Lifeboat Foundation

BERLIN — A biotechnologist in Germany is developing the world’s first artificial womb facility, and it lets you choose baby’s characteristics from a menu. EctoLife, able to grow 30,000 babies a year, is said to be based on over fifty years of groundbreaking scientific research.

The concept is the brainchild of Berlin-based Hashem Al-Ghaili. He says the facilities would allow infertile couples to conceive a baby and become the true biological parents of their own offspring.

A so-called ‘Elite Package’ would allow you to genetically engineer the embryo before implanting it into the artificial womb. Everything from eye and hair color to strength, height, and intelligence can be chosen, and inherited genetic diseases can be avoided.

It was once thought that inflammation and immune responses in the brain were limited; that is was a so-called immune privileged organ. But there is increasing evidence to the contrary. New research has shown that immune cells called mucosal-associated invariant T cells (MAITs) can serve critical roles in the brain that reduce the levels of damaging reactive oxygen species, which prevents neuroinflammation, and protects learning and memory. The findings have been reported in Nature Immunology.

In this study, researchers genetically engineered mice so MAITs would no longer be produced. These mice were compared to a normal group and mice and while cognitive function was the same in both groups to start with, difference appeared as the mice approached middle age. The MAIT-deficient mice had difficulty forming new memories.

But even junk has hidden treasures. Studies found variations in these unsequenced regions were intricately involved in human health, from aging to conditions like cancer and developmental disorders like autism. In 2022, a landmark study finally resolved the genomic unknown, completely sequencing the remaining eight percent of undeciphered DNA remaining.

Now, scientists are discovering that some genetic sequences encode proteins that lack any obvious ancestors, what geneticists call orphan genes. Some of these orphan genes, the researchers surmise, arose spontaneously as we evolved, unlike others that we inherited from our primate ancestors. In a paper published Tuesday in the journal Cell Reports, researchers in Ireland and Greece found around 155 of these smaller versions of DNA sequences called open reading frames (or ORF) make microproteins potentially important to a healthy cell’s growth or connected to an assortment of ailments like muscular dystrophy and retinitis pigmentosa, a rare genetic disease affecting the eyes.

“This is, I think, the first study looking at the specific evolutionary origins of these small ORFs and their microproteins,” Nikolaos Vakirlis, a scientist at the Biomedical Sciences Research Center “Alexander Fleming” in Greece and first author of the paper, tells Inverse. It’s an origin, he says, that’s been mired in much question and mystery.

Investigators from the Smidt Heart Institute at Cedars-Sinai have identified how biological pacemaker cells—cells that control your heartbeat—can “fight back” against therapies to biologically correct abnormal heartbeat rates. The research also uncovered a new way to boost the effectiveness of RNA therapies by controlling this “fighting back” activity.

This novel concept, published today in the peer-reviewed journal Cell Reports Medicine, is an important step in the evolution and creation of biological pacemakers—which aim to one day replace traditional, electronic pacemakers.

“We are all born with a specialized group of heart cells that set the pace for our heartbeats,” said Eugenio Cingolani, MD, senior author of the study and director of the Cardiogenetics Program in the Smidt Heart Institute at Cedars-Sinai. “But in some people, this natural heartbeat is too slow, leading to the need for an electronic pacemaker.”

This video explores the timelapse of artificial intelligence from 2030 to 10,000A.D.+. Watch this next video about Super Intelligent AI and why it will be unstoppable: https://youtu.be/xPvo9YYHTjE
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SOURCES:
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• The Singularity Is Near: When Humans Transcend Biology (Ray Kurzweil): https://amzn.to/3ftOhXI
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Continue reading “FUTURE OF ARTIFICIAL INTELLIGENCE (2030 — 10,000 A.D.+)” »

Transhumanism advocates the use of current and emerging technologies such as genetic engineering, artificial intelligence, and nanotechnology, to augment human capabilities, enhance longevity, and improve cognition. The term “designer baby” refers to a child who would develop from an embryo or sperm or egg that had been genetically altered. Is there a covert political agenda behind this allegedly altruistic scientific movement?

Robert Sepehr is an anthropologist and author.
(books also available through other book outlets)
http://amazon.com/Robert-Sepehr/e/B00XTAB1YC/

Continue reading “Transhumanism and Human Genetic Engineering — ROBERT SEPEHR” »

Summary: Findings support the theory that microRNAs are essential for the development and evolution of intelligent life.

Source: Dartmouth College.

Octopuses have captured the attention of scientists and the public with their remarkable intelligence, including the use of tools, engaging in creative play and problem-solving, and even escaping from aquariums.

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Continue reading “L. plantarum Increases Muscle Mass And Physical Function (Part II)” »

Biophysist and Biochemist Dr. Maximilian Plach talks about a groundbreaking new technology for editing genes, called CRISPR-Cas9. The tool allows scientists to make precise edits to DNA strands, which could lead to treatments for genetic diseases … but could also be used to create so-called “designer babies.” Max reviews how CRISPR-Cas9 works — and asks the scientific community to pause and discuss the ethics of this new tool. Max has earned his PhD in biophysics and computational biology at the University of Regensburg, Germany. He is now Chief Scientific Officer of 2bind, a dynamic and growing company focused on providing biophysical research services for biotech and pharma industries. It is therefore no wonder that Max closely follows the latest breakthroughs and developments in biotech and biomedical technology. He is a long viewer and listener of TED talks; the more exotic, the better. Or who doesn’t remember the talk about the world’s worst city flags? This talk was given at a TEDx event using the TED conference format but independently organized by a local community.