Lifeboat Foundation: Safeguarding Humanity
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Category: health – Page 9

Quantum optics may turn this rare visual phenomenon into an eye test

Modern life depends on quantum physics. It makes technologies such as GPS navigation, MRI scanners and computer chips possible. Now, the same science may also lead to a new way to test the health of our eyes. A University at Buffalo-led team has used a technique from quantum optics to make a little-known visual pattern produced inside the eye easier to see—potentially opening the door to a new way to test retinal health.

Known as Boehm’s brushes, these faint, two-lobed, bowtie-shaped patterns sometimes appear in peripheral vision when polarized light scatters off structures in the retina. Because people with retinal disease may be less likely to perceive them, scientists have long wondered whether they could serve as a biomarker of retinal health.

However, Boehm’s brushes are often too hard to see, even for people with healthy eyes, to be useful in clinical practice.

The silent hormone: How adrenal tumors quietly raise cardiovascular risk over time

A major new study, published in The Lancet Diabetes & Endocrinology, has shown that cortisol levels in patients with adrenal tumors are far less stable than previously assumed. The study also found that those in whom cortisol remains persistently elevated carry a significantly greater risk of worsening high blood pressure and a heavier overall cardiometabolic burden.

Cortisol, often referred to as the “stress hormone,” is a steroid hormone produced by the adrenal glands that acts as a master regulator of metabolism, blood pressure and immune function. When benign tumors form on the adrenal glands (found incidentally in 3%–7% of adults), they can cause the body to produce cortisol independently of normal regulatory controls, a condition known as mild autonomous cortisol secretion (MACS).

Until now, it was unclear how cortisol levels in these patients change over time, and what that means for their long-term health.

Imagination is not escapism, it brings us closer to reality

Einstein called imagination “more important than knowledge,” yet we increasingly treat it as a childhood pastime we outgrow. Philosopher of mind Amy Kind argues that it’s something far more practical: the skill we draw on to make our hardest decisions, read the people around us, and work out who we want to become. Like any skill, it weakens without use — and we’re using it less. Reading for pleasure has nearly halved in two decades, fewer parents play with their children each day, and we increasingly hand our creative work to machines. If we don’t make time to exercise it, we’ll lose the capacity to conceive of things being other than they are, and risk being trapped in the present, unable to imagine a different future, let alone build one.

In recent years, amidst the hustle and bustle of contemporary life, people are devoting considerably less time to imaginative activities. Significantly fewer people are reading for pleasure today compared to 20 years ago, and in just the last decade, significantly fewer parents are making time to play with their children on a daily basis than used to be the case.

This neglect of imagination has been accelerated by the increasing reliance on generative AI tools in both personal contexts and professional contexts. In one recent survey, more than 50% of adults reported interacting with AI tool at least several times a week for personal purposes, often for learning, entertainment, or supporting their children’s education. In another study on business uses of AI, more than half of firms surveyed reported using AI in the creation of new products and services and, more generally, in their at innovation projects. With each passing day, we seem to be increasingly more willing—and perhaps even eager—to outsource our creative and imaginative efforts to machines.

Scientists unlock gut-healing power of fruits and nuts paired with the right gut microbes

University of Louisville researchers have discovered how a naturally occurring microbial compound may help protect the gut and support future treatment strategies for inflammatory bowel disease (IBD).

IBD, which includes conditions such as Crohn’s disease and ulcerative colitis, affects millions of people worldwide. The disease is characterized by chronic inflammation and damage to the intestinal lining. A healthy gut barrier helps keep harmful bacteria from leaking out of the intestines while allowing nutrients to enter the body. In people with IBD, that barrier becomes weakened, leading to inflammation, pain and long-term complications.

A research team led by Venkatakrishna Rao Jala, associate professor in the Department of Microbiology and Immunology and UofL’s Brown Cancer Center, discovered how a naturally occurring microbial metabolite called urolithin A, or UroA, which is generated by gut bacteria after digestion of foods such as pomegranates, walnuts and berries, activates a protective pathway in the intestine that may help preserve gut health.

A New Way To See Life’s Hidden Chemistry: $10 Spectrometer Could Turn Wearables Into Personal Health Labs

Researchers have developed a compact, low-cost convolutional spectrometer that delivers lab-grade precision for applications ranging from industrial quality control to non-invasive health monitoring.

Video games might modestly sharpen your memory and other cognitive skills, review suggests

Because video games are a regular part of many people’s everyday lives, researchers have spent a lot of time trying to determine whether they are beneficial or detrimental to brain health. A new study, published in Acta Psychologica, has compiled 20 years of research on how video games affect cognitive abilities into a single systematic review and meta-analysis. This comprehensive study indicates that video games may provide some helpful cognitive benefits to gamers.

On the face of it, it might seem like video games fall into the “brain rot” category of entertainment, similar to endless social media scrolling or watching television. Yet most gamers would agree that video games involve at least some degree of skill, and many researchers would agree, too.

In fact, the interactive nature of video games has positioned them as a potential tool for cognitive training, helping to exercise core mental skills like memory, attention, self-control, spatial reasoning and broader problem-solving.

STEREOseq identifies HS tunnels bearing a mucosal epithelia phenotype

1 Center for Cutaneous Biology and Immunology Research, Department of Dermatology, Henry Ford Health, Detroit, Michigan, USA.

2Department of Plastic Surgery, Henry Ford Health, Detroit, Michigan, USA.

3Center for Bioinformatics, Department of Public Health Sciences, Henry Ford Health, Detroit, Michigan, USA.

Invisible threads: How our environment quietly shapes disease

From the air we breathe to the food we eat, we are constantly exposed to thousands of chemicals—yet how these exposures affect our health has remained surprisingly difficult to understand. A new study led by researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and the Ludwig Boltzmann Institute for Network Medicine at the University of Vienna, published in Nature Communications, offers a unifying view: Diverse substances can disrupt the same biological systems and thereby contribute to disease risk in predictable ways.

Environmental pollution is estimated to contribute to around one in six deaths worldwide, but scientists have long struggled to connect specific exposures to specific diseases. One reason is the sheer complexity of the “exposome” —the totality of all environmental influences a person encounters over a lifetime. Traditionally, chemicals have been grouped by their structure or origin, but this says little about what they actually do inside the body. Two nearly identical molecules can have completely different effects, while entirely unrelated substances may trigger the same illness. This has made it difficult to move from observation to understanding.

A new study, led by Jörg Menche, CeMM adjunct PI and director of the Ludwig Boltzmann Institute for Network Medicine, and first authored by former Ph.D. student at CeMM and LBI NetMed (now a postdoc at Harvard Medical School) Salvo Danilo Lombardo, takes a different route: Instead of asking what chemicals look like, the researchers asked what they do. They compiled nearly 10,000 environmental exposures, ranging from pollutants and food components to medications, and mapped how each affects human genes. The result is a large-scale network that links exposures based on shared biological effects.

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