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Archive for the ‘biotech/medical’ category: Page 889

Sep 30, 2022

‘Love Hormone’ Oxytocin Could Mend a Broken Heart

Posted by in categories: biotech/medical, health, sex

Summary: Oxytocin, a hormone connected with bonding and love, could help to heal damage following a heart attack. Researchers found oxytocin stimulates stem cells from the heart’s outer layer and migrates into the middle layer where it develops into muscle cells that generate heart contractions. This could be used to promote the regeneration of heart cells following a heart attack.

Source: Frontiers.

The neurohormone oxytocin is well-known for promoting social bonds and generating pleasurable feelings, for example from art, exercise, or sex. But the hormone has many other functions, such as the regulation of lactation and uterine contractions in females, and the regulation of ejaculation, sperm transport, and testosterone production in males.

Sep 30, 2022

The compositional and functional diversity of the gut fungal microbiome

Posted by in categories: biotech/medical, health

In a recent study published in The Lancet Microbe, researchers assessed the role of gut bacterial microbiome assembly and the gut mycobiome in relation to health, pathology, and clinical applications.

Studies have built a framework for investigating how gut fungi are connected to—or perhaps cause—different diseases and how to alter gut fungi to treat diseases by revealing the landscape of gut mycobiome composition in humans. Importantly, available mycobiome discoveries are not extensively applied to clinical practice, and gut fungi are still widely ignored in the context of treatments based on the microbiota.

According to studies conducted on mice, altering the intestinal fungi through oral administration of antifungal medications worsened allergic rhinitis and colitis, indicating that an imbalance in the gut mycobiome may play a role in the pathogenesis of intestinal as well as extra-intestinal diseases. Similar comparisons between the gut mycobiomes of healthy people and patients with various intestinal and extra-intestinal disorders have been documented in many studies.

Sep 30, 2022

Mouse study suggests genetics of longevity are influenced by both gender and age

Posted by in categories: biotech/medical, genetics, life extension

A team of researchers affiliated with several institutions in Switzerland and the U.S. reports evidence that the genetics of longevity are influenced by both gender and age. In their paper published in the journal Science, the group describes their study of aging in mice and humans. João Pedro de Magalhães, with the University of Birmingham, has published a Perspective piece in the same journal issue outlining the technical challenges to understanding how aging works and the work done by the team on this new effort.

Scientists have been studying the for many years but still do not have a good explanation for why organisms age and why some live longer than others. In this new effort, the researchers wondered if something in the genome plays a role in how long a species lives on average.

Noting that another team had created a very large dataset of information regarding aging in nearly 3,000 mice, the researchers found that it also contained . After obtaining access to the database, they analyzed that genetic information—more specifically, they conducted quantitative trait locus mapping. They found multiple loci that they could associate with longevity, some that were specific to one or the other gender. They also found that mice who weighed more during their early years or who had small litter sizes tended to die younger. They suggest the same that were associated with aging may have also played a role in the other two traits. The researchers also found that the aging-related genes they isolated appeared to remain dormant until the latter stages of a given individual’s life.

Sep 30, 2022

Viral infections including COVID are among the important causes of dementia. One more reason to consider vaccination

Posted by in categories: biotech/medical, life extension, neuroscience

With more of us living into old age than at any other time, dementia is increasing steadily worldwide, with major individual, family, societal and economic consequences.

Treatment remains largely ineffective and aspects of the underlying pathophysiology are still unclear. But there is good evidence that —and their manifestation as dementia—are not an inevitable consequence of aging.

Many causes of dementia, including viral infections, are preventable.

Sep 30, 2022

New study shows transmission of epigenetic memory across multiple generations

Posted by in categories: biotech/medical, genetics, health

Without altering the genetic code in the DNA, epigenetic modifications can change how genes are expressed, affecting an organism’s health and development. The once radical idea that such changes in gene expression can be inherited now has a growing body of evidence behind it, but the mechanisms involved remain poorly understood.

A new study by researchers at UC Santa Cruz shows how a common type of epigenetic modification can be transmitted via sperm not only from parents to offspring, but to the next generation (“grandoffspring”) as well. This is called “transgenerational epigenetic inheritance,” and it may explain how a person’s health and development could be influenced by the experiences of his or her parents and grandparents.

The study, published the week of September 26 in the Proceedings of the National Academy of Sciences (PNAS), focused on a particular modification of a histone protein that changes the way DNA is packaged in the chromosomes. This widely studied epigenetic mark (called H3K27me3) is known to turn off or “repress” the affected genes and is found in all multicellular animals—from humans to the nematode worm C. elegans used in this study.

Sep 30, 2022

Stretchy, bio-inspired synaptic transistor can enhance or weaken device memories

Posted by in categories: biotech/medical, robotics/AI, wearables

Robotics and wearable devices might soon get a little smarter with the addition of a stretchy, wearable synaptic transistor developed by Penn State engineers. The device works like neurons in the brain to send signals to some cells and inhibit others in order to enhance and weaken the devices’ memories.

Led by Cunjiang Yu, Dorothy Quiggle Career Development Associate Professor of Engineering Science and Mechanics and associate professor of biomedical engineering and of and engineering, the team designed the synaptic transistor to be integrated in robots or wearables and use to optimize functions. The details were published Sept. 29 in Nature Electronics.

“Mirroring the human brain, robots and using the synaptic transistor can use its to ‘learn’ and adapt their behaviors,” Yu said. “For example, if we burn our hand on a stove, it hurts, and we know to avoid touching it next time. The same results will be possible for devices that use the synaptic transistor, as the artificial intelligence is able to ‘learn’ and adapt to its environment.”

Sep 30, 2022

Alzheimer’s drug study yields positive results, say makers Eisai and Biogen

Posted by in categories: biotech/medical, neuroscience

Sept 27 (Reuters) — An experimental Alzheimer’s drug made by Eisai Co Ltd (4523.T) and Biogen (BIIB.O) slowed cognitive and functional decline in a large trial of patients in the early stages of the disease, they said on Tuesday, potentially a rare win in a field littered with failed drugs.

Multiple drugmakers have so far tried and failed to find an effective treatment for the brain-wasting disease that affects about 55 million people globally. A breakthrough would be a major boost to similar studies being run by Roche and Eli Lilly.

Speaking of the Eisai-Biogen drug results announced late on Tuesday night, Ronald Petersen, director of the Mayo Clinic Alzheimer’s Disease Research Center in Rochester, Minnesota said: “It’s not a huge effect, but it’s a positive effect”.

Sep 30, 2022

Researchers capture first images of carbon dioxide emissions from commercial aircraft engine

Posted by in categories: biotech/medical, chemistry

Researchers have used a novel near-infrared light imaging technique to capture the first cross-sectional images of carbon dioxide in the exhaust plume of a commercial jet engine. This new state-of-the-art technology could help accelerate turbine combustion research aimed at developing engines and aviation fuels that are more environmentally friendly.

“This approach, which we call chemical species tomography, provides spatially resolved information for from a large-scale commercial engine,” said research team leader Michael Lengden from the University of Strathclyde in the U.K. “This information has not been available before at this industrial scale and is a big improvement over the current industry-standard emissions measurement, which involves taking gas from the exhaust to a gas analyzer system in a different location.”

The researchers report the new research in Applied Optics. Chemical species tomography works much like the X-ray-based CT scans used in medicine, except that it uses near-infrared laser light tuned to the absorption wavelength of a target molecule and requires very fast imaging speeds to capture the dynamic processes of combustion.

Sep 30, 2022

‘Love hormone’ is revealed to have heart healing properties

Posted by in categories: biotech/medical, engineering, health, sex

The neurohormone oxytocin is well-known for promoting social bonds and generating pleasurable feelings, for example from art, exercise, or sex. But the hormone has many other functions, such as the regulation of lactation and uterine contractions in females, and the regulation of ejaculation, sperm transport, and testosterone production in males.

Now, researchers from Michigan State University show that in zebrafish and human cell cultures, oxytocin has yet another unsuspected function: It stimulates derived from the heart’s outer layer (epicardium) to migrate into its middle layer (myocardium) and there develop into cardiomyocytes, that generate heart contractions. This discovery could one day be used to promote the regeneration of the human heart after a . The results are published in Frontiers in Cell and Developmental Biology.

“Here we show that oxytocin, a neuropeptide also known as the love hormone, is capable of activating heart repair mechanisms in injured hearts in zebrafish and human cell cultures, opening the door to potential new therapies for heart regeneration in humans,” said Dr. Aitor Aguirre, an assistant professor at the Department of Biomedical Engineering of Michigan State University, and the study’s senior author.

Sep 30, 2022

New alternative to LASIK growing in popularity as many ditch lenses

Posted by in category: biotech/medical

PHILADELPHIA (CBS) — A newly approved permanent contact lens is growing in popularity, it’s a new alternative for LASIK. No more fumbling with contacts or glasses, now there’s an FDA-approved lens that stays in place, and people say it’s life-changing.

This is the newest implantable contact lens, called EVO.

“It’s absolutely mind-blowing,” patient Rusell Joy said.

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