From dancing to swimming, exercise may be one of the most effective—and overlooked—treatments for depression and anxiety.
Microsoft is investigating an outage that blocks some administrators with business or enterprise subscriptions from accessing the Microsoft 365 admin center.
While the company has yet to disclose which regions are affected by this ongoing service degradation, it is tracking it on its official service health status page to provide impacted organizations with up-to-date information.
“Some users in the North America region may be unable to access the Microsoft 365 admin center. We’re reviewing service monitoring telemetry to isolate the root cause and develop a remediation plan,” Microsoft said when it acknowledged the issue.
Miracle Mineral Solution, also known as MMS, has been marketed for years as a purported miracle cure for various conditions, including cancer, autism, and COVID-19. MMS is the marketing name for sodium chlorite (NaClO₂), a powerful disinfectant used, among other things, for water treatment. When sodium chlorite is acidified, chlorine dioxide (ClO₂) is formed. Its consumption can be hazardous to health.
A team of scientists from Wroclaw Medical University decided to investigate this.
In a study published in Scientific Reports, they analyzed the effects of acidified sodium chlorite (ASC), from which ClO₂ is produced.
Emilio Hirsch & team identify SH3BP5L as the most highly expressed guanine nucleotide exchange factor (GEF) for RAB11A, and its inhibition lowers lung metastasis and cell spreading in triple negative breast cancer models (TNBC):
The figure shows immunohistochemical assessment of SH3BP5L expression in tissue from patients with breast cancer.
@unito.it @fondazioneumbertoveronesi
1Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center “G. Tarone,” University of Torino, Torino, Italy.
2IEO, European Institute of Oncology IRCCS, Milan, Italy.
3Department of Oncology and Hemato-Oncology, University of Milano, Milano, Italy.
Medical artificial intelligence (AI) is often described as a way to make patient care safer by helping clinicians manage information. A new study by the Icahn School of Medicine at Mount Sinai and collaborators confronts a critical vulnerability: when a medical lie enters the system, can AI pass it on as if it were true?
Analyzing more than a million prompts across nine leading language models, the researchers found that these systems can repeat false medical claims when they appear in realistic hospital notes or social-media health discussions.
The findings, published in The Lancet Digital Health, suggest that current safeguards do not reliably distinguish fact from fabrication once a claim is wrapped in familiar clinical or social-media language. The paper is titled “Mapping LLM Susceptibility to Medical Misinformation Across Clinical Notes and Social Media.”
A new study by researchers at Kiel University and MPI-EvolBio describes how more efficient protein production drives the adaptation of fungi to the human body, potentially turning previously harmless species into emerging pathogens. In the wake of global change and the associated rise in temperatures, fungal infections are on the increase worldwide, threatening crops, wildlife and, also, human health. Many fungal species are completely harmless and fulfill important ecological functions, such as decomposing organic matter and releasing nutrients into the soil.
As symbionts of multicellular organisms, they perform useful functions for their host. On the other hand, some species are so-called opportunistic human pathogens: particularly in a weakened immune system, such fungi can colonize the body and cause serious and even life-threatening infections.
While fungi are often studied as pathogens of crops at institutions such as Kiel University and the Max Planck Institute for Evolutionary Biology in Plön (MPI-EvolBio), researchers are increasingly turning their attention to their harmful effects on humans. A research team led by Professor Eva Stukenbrock, head of the Environmental Genomics group at Kiel University and MPI-EvolBio, has conducted a new study to investigate why certain fungi might become human pathogens in the course of global change. To this end, the researchers analyzed various fungal species of the order Trichosporonales, which includes both harmless and dangerous species for humans.
In this nonrandomized clinical trial, the MUTTON-HF intervention incorporating Indigenous recipes and locally sourced Native food was feasible and acceptable for patients with heart failure in rural Navajo Nation.
Question Among Navajo patients with heart failure living rurally on the reservation, is a medically tailored meal delivery program incorporating Indigenous foods and recipes feasible and acceptable?
Findings This nonrandomized clinical trial included 20 American Indian patients with heart failure receiving care at 2 Indian Health Service sites in rural Navajo Nation. A community-designed, Indigenous, medically tailored meal program was implemented; the intervention was deemed both feasible (90% of weekly meal boxes received by patients) and acceptable (mean Acceptability of Intervention Measure score, 17 of 20).
In this systematic review and meta-analysis of EDI initiatives in health care institutions, programs were associated with an increased workforce diversity.
This systematic review and meta-analysis assesses equity, diversity, and inclusion initiatives in health care institutions that aimed to promote a more inclusive and equitable health care culture for individuals who beloing to racial and ethnic minority groups.
Antibiotic resistance (AR) has steadily accelerated in recent years to become a global health crisis. As deadly bacteria evolve new ways to elude drug treatments for a variety of illnesses, a growing number of “superbugs” have emerged, ramping up estimates of more than 10 million worldwide deaths per year by 2050.
Scientists are looking to recently developed technologies to address the pressing threat of antibiotic-resistant bacteria, which are known to flourish in hospital settings, sewage treatment areas, animal husbandry locations, and fish farms. University of California San Diego scientists have now applied cutting-edge genetics tools to counteract antibiotic resistance.
The laboratories of UC San Diego School of Biological Sciences Professors Ethan Bier and Justin Meyer have collaborated on a novel method of removing antibiotic-resistant elements from populations of bacteria. The researchers developed a new CRISPR-based technology similar to gene drives, which are being applied in insect populations to disrupt the spread of harmful properties, such as parasites that cause malaria. The new Pro-Active Genetics (Pro-AG) tool called pPro-MobV is a second-generation technology that uses a similar approach to disable drug resistance in populations of bacteria.