Toggle light / dark theme

People with pockets of fat hidden inside their muscles are at a higher risk of dying or being hospitalized from a heartattack or heart failure, regardless of their body mass index, according to research published in the European Heart Journal.

This ‘intermuscular’ fat is highly prized in beef steaks for cooking. However, little is known about this type of body fat in humans, and its impact on health. This is the first study to comprehensively investigate the effects of fatty muscles on heart disease.

The new finding adds evidence that existing measures, such as body mass index or waist circumference, are not adequate to evaluate the risk of heart disease accurately for all people.

Physical fitness is typically associated with health benefits, and we generally consider exercise good. Many studies have shown that this relates to cancer, where exercise and maintaining a healthy weight can reduce the risk of developing cancer. Studies have shown that obesity raises the risk of mortality in cancer patients.

Data recently published in the British Journal of Sports Medicine suggests that staying fit could reduce the risk of dying from cancer. The study looked at two different readouts for fitness: muscle strength and cardiorespiratory fitness (CRF).

The researchers undertook a comprehensive review and meta-analysis by examining peer-reviewed studies published before August 2023. The analysis included 42 studies encompassing over 46,000 patients.

Has NASA canceled the SLS moon rocket? Will the Artemis Program be canceled too? Can we still beat China to the moon? See why that is vital and my role in helping to establish both the commercial space and SLS programs.

GoldBacks from Galactic/Green Greg’s affiliate link:
https://www.defythegrid.com/goldbacks… coupon code GreenGregs for 1% off Outstanding Antioxidant for Your Health: https://shopc60.com/ Use discount code: GreenGregs10 for 10% off Inspire your kids to love science! SAVE 20% OFF New Science Kits Using Code: NEWKITSSAVE20 https://www.pntra.com/t/SENKTExNSUhDR… For gardening in your Lunar or Mars habitat GalacticGregs has teamed up with True Leaf Market http://www.pntrac.com/t/TUJGRklGSkJGT… Awesome deals for long term food supplies for those long missions to deep space (or prepping in case your spaceship crashes: See the Special Deals at My Patriot Supply: www.PrepWithGreg.com For that off-grid asteroid homestead stock up with Lemans before you blast off: https://www.pntrs.com/t/SENJR0ZOSk9DR

Earth sized planet causes parent star to emit radio signals indicating presence of a magnetic field and potential for live elsewhere in the cosmos.

GoldBacks from Galactic/Green Greg’s affiliate link:
https://www.defythegrid.com/goldbacks… coupon code GreenGregs for 1% off Outstanding Antioxidant for Your Health: https://shopc60.com/ Use discount code: GreenGregs10 for 10% off Inspire your kids to love science! SAVE 20% OFF New Science Kits Using Code: NEWKITSSAVE20 https://www.pntra.com/t/SENKTExNSUhDR… For gardening in your Lunar or Mars habitat GalacticGregs has teamed up with True Leaf Market http://www.pntrac.com/t/TUJGRklGSkJGT… Awesome deals for long term food supplies for those long missions to deep space (or prepping in case your spaceship crashes: See the Special Deals at My Patriot Supply: www.PrepWithGreg.com For that off-grid asteroid homestead stock up with Lemans before you blast off: https://www.pntrs.com/t/SENJR0ZOSk9DR

The Sustainable Development Goals (SDGs) constitute the leading global framework for achieving human progress, economic prosperity, and planetary health. This framework emphasizes issues such as public health, education for all, gender equality, zero hunger, adoption of clean and renewable energy, and biodiversity conservation. Yet, despite this comprehensive agenda, questions remain about how different nations navigate their own paths toward these goals.

A recent study, published in Nature Communications provides insights into the trajectories of 166 countries as they have worked toward the SDGs over the past two decades.

By applying and the Product Space methodology, commonly used in the field of complexity economics, the researchers constructed the “SDG Space of Nations.” The elaborate model shows that countries do not simply march in lockstep toward sustainable development; instead, they cluster into distinctive groups, each with its own strengths and specializations, sometimes quite unexpected.

Almost 2% chance for catastrophic impact in 7 years? What should we do?


GoldBacks from Galactic/Green Greg’s affiliate link:

Goldbacks


Use coupon code GreenGregs for 1% off.

Outstanding Antioxidant for Your Health: https://shopc60.com/
Use discount code: GreenGregs10 for 10% off.

Inspire your kids to love science!
SAVE 20% OFF New Science Kits Using Code: NEWKITSSAVE20 https://www.pntra.com/t/SENKTExNSUhDR05OSUxJQ0dPRkxGRw.

For gardening in your Lunar or Mars habitat GalacticGregs has teamed up with True Leaf Market http://www.pntrac.com/t/TUJGRklGSkJGTU1IS0hCRkpIRk1K

A 2020 assessment of IKN by the National Planning and Development Agency highlighted the risks, citing data including the abundance of disease-carrying mosquitoes. At least two construction workers caught malaria in 2022 while at the site, according to the Ministry of Health. Last year, 54 cases were reported there, but the ministry claimed the patients were infected elsewhere. Although the construction authority has taken some control measures, such as handing out mosquito nets to workers, it’s not well-equipped for the job, says Mirza Buana, a legal scholar at Lambung Mangkurat University in South Kalimantan: “It has all the authorities but no capabilities.” The agency has shifted most of the tasks—such as vector control and screening workers entering or leaving IKN—to district health officials, who have struggled to keep up.

Surendra is particularly worried about the potential spread of P. knowlesi, a parasite first discovered in the 1930s. It emerged as a public health threat in the early 2000s, in areas in the Malaysian part of Borneo where forests were cleared for oil palm plantations. It has since been identified in many Southeast Asian countries.

P. knowlesi primarily infects long-tailed macaques, highly adaptable monkeys that thrive at the forest edge, and is spread by forest-dwelling Anopheles mosquitoes that occasionally bite humans as well. People working in or near the forest, including hunters and loggers, are at the highest risk. Because it has an animal reservoir, the disease is impossible to eliminate completely. Mosquitoes don’t transmit P. knowlesi between people—or very poorly—but some scientists worry that could change.

Synthetic biologists from Yale were able to re-write the genetic code of an organism—a novel genomically recoded organism (GRO) with one stop codon—using a cellular platform that they developed enabling the production of new classes of synthetic proteins. These synthetic proteins, researchers say, offer the promise of innumerable medical and industrial applications that can benefit society and human health.

The creation of the landmark GRO, known as “Ochre”—which fully compresses redundant, or “degenerate” codons, into a single codon—is described in a new study published in the journal Nature. A codon is a sequence of three nucleotides in DNA or RNA that codes for a specific amino acid, which serves as the biochemical building blocks for proteins.

“This research allows us to ask fundamental questions about the malleability of genetic codes,” said Farren Isaacs, professor of molecular, cellular and at Yale School of Medicine and of biomedical engineering at Yale’s Faculty of Arts and Sciences, who is co-senior author of the paper. “It also demonstrates the ability to engineer the genetic code to endow multi-functionality into proteins and usher in a new era of programmable biotherapeutics and biomaterials.”

The study of ‘starquakes’ (like earthquakes, but in stars) promises to give us important new insights into the properties of neutron stars (the collapsed remnants of massive stars), according to new research led by the University of Bath in the UK.

Such explorations have the potential to challenge our current approaches to studying , with important impacts for the future of both nuclear physics and astronomy. Longer term, there may also be implications in the fields of health, security and energy.

The value of studying asteroseismology—as these vibrations and flares are known—has emerged from research carried out by an international team of physicists that includes Dr. David Tsang and Dr. Duncan Neill from the Department of Physics at Bath, along with colleagues from Texas A&M and the University of Ohio.

The rise of antimicrobial resistance has rendered many treatments ineffective, posing serious public health challenges. Intracellular infections are particularly difficult to treat since conventional antibiotics fail to neutralize pathogens hidden within human cells. However, designing molecules that penetrate human cells while retaining antimicrobial activity has historically been a major challenge. Here, we introduce APEXDUO, a multimodal artificial intelligence (AI) model for generating peptides with both cell-penetrating and antimicrobial properties. From a library of 50 million AI-generated compounds, we selected and characterized several candidates. Our lead, Turingcin, penetrated mammalian cells and eradicated intracellular Staphylococcus aureus. In mouse models of skin abscess and peritonitis, Turingcin reduced bacterial loads by up to two orders of magnitude. In sum, APEXDUO generated multimodal antibiotics, opening new avenues for molecular design.

CFN provides consulting services to Invaio Sciences and is a member of the Scientific Advisory Boards of Nowture S.L., Peptidus, European Biotech Venture Builder and Phare Bio. CFN is also a member of the Advisory Board for the Peptide Drug Hunting Consortium (PDHC). The de la Fuente Lab has received research funding or in-kind donations from United Therapeutics, Strata Manufacturing PJSC, and Procter & Gamble, none of which were used in support of this work. An invention disclosure associated with this work has been filed. All other authors declare no competing interests.