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Scientists at Tel Aviv University in Israel have developed a “cyborg heart patch” for replacing injured cardiac tissue. There has been considerable research on creating scaffolds seeded with cardiac cells, but simply delivering a bunch of cells in a neat package produces underwhelming results. The new patch developed at TAU integrates electronics alongside the cellular scaffold to both monitor and influence the activity of the cells.

The device can record intercellular electrical activity and deliver pulses to make the cardiomyocytes contract to a defined beat. Additionally, the researchers demonstrated that the electrodes within the patch can be covered with drugs to provide controlled release of medication right to the nearby heart cells.

This is certainly an impressive achievement that may herald a truly therapeutic approach for treating cardiac infarcts and other conditions of the heart.

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Making the most of the low light in the muddy rivers where it swims, the elephant nose fish survives by being able to spot predators amongst the muck with a uniquely shaped retina, the part of the eye that captures light. In a new study, researchers looked to the fish’s retinal structure to inform the design of a contact lens that can adjust its focus.

Imagine a that autofocuses within milliseconds. That could be life-changing for people with presbyopia, a stiffening of the eye’s that makes it difficult to focus on close objects. Presbyopia affects more than 1 billion people worldwide, half of whom do not have adequate correction, said the project’s leader, Hongrui Jiang, Ph.D., of the University of Wisconsin, Madison. And while glasses, conventional contact lenses and surgery provide some improvement, these options all involve the loss of contrast and sensitivity, as well as difficulty with night vision. Jiang’s idea is to design contacts that continuously adjust in concert with one’s own cornea and lens to recapture a person’s youthful vision.

The project, for which Jiang received a 2011 NIH Director’s New Innovator Award (an initiative of the NIH Common Fund) funded by the National Eye Institute, requires overcoming several engineering challenges. They include designing the lens, algorithm-driven sensors, and miniature electronic circuits that adjust the shape of the lens, plus creating a power source — all embedded within a soft, flexible material that fits over the eye.

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One of the latest inventions out of Tel Aviv University can patch up broken hearts. We’re talking about the real organs here, especially those damaged by myocardial infarction or heart attack. A team from the Israeli university created a “cyborg heart patch” that combines both living tissue and electronic components to replace the damaged parts of the organ. “It’s very science fiction, but it’s already here,” says one of its creators, Prof. Tal Dvir. “[W]e expect it to move cardiac research forward in a big way.” The patch can contract and expand like real heart tissue can, but it can do much, much more than that.

The electronic components allow doctors to remotely monitor their patients’ condition from afar. A physician could log into a computer and see if the implant is working as intended. If he senses that something’s amiss, he could release drugs to, say, regulate inflammation or fix the lack of oxygen. That sounds dangerous to us, since computers can be hacked. But the researchers are aiming to develop the patch further so it can regulate itself with no human intervention.

Dvir warns that the “practical realization of the technology may take some time.” For now, those suffering from cardiovascular diseases will have to rely on current treatment methods. The team is still in the midst of refining their cyborg heart patch. Plus, they’re looking at how to create bionic brain and spinal cord tissues using what they’ve learned so far to treat neurological conditions.

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Interesting — DNA Microchips to be released soon.


Researchers presented this incredible work at the national meeting and exposition of the American Chemical Society (ACS) in San Diego, California, on Sunday.

Adam T Woolley, professor of chemistry at Brigham Young University (BYU) said that they are planning to use DNA’s small size and base-pairing capabilities and ability to self-assemble, and direct it to make nanoscale structures that could be used for electronics.

“The problem, however, is that DNA does not conduct electricity very well. So we use the DNA as a scaffold and then assemble other materials on the DNA to form electronics,” Woolley added.

Scientists has opened a door to faster, cheaper computer chips with the help of ‘DNA origami.’ “We would like to use DNA’s very small size, base-pairing capabilities and ability to self-assemble, and direct it to make nanoscale structures that could be used for electronics,” Adam T. Woolley said.

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