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Understanding complex biological and biomedical systems is greatly aided by 3D imaging, which provides much more detailed information than traditional two-dimensional methods. However, live cell and tissue imaging remain challenging due to factors like limited imaging speed and significant scattering in turbid environments.

In this context, multimodal microscopy techniques are notable. Specifically, nonlinear techniques like CRS (coherent Raman scattering) use optical vibrational spectroscopy, providing precise chemical imaging in tissues and cells in a label-free way.

Furthermore, stimulated Raman scattering (SRS) microscopy, a CRS method, can accurately capture images of biomolecules due to the linear relationship between stimulated Raman intensity and the concentration of target molecules. It does so with high sensitivity and without interference from unwanted nonresonant backgrounds.

At approximately 18:17 CET (17:17 UTC) on Wednesday, February 21, 2024, ESA’s ERS-2 satellite completed its atmospheric reentry over the North Pacific Ocean. No damage to property has been reported.

ESA’s second European Remote Sensing satellite, ERS-2, was launched almost 30 years ago, on April 21, 1995. Together with the almost-identical ERS-1, it provided invaluable long-term data on Earth’s land surfaces, ocean temperatures, ozone layer, and polar ice extent that revolutionized our understanding of the Earth system. It was also called upon to monitor and assist the response to natural disasters.

“The ERS satellites have provided a stream of data which has changed our view of the world in which we live,” said ESA’s Director of Earth Observation Programmes, Simonetta Cheli. “They have provided us with new insights on our planet, the chemistry of our atmosphere, the behavior of our oceans, and the effects of mankind’s activity on our environment – creating new opportunities for scientific research and applications.”

For years, researchers have dedicated themselves to developing methods that can effectively and economically break down plant materials, enabling their transformation into valuable bioproducts that enhance our daily lives.

Bio-based fuels, detergents, nutritional supplements, and even plastics are the result of this work. And while scientists have found ways to degrade plants to the extent needed to produce a range of products, certain polymers such as lignin, which is a primary ingredient in the cell wall of plants, remain incredibly difficult to affordably break down without adding pollutants back into the environment. These polymers can be left behind as waste products with no further use.

A specialized microbial community composed of fungus, leafcutter ants, and bacteria is known to naturally degrade plants, turning them into nutrients and other components that are absorbed and used by surrounding organisms and systems. But identifying all components and biochemical reactions needed for the process remained a significant challenge—until now.

In this first article in a series on philosophy and science, we take a look at materialism and why it is fundamental to science.

A short disclaimer before we read further: I’m a materialist. Materialism is a branch of philosophy to which the sciences, particularly the physical and life sciences, owe a lot. Materialism posits that the material world — matter — exists, and everything in the Universe, including consciousness, is made from or is a product of matter. An objective reality exists and we can understand it. Without materialism, physics, chemistry, and biology as we know it wouldn’t exist.

Another branch of philosophy, idealism, is in direct contradiction to materialism. Idealism states that, instead of matter, the mind and consciousness are fundamental to reality; that they are immaterial and therefore independent of the material world.

Injuries in the central nervous system heal poorly because cavities scar. Researchers hope to remedy this problem by filling the cavities in such a way that stem cells feel comfortable in them.

Researchers from Bochum and Dortmund have created an artificial cell environment that could promote the regeneration of nerves. Usually, injuries to the brain or spinal cord don’t heal easily due to the formation of fluid-filled cavities and scars that prevent tissue regeneration. One starting point for medical research is therefore to fill the cavities with a substance that offers neural stem cells optimal conditions for proliferation and differentiation. The team from Ruhr University Bochum and TU Dortmund University, both in Germany, showed that positively charged hydrogels can promote the survival and growth of stem cells.

Dr. Kristin Glotzbach and Professor Andreas Faissner from the Department of Cell Morphology and Molecular Neurobiology in Bochum cooperated with Professor Ralf Weberskirch and Dr. Nils Stamm from the Faculty of Chemistry and Chemical Biology at TU Dortmund University. The team describes the findings in the American Chemical Society Journal Biomaterials Science and Engineering from January 16, 2024.

Hidden beneath the heavily cratered surface of Mimas, one of Saturn’s smallest moons lies a secret: a global ocean of liquid water. This astonishing discovery, led by Dr. Valéry Lainey of the Observatoire de Paris-PSL and published in the journal Nature, reveals a “young” ocean formed just 5 to 15 million years ago, making Mimas a prime target for studying the origins of life in our solar system.

“Mimas is a small moon, only about 400 kilometers in diameter, and its heavily cratered surface gave no hint of the hidden ocean beneath,” says Dr. Nick Cooper, a co-author of the study and Honorary Research Fellow in the Astronomy Unit of the School of Physical and Chemical Sciences at Queen Mary University of London.

“This discovery adds Mimas to an exclusive club of moons with internal oceans, including Enceladus and Europa, but with a unique difference: its ocean is remarkably young, estimated to be only 5 to 15 million years old.”

As interest in wearable technology has surged, research into creating energy-storage devices that can be woven into textiles has also increased. Researchers at North Carolina State University have now identified a “sweet spot” at which the length of a threadlike energy storage technology called a “yarn-shaped supercapacitor” (YSC) yields the highest and most efficient flow of energy per unit length.

“When it comes to the length of the YSC, it’s a tradeoff between power and energy,” said Wei Gao, corresponding author of a paper on the work and an associate professor of textile engineering, chemistry and science at NC State.

“It’s not only about how much energy you can store, but also the internal resistance we care about.”

Science Fiction has long contemplated the idea that alien life not based on carbon chemistry such as silicon might exist on distant and strange worlds, or might be made to exist advanced biological engineering. What would such life be like?

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