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Archive for the ‘health’ category: Page 11

Jul 29, 2020

In Search of Preventative Strategies: Novel Anti-Inflammatory High-CBD Cannabis Sativa Extracts Modulate ACE2 Expression in COVID-19 Gateway Tissues

Posted by in categories: biotech/medical, health

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Cannabis sativa, especially one high in the anti-inflammatory cannabinoid cannabidiol (CBD), has been proposed to modulate gene expression and inflammation and harbour anti-cancer and anti-inflammatory properties. Working under the Health Canada research license, we have developed over 800 new Cannabis sativa lines and extracts and hypothesized that high-CBD C. sativa extracts may be used to modulate ACE2 expression in COVID-19 target tissues. Screening C. sativa extracts using artificial human 3D models of oral, airway, and intestinal tissues, we identified 13 high CBD C. sativa extracts that modulate ACE2 gene expression and ACE2 protein levels. Our initial data suggest that some C. sativa extract down-regulate serine protease TMPRSS2, another critical protein required for SARS-CoV2 entry into host cells.

While our most effective extracts require further large-scale validation, our study is crucial for the future analysis of the effects of medical cannabis on COVID-19. The extracts of our most successful and novel high CBD C. sativa lines, pending further investigation, may become a useful and safe addition to the treatment of COVID-19 as an adjunct therapy. They can be used to develop easy-to-use preventative treatments in the form of mouthwash and throat gargle products for both clinical and at-home use. Such products ought to be tested for their potential to decrease viral entry via the oral mucosa. Given the current dire and rapidly evolving epidemiological situation, every possible therapeutic opportunity and avenue must be considered.

Continue reading “In Search of Preventative Strategies: Novel Anti-Inflammatory High-CBD Cannabis Sativa Extracts Modulate ACE2 Expression in COVID-19 Gateway Tissues” »

Jul 29, 2020

Newer PFAS compound detected for first time in Arctic seawater

Posted by in categories: biotech/medical, food, health

This sucks.


Per- and polyfluoroalkyl substances (PFAS), found in many household products and food packages, have raised concerns because of their persistence and possible toxicity to people and wildlife. Because the compounds don’t break down naturally, they have become environmental contaminants. Now, researchers reporting in Environmental Science & Technology have studied the transport of 29 PFAS into and out of the Arctic Ocean, detecting a newer compound for the first time in Arctic seawater.

After studies indicated that two PFAS—PFOA and PFOS—can cause cancer, a compromised immune response and other health problems in lab animals, the two compounds were voluntarily phased out by industry. However, these legacy compounds are still widely detected in the environment. Intended as a safer replacement for PFOA, HFPO-DA (sold under the trade name GenX) is now thought to pose similar health and persistence concerns. Hanna Joerss and colleagues wanted to investigate the long-range, oceanic transport of legacy and replacement PFAS to the Arctic Ocean—a remote body of water connected to the Atlantic Ocean by the Fram Strait, which is located between Svalbard and Greenland.

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Jul 28, 2020

Artificial intelligence to enable fast-track review of COVID-19 research proposals

Posted by in categories: biotech/medical, health, robotics/AI

An Artificial Intelligence tool to help funders identify specialists to peer-review proposals for emergency research has been developed by Frontiers. It aims to help fast-track the allocation of funding, and in turn, accelerate the scientific response.


An Artificial Intelligence (AI) tool to help funders identify specialists to peer-review proposals for emergency COVID-19 research has been developed. It aims to help fast-track the allocation of funding, and in turn, accelerate the scientific response to the virus.

The open-access publisher Frontiers has specifically developed the recommendation tool to aid funders during the crisis by helping them identify new reviewers. Under normal circumstances, the review process for research funding typically takes place by committee and can take a matter of months. However, since the COVID-19 outbreak, experts have become less available, and the urgency of this situation commands a tighter timeframe.

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Jul 28, 2020

Machine learning predicts satisfaction in romantic relationships

Posted by in categories: health, information science, robotics/AI

The most reliable predictor of a relationship’s success is partners’ belief that the other person is fully committed, a Western University-led international research team has found.

Other in a successful include feeling close to, appreciated by, and sexually satisfied with your partner, says the study—the first-ever systematic attempt at using machine-learning algorithms to predict people’s relationship satisfaction.

“Satisfaction with has important implications for health, wellbeing and work productivity,” Western Psychology professor Samantha Joel said. “But research on predictors of relationship quality is often limited in scope and scale, and carried out separately in individual laboratories.”

Jul 27, 2020

Researchers Use Pencil to Draw Bioelectronic Devices on Human Skin

Posted by in categories: biotech/medical, chemistry, health

Scientists from the University of Missouri, the University of Illinois and Yale University have demonstrated that a combination of pencils and paper could be used to create on-skin bioelectronic devices that might be used to monitor personal health. They’ve fabricated and evaluated a rich variety of pencil-paper-based bioelectronic devices, ranging from biophysical sensors and sweat biochemical sensors to thermal stimulators, ambient humidity energy harvesters, and transdermal drug-delivery systems.

Jul 27, 2020

Artificial Intelligence Identifies Prostate Cancer With Near-Perfect Accuracy

Posted by in categories: biotech/medical, health, information science, robotics/AI

A study published today (July 27, 2020) in The Lancet Digital Health by UPMC and University of Pittsburgh researchers demonstrates the highest accuracy to date in recognizing and characterizing prostate cancer using an artificial intelligence (AI) program.

“Humans are good at recognizing anomalies, but they have their own biases or past experience,” said senior author Rajiv Dhir, M.D., M.B.A., chief pathologist and vice chair of pathology at UPMC Shadyside and professor of biomedical informatics at Pitt. “Machines are detached from the whole story. There’s definitely an element of standardizing care.”

To train the AI to recognize prostate cancer, Dhir and his colleagues provided images from more than a million parts of stained tissue slides taken from patient biopsies. Each image was labeled by expert pathologists to teach the AI how to discriminate between healthy and abnormal tissue. The algorithm was then tested on a separate set of 1,600 slides taken from 100 consecutive patients seen at UPMC for suspected prostate cancer.

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Jul 26, 2020

Reducing Sugar Uptake Increased Cancer Cells’ Sensitivity to Chemotherapy

Posted by in categories: biotech/medical, health

People often talk about sugar intake and health 🤔

Researchers have successfully increased cancer cells’ sensitivity to chemotherapy to prevent glucose from entering the cancer cell.


Researchers at Lund University in Sweden have successfully increased cancer cells’ sensitivity to chemotherapy by preventing sugar uptake. Their study, “Targeting Glut1 In Acute Myeloid Leukemia To Overcome Cytarabine Resistance,” is published in Haematologica.

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Jul 25, 2020

Mould from Chernobyl nuclear reactor tested as radiation shield on ISS

Posted by in categories: health, nuclear energy, space

A radiation-absorbing fungus found at the destroyed Chernobyl nuclear reactor has been shown to absorb harmful cosmic rays on the International Space Station, and could potentially be used to protect future Mars colonies.

Exposure to cosmic rays poses a major health risk to astronauts leaving Earth’s protective atmosphere. Shields can be made out of stainless steel and other materials, but they must be shipped from Earth, which is difficult and costly.

Jul 25, 2020

How About a Space Station at the Bottom of the Ocean?

Posted by in categories: health, materials

Jacques Cousteau’s grandson is pushing for the construction of a real-life Sealab 2021. The proposed undersea laboratory is so foreign to our idea of marine studies that it’s being likened to a space station that’s also under the ocean.

The station is named Proteus, not for the changing nature of matter (like a new uncuttable material with the same name), but for the shepherd of the sea. By placing a station 60 feet underwater around the Caribbean island of Curacao, sponsoring Northeastern University says it can reduce divers’ high amount of overhead time and reduce the danger of nitrogen-induced health effects.

Jul 25, 2020

NASA: Virtual Guest Mars 2020 Perseverance

Posted by in categories: biotech/medical, health, robotics/AI

We’re going back to Mars, and we’d like you to be our virtual guest on the trip. On July 30, NASA will launch the Mars 2020 Perseverance rover on a seven-month journey to the Red Planet. After landing in Jezero Crater, the robotic astrobiologist and scientist will search for signs that microbes might have lived on Mars long ago, collect soil samples to be returned to Earth on a future mission and pave the way for human exploration beyond the Moon. Perseverance will be accompanied by a helicopter called Ingenuity, the first attempt at powered flight on another world.

Because of the coronavirus pandemic and in the interest of health and safety, NASA can’t invite you to Florida to watch the launch personally. However, there are many ways you can participate virtually:

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