroscience has been a significant contributor to the growth of transhumanism. Nevertheless, despite the increasing interest in this field, many remain apprehensive about the consequences of employing technology to augment the human body and mind. Ongoing discussions revolve around the ethics of creating superhumans, the possible hazards of artificial intelligence, and the potential societal impact of these technologies.
So according to Zoltan Istavan what’s changed and what is waiting for us in the future?
“People on metformin have 30% lower rates of almost every kind of cancer. It delays cognitive decline. Even people with diabetes who are obese and have more disease to start with but are on metformin have lower mortality rates than people without diabetes who aren’t on the drug.”
What he says is born out in numerous studies. Overall, this safe, super-cheap, decades-old drug not only treats diabetes, but it also seems to delay and compress the years of chronic illness associated with the final stage of life and extend what geroscientists call the “healthspan.”
Metformin is just one of many medications, including other old ones and some brand new inventions, that academic researchers and biotech startups are exploring to slow, stop, or perhaps even reverse aging.
For the first time, a researcher at the University of Delaware College of Health Sciences in collaboration with a team at the National Institute on Aging, a division of the National Institutes of Health, has determined that the naturally occurring dietary supplement known as nicotinamide riboside (NR) can enter the brain.
The discovery was made by Christopher Martens, assistant professor of kinesiology and applied physiology and director of the Delaware Center for Cognitive Aging Research, and Dr. Dimitrios Kapogiannis, a senior investigator at the National Institute on Aging. The finding is significant because it supports the idea that NR, upon reaching the brain, can alter the metabolism of relevant biological pathways involved in neurodegenerative diseases like Alzheimer’s. Their work was recently published in the journal Aging Cell.
Upon consumption, NR is readily converted into nicotinamide adenine dinucleotide (NAD+), which is critical to cellular repair and the repair of damaged DNA.
José Cordeiro is convinced that victory over death is only a matter of time. He believes people will soon be able to choose the age at which they want to live.
José Cordeiro, living forever has been a dream of human beings since their beginning. Currently, we live for around 100 years, whales and turtles live even longer. Is that fair?
Two U.S. congressmen have announced the formation of a bipartisan Congressional Caucus for Longevity Science.
Jeanne Calment is the world’s oldest person on record, and she lived to age 122. Here’s what a longevity expert says about why she was able to live so long.
Glioblastomas are the most common malignant tumors of the adult brain. They resist conventional treatment, including surgery, followed by radiation therapy and chemotherapy. Despite this armamentarium, glioblastomas inexorably recur.
In a new study published in Nature Communications, Isabelle Le Roux (CNRS) and her colleagues from the “Genetics and development of brain tumors” team at Paris Brain Institute have shown that the elimination of senescent cells, i.e., cells that have stopped dividing, can modify the tumor ecosystem and slow its progression. These results open up new avenues for treatment.
Glioblastoma, the most common adult brain cancer, affects 2 to 5 in 100,000 individuals. While the incidence of the disease is highest in those between 55 and 85 years old, it is increasing in all age groups. This effect can’t be attributed to improved diagnostic techniques alone, suggesting the influence of environmental factors hitherto unidentified.