Toggle light / dark theme

Genome study reveals centromeres as one of the fastest-changing regions in human DNA

A centromere is a specific region on a chromosome that ensures that, when a cell divides, the chromosome separates accurately so each new cell receives the correct amount of genetic material. Despite their essential role, centromeres remain one of the last major blind spots in the human genome.

A recent study published in Nature set out to reveal what had been hidden inside human centromeres, using advanced long-read sequencing and custom-built computational tools to piece together 2,110 complete centromeres. The researchers sampled individuals from 28 population groups across five continents, then compared their centromeres with 5,747 assembled by the Human Pangenome Reference Consortium to trace how these regions differ and evolve.

They discovered 226 major centromere haplotypes—distinct genetic patterns—and 1,870 new genetic variants. By studying a four-generation family, they were able to follow centromeres as they changed from parent to child, tracking genetic changes across generations.

Quantum heat circuits learn electronics’ oldest trick: Sharing a power supply

Every electronic and optoelectronic device generates heat, and today that heat is managed almost entirely from the outside. Heatsinks, fans, cold plates and refrigerators are bulky exterior measures bolted onto a chip or package after the fact. They treat heat as a single averaged quantity to be removed in bulk, even though the heat is actually produced locally, component by component, deep inside the circuitry.

Quantum thermal devices offer a fundamentally different approach. Because they are tiny, heat-management circuitry can, in principle, be built right next to each electronic or optoelectronic component that needs it.

Instead of one bulk, averaged solution for an entire chip, each component could have its own tailored thermal circuit beside it, steering heat away exactly where it arises. That is the long-term technological promise motivating this field.

‘Lying mirror’ uses structured surfaces to conceal optical information

Mirrors normally reveal what is placed in front of them, even when their curvature distorts a reflection. Researchers at the University of California, Los Angeles (UCLA) have introduced a different optical concept: a “lying mirror” that hides information carried by an input image and transforms it into a misleading, ordinary-looking pattern at the output. The study is published in the journal Nature Communications.

The all-optical system combines a reflective mirror with an optimized structured diffractive surface. Instead of using a computer to digitally alter an image, the lying mirror performs the transformation through programmed light diffraction and passive light-matter interactions. Once the diffractive surface is designed and fabricated, the optical transformation that hides the input information requires no digital computation.

Real-time measurements reveal antiferromagnetic skyrmions move in line with an applied current

Skyrmions—essentially magnetic vortices—represent a promising approach in spintronics; in the future, they could serve as components in storage media or computers, potentially complementing established CMOS technologies. Researchers at Johannes Gutenberg University Mainz (JGU) have now visualized the interaction of antiferromagnetic skyrmions for the first time and shown that antiferromagnetic skyrmions move reproducibly along straight trajectories aligned with the driving electric current.

“Our results establish a quantitative framework for the interactions of antiferromagnetic skyrmions. In doing so, they pave the way for spintronic devices based on large numbers of skyrmions,” said Mona Bhukta from the research group of professor Mathias Kläui at the JGU Institute of Physics. The researchers published their findings today in the journal Nature Physics.

Could the Next Brain Interface Get Sprayed Up Your Nose?

A brain computer interface (BCI) is any technology that allows you to connect your 3 pounds of wetware to a computer. But instead of implanting electrodes via neurosurgery, might the next revolution in BCIs come from something very small, like nanoparticles? Would this allow us to spy on millions (or billions) of neurons talking at once — and could we do so without opening the skull? Will this allow BCI tech to become as common as smartphones? Join Eagleman as he talks with Tetiana Aleksandrova and Scott Meek from the company Subsense about why the next brain-computer interface might come from thinking small.

Subscribe for new episodes weekly. 🛎

INNER COSMOS PODCAST: Stanford neuroscientist David Eagleman tackles wild questions that illuminate new facets of our lives.
❤️ iHeartRadio: ihr.fm/3TxDAqb.
🍎 Apple podcasts: apple.co/3LTxTkH
📢 Amazon Music: amzn.to/3ZxGM6R
🟢 Spotify: spoti.fi/3lOaXZl.

X.com/davideagleman.
instagram.com/davideagleman.
fb.com/david.m.eagleman.
linkedin.com/in/davideagleman.

#Eagleman #InnerCosmos #Science #Neuroscience

Controlled cracking technique prints quantum dots into tiny pixels for sharper displays

Recent technological advances have enabled the development of increasingly sophisticated, sharper displays for electronic devices. Many modern displays use light-emitting diodes, or LEDs, tiny semiconductor-based components that emit light when an electrical current passes through them.

Quantum Heat Waves Spotted at Room Temperature for the First Time

The discovery could improve thermal management in electronics and support advances in quantum and next-generation computing technologies.

Heat usually spreads outward through a solid, making it difficult to control once it begins moving. Until now, a wavelike form of heat transport called phonon focusing had been observed only at extremely low, or cryogenic, temperatures, sharply limiting its study and possible applications.

Researchers at the UCLA Samueli School of Engineering have now shown that phonons, quantum vibrations that carry heat through a material, can travel along concentrated, ray-like paths at room temperature. Rather than dispersing evenly in every direction, the heat followed routes determined by the underlying crystal structure, suggesting a new way to direct thermal energy in future electronics and quantum technologies.