Archive for the ‘genetics’ category: Page 92
Dec 25, 2022
Tiny New Genes Appearing in Human DNA Show How We’re Still Evolving
Posted by Shubham Ghosh Roy in categories: biotech/medical, genetics
We may have parted ways with our primate cousins millions of years ago, but a new study shows just how human beings continue to evolve in ways we never imagined.
Researchers from Biomedical Sciences Research Center “Alexander Fleming” (BSRC Flemming) in Greece and Trinity College Dublin, Ireland, have identified 155 genes in our genome that emerged from small, non-coding sections of DNA. Many appear to play a critical role in our biology, revealing how completely novel genes can rapidly evolve to become essential.
New genes typically arise through well known mechanisms like duplication events, where our genetic machinery accidently produces copies of pre-existing genes that can end up suiting new functions over time.
Dec 25, 2022
Documentary spurs a new look at the case of the first gene-edited babies
Posted by Dan Breeden in categories: biotech/medical, education, genetics
In the four years since an experiment by disgraced scientist He Jiankui resulted in the birth of the first babies with edited genes, numerous articles, books and international commissions have reflected on whether and how heritable genome editing—that is, modifying genes that will be passed on to the next generation—should proceed. They’ve reinforced an international consensus that it’s premature to proceed with heritable genome editing. Yet, concern remains that some individuals might buck that consensus and recklessly forge ahead—just as He Jiankui did.
Dec 24, 2022
Groundbreaking: Baby girl successfully treated for genetic disease before birth
Posted by Paul Battista in categories: biotech/medical, genetics
Two of Ayla’s siblings had died early in life due to the same disease. But infusions given from 24–36 weeks in utero appears to have saved Ayla’s life.
Dec 24, 2022
Could We Really Increase Human IQ via Genetic Engineering?
Posted by Dan Breeden in categories: bioengineering, ethics, genetics
It’s not clear what, explicitly, human intelligence is or even how it originates. Ethics aside, there’s no way to decide who to save and who to throw away.
Dec 23, 2022
Quantifying Biological Age: Blood Test #7 in 2022
Posted by Mike Lustgarten in categories: biotech/medical, genetics, life extension
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Dec 22, 2022
De novo birth of functional microproteins in the human lineage
Posted by Saúl Morales Rodriguéz in categories: biotech/medical, evolution, genetics
Human microproteins encoded by small ORFs have been found to be functional. By comparing the corresponding sequences across vertebrate genomes, Vakirlis et al. show that a number of these originated “from scratch” from noncoding sequences, including two very recent cases unique to humans. These cases demonstrate the rapid evolution of genetic novelty.
Dec 22, 2022
In a first, scientists produced male and female cells from a single person
Posted by Gemechu Taye in categories: biotech/medical, genetics, sex
It will provide a better understanding of how drugs affect men and women differently.
Scientists created male and female cells with the same genetic code from the same person for the first time. This unique set of cells could provide researchers with valuable insights into how sex chromosomes affect various diseases and their role in early development.
CDC/Dr. Laine.
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Dec 22, 2022
Gene therapy could save children from a rare genetic disease
Posted by Gemechu Taye in categories: biotech/medical, genetics
This impressive achievement could potentially revolutionize how we treat cancer and immunity deficiencies.
Children born with Artemis-SCID face many challenges, from a missing repertoire of T and B cells to reduced resistance against chemotherapy used in bone marrow transplants. Additionally, malfunctioning DNA repair mechanisms increase the risk of developing graft-versus-host disease, where the donor’s immune system attacks host tissues.
That’s why researchers are trying everything to find an antidote for such a rare genetic disease and have now turned to gene therapy to treat Artemis-SCID. Gene therapy eliminates the need for donor cells.
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Dec 22, 2022
Robust Mouse Rejuvenation project details announced
Posted by Shubham Ghosh Roy in categories: biotech/medical, genetics, life extension
The newly-created Longevity Escape Velocity Foundation (LEV) has released details of the first study in its flagship research programme: Robust Mouse Rejuvenation – Study 1.
Longevity. Technology: A highlight of Longevity Summit Dublin 2022 was Dr Aubrey de Grey’s announcement of his new foundation; LEV Foundation exists to proactively identify and address the most challenging obstacles on the path to the widespread availability of genuinely effective treatments to prevent and reverse human age-related disease, and to that end, its flagship research programme is a sequence of large mouse lifespan studies.
Mouse models are significant in aging research for several reasons. Mice and humans share many genetic and physiological similarities, including similar aging-related pathways, and this makes mice a useful model for studying the molecular and cellular processes underlying aging in humans.