“This research marks the first time that we have been able to identify a specific chemical change that is unique to the development of Huntington’s disease, which opens the possibility of developing new tests to study the early changes of the disease before irreversible damage occurs.”
U.K. and German researchers are hopeful that their discovery of a key biochemical change involved in the development of Huntington’s disease could lead to its early detection and treatment.
On this day in 1992, the Vatican admitted that Galileo was correct in believing that the earth went around the sun.
2. In the first place, I wish to congratulate the Pontifical Academy of Sciences for having chosen to deal, in its plenary session, with a problem of great importance and great relevance today: the problem of ‘the emergence of complexity in mathematics, physics, chemistry and biology’
The emergence of the subject of complexity probably marks in the history of the natural sciences a stage as important as the stage which bears relation to the name of Galileo, when a univocal model of order seemed to be obvious. Complexity indicates precisely that, in order to account for the rich variety of reality, we must have recourse to a number of different models.
This realisation poses a question which concerns scientists, philosophers and theologians: how are we to reconcile the explanation of the world – beginning with the level of elementary entities and phenomena – with the recognition of the fact that ‘the whole is more than the sum of its parts’?
NASA plans to send crewed missions to Mars over the next decade—but the 140 million-mile (225 million-kilometer) journey to the red planet could take several months to years round trip.
This relatively long transit time is a result of the use of traditional chemical rocket fuel. An alternative technology to the chemically propelled rockets the agency develops now is called nuclear thermal propulsion, which uses nuclear fission and could one day power a rocket that makes the trip in just half the time.
Nuclear fission involves harvesting the incredible amount of energy released when an atom is split by a neutron. This reaction is known as a fission reaction. Fission technology is well established in power generation and nuclear-powered submarines, and its application to drive or power a rocket could one day give NASA a faster, more powerful alternative to chemically driven rockets.
In 2017, Jacob Haendel was living a normal life as a head chef in…
A paralysed man who had an extreme form of locked-in syndrome and heard a nurse say he was “brain dead” has become the first ever to recover after hearing medical professionals debating whether or not to switch off his life support.
In 2017, Jacob Haendel was living a normal life as a head chef in Boston, Massachusetts but in the space of a few weeks, his life was turned upside down after he was diagnosed with acute toxic progressive leukoencephalopathy, which progressed into locked-in syndrome and forced his body would slowly shut down. An extreme form of locked-in syndrome is a condition where a patient is aware but cannot move or communicate verbally due to complete paralysis and can be caused by brain trauma, infection or exposure to toxins.
It is not known exactly how Jacob developed the condition, though he says his life as a chef consuming certain chemicals “wilfully and otherwise” may have been a factor. He ended up paralysed, unable to talk or blink within a few months and, could hear hospital staff deliberating over switching off machines.
Haven’t heard from Bill Andrews in awhile.
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Here we talk with Dr Bill Andrews all about telomeres, why they are on the critical path of aging and finding a way to lengthen them is required in an complete longevity solution.
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⏲️Chapters.
00:00 Why telomeres.
07:10 Telomeres and aging.
14:36 Telomerase in stem cells.
20:15 BiOptimizers.
21:44 Telomere shortening.
23:25 Measuring telomere length.
25:30 Biological age.
30:30 Slowing telomere shortening.
39:30 Supplements to help.
41:30 Sierra Science Chemicals \& Gene therapy.
49:30 How is telomerase repressed.
56:10 Liz Parrish \& Gene therapy.
1:01:40 Gene therapy delivery.
1:09:20 Telomerase \& cancer.
1:17:00 Why aging.
1:20:30 Telomeres \& senescence.
1:24:30 More information.
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It is well-established that chronic MSK pain is the key factor for physical disability in the adult population. 19 The World Health Organization (WHO) estimates that 20–33% (over 1.71 billion individuals) of the global population suffers from chronic MSK pain. 20 This type of disorder is characterized by acute or chronic pain in MSK structures, which involve muscles, tendons, ligaments, bones, and nerves. 21 The most common conditions responsible for visits to a physician’s office are OA, rheumatoid arthritis, myofascial pain syndrome (MPS), and low back and neck pain. 22 Less common incidents are generally accompanying with injuries like of tendon sprains, ligament tears, muscle tears, fractures, and similar damage during sports. 20
If left untreated, these conditions progressively increase suffering, disability, and drug consumption, which subsequently diminish an individual’s quality of life. 23 This also translates to a main community health problem due to significant high expenses for health-care systems and insurance for disability. Advanced age may remain the top variable associated with the increased risk of musculoskeletal disorders (MSDs) and MSK pain; however, these conditions may still unfold at any given age for various reasons. Therefore, every individual is at risk of experiencing MSK pain throughout an entire lifetime. 24 Acute pain can become chronic due to numerous factors. The level of intensity, site, and time of noxious stimuli are dictated by the interplay between mechanical, chemical, and thermal receptors and immune cells. 25 Under standard conditions, noxious stimuli and painful sensations gradually decrease with the progression of healing.
Imagine owning a camera so powerful it can take freeze-frame photographs of a moving electron – an object traveling so fast it could circle the Earth many times in a second. Researchers at the University of Arizona have developed the world’s fastest electron microscope that can do just that.
They believe their work will lead to groundbreaking advancements in physics, chemistry, bioengineering, materials sciences and more.
“When you get the latest version of a smartphone, it comes with a better camera,” said Mohammed Hassan, associate professor of physics and optical sciences. “This transmission electron microscope is like a very powerful camera in the latest version of smartphones; it allows us to take pictures of things we were not able to see before – like electrons. With this microscope, we hope the scientific community can understand the quantum physics behind how an electron behaves and how an electron moves.”