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Category: health – Page 10

Brains of teens with autism ‘tune in’ less to unfamiliar voices, study finds

Like other teenagers, teens on the autism spectrum are itching to exercise their social muscles. They hope for new friends, fun with people who share their interests, maybe even a romantic relationship.

“Adolescence is a moment of opportunity for these kids,” said Daniel Abrams, Ph.D., clinical associate professor of psychiatry and behavioral sciences at Stanford Medicine. “They want to build friendships.”

But spreading their social wings is challenging for teens with autism. A new Stanford Medicine-led study, published in Proceedings of the National Academy of Sciences, sheds light on a key factor: how the brains of teenagers with autism handle the sounds of unfamiliar voices. Unlike neurotypical teenagers, the reward centers in autistic teens’ brains don’t become increasingly responsive to strangers’ voices as they mature, the research found.

MIT engineers whip up a more breathable hydrogel

For all their sticky, stretchy, and protective properties, hydrogels lack one key trait: breathability. If worn for too long, a bandage or patch can trap moisture and sweat, which can irritate tissues and reduce the effectiveness of any device that a hydrogel adheres.

Now MIT engineers have come up with a recipe for a hydrogel that is both hydrated and aerated, or permeable to air. The new material is just as soft, stretchy, and robust as conventional hydrogels, but a network of tiny tunnels running through the gel allows air to pass through.

The aerated hydrogel can be worn for longer periods of time compared to conventional hydrogels, without causing skin irritation. It can also reduce sweat buildup, even during exercise. In experiments, volunteers wore wireless heart monitors that were attached to their chest with the new breathable hydrogel. After working out regularly for 10 days, the volunteers showed no signs of skin irritation, and the heart monitors maintained clear readings.

When back pain won’t quit: A large clinical trial points to the power of self-management

Almost everyone will deal with back pain at some point in their lives. Most recover quickly—but for about 20% of people, acute pain becomes a chronic condition that interferes with daily life and keeps them out of the workforce.

Low back pain is one of the leading causes of disability worldwide, and more money is spent managing it in the United States than any other health condition. Despite that, the most effective way to prevent a short-term episode from becoming a long-term problem has not been clear—especially for people who are most at risk.

“Chronic low back pain prevention is a public health issue,” said Michael Schneider, D.C., Ph.D., professor in the School of Health and Rehabilitation Sciences at the University of Pittsburgh and co-principal investigator of the Pitt arm of the study. “The 20% of patients who turn chronic account for 80% of the costs and the suffering. This paper shows that helping people self-manage their pain through a properly trained physical therapist or chiropractor is a great way to mitigate this public health problem.”

Experimental drug reverses severe fatty liver disease by repairing the gut

An experimental drug developed at Michigan Medicine has shown the ability to reverse severe fatty liver disease in animal studies by restoring gut health. The findings, published in The Journal of Clinical Investigation, suggest that targeting the connection between the gut and liver could offer a promising new approach for treating metabolic dysfunction-associated steatohepatitis (MASH).

MASH is a serious form of fatty liver disease that affects about 7% of people worldwide. It can progress to cirrhosis, liver cancer, and liver failure, yet effective treatment options remain limited.

The investigational compound, known as DT-109, is a glycine-based tripeptide. Researchers found that it reversed MASH in animal models by interrupting a harmful biological process linking the gut and liver.

SensorFM: Towards a general intelligence and interface for wearable health data

We present SensorFM, a foundation model for wearable health pre-trained on more than one trillion minutes of sensor data from five million people. By co-scaling model size and data, SensorFM learns a general-purpose representation of human physiology that transfers to 35 health prediction tasks, supports label-efficient adaptation and data infilling, and can serve as a grounding tool for a Personal Health Agent.

Is AI making us stupid?

Not exactly—but how we use it matters.

A new Trends in Cognitive Sciences perspective argues that AI doesn’t inherently erode human intelligence. Instead, it highlights a well-known principle in cognitive psychology: cognitive offloading.

When we let AI perform tasks that require reasoning, writing, memory, or problem-solving, we reduce the amount of mental practice our brains receive. Like physical exercise, cognitive skills strengthen through use and weaken through disuse.

Skills: learned abilities such as writing, mathematical reasoning, diagnosis, or programming. These are most vulnerable if AI consistently replaces the learning process.

Basic cognitive abilities: foundational functions like working memory, attention, and executive control. Current evidence suggests these may be more resistant to decline, although more research is needed.

The key message isn’t that AI makes people “stupid.” Rather: AI can improve immediate performance. Overreliance may reduce long-term learning and skill retention.

AI is most beneficial when it augments human thinking instead of replacing it. This fits with decades of neuroscience showing that practice drives neuroplasticity. The brain adapts to the cognitive demands we place on it. If.

Continue reading “Is AI making us stupid?” | >

New soft wearable device could support at-home sleep monitoring

Good sleep is essential for brain health. During sleep and rest, the glymphatic system, the brain’s waste-clearing process, helps remove metabolic waste that accumulates during waking hours. This activity is linked to memory processing, cognitive function and neural recovery. When sleep quality is poor, metabolic waste may accumulate, potentially disrupting cognitive function and memory formation.

Traditional approaches to brain monitoring are often invasive, costly and limited to clinical settings. New research from Georgia Tech points to a more accessible approach. A study published in Science Advances shows that a soft, wireless wearable device could help enable home-based monitoring of physiological changes associated with sleep and brain health.

The research team, led by W. Hong Yeo, Peterson Endowed Professor in the Woodruff School of Mechanical Engineering and director of the Wearable Intelligent Systems and Healthcare Center and the Korea KIAT-Georgia Tech Semiconductor Electronics Center, developed a wearable device that uses light-based sensing and wireless communication to support natural sleep monitoring at home.

Genetic mapping identifies new hope for bone diseases

In a global breakthrough published in Nature Genetics, researchers have successfully mapped the cells and genes that regulate bone formation and loss at an unprecedented scale and discovered the critical role that blood vessel cells play in bone health.

By combining genomic sequencing with data from half a million individuals, the research team identified hundreds of previously unknown genes that govern bone health and revealed cells surrounding blood vessels as one of the drivers of bone repair—a role that has been underappreciated until now.

Led by Professor Peter Croucher and Dr. Ryan Chai from the Garvan Institute of Medical Research, Associate Professor John Kemp from Mater Research, and Professor Graham Williams and Professor Duncan Bassett from Imperial College London, the team’s findings fundamentally enhance our understanding of skeletal disease.

Quantum optics may turn this rare visual phenomenon into an eye test

Modern life depends on quantum physics. It makes technologies such as GPS navigation, MRI scanners and computer chips possible. Now, the same science may also lead to a new way to test the health of our eyes. A University at Buffalo-led team has used a technique from quantum optics to make a little-known visual pattern produced inside the eye easier to see—potentially opening the door to a new way to test retinal health.

Known as Boehm’s brushes, these faint, two-lobed, bowtie-shaped patterns sometimes appear in peripheral vision when polarized light scatters off structures in the retina. Because people with retinal disease may be less likely to perceive them, scientists have long wondered whether they could serve as a biomarker of retinal health.

However, Boehm’s brushes are often too hard to see, even for people with healthy eyes, to be useful in clinical practice.

The silent hormone: How adrenal tumors quietly raise cardiovascular risk over time

A major new study, published in The Lancet Diabetes & Endocrinology, has shown that cortisol levels in patients with adrenal tumors are far less stable than previously assumed. The study also found that those in whom cortisol remains persistently elevated carry a significantly greater risk of worsening high blood pressure and a heavier overall cardiometabolic burden.

Cortisol, often referred to as the “stress hormone,” is a steroid hormone produced by the adrenal glands that acts as a master regulator of metabolism, blood pressure and immune function. When benign tumors form on the adrenal glands (found incidentally in 3%–7% of adults), they can cause the body to produce cortisol independently of normal regulatory controls, a condition known as mild autonomous cortisol secretion (MACS).

Until now, it was unclear how cortisol levels in these patients change over time, and what that means for their long-term health.

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