Lifeboat Foundation

A pill’s active ingredient can be absorbed quickly or slowly depending upon your body posture after taking it.

Corneal blindness occurs when the transparent membrane that covers the front of the eye and acts as a lens becomes opaque and prevents the light from reaching the back of the eye, inhibiting vision. It can be solved with a transplant, but experts estimate that 12.7 million people are currently waiting for a cornea donation. These membranes are in short supply: for every 70 that are needed, only one is available. In view of this problem, especially in countries where there are fewer donations of human corneas due to limited infrastructure, a group of Swedish researchers tested corneas made from pig skin collagen in 20 people who needed transplants (all of them Iranian or Indian citizens; 14 of them were blind). After two years, they all showed improvement, and those who were blind could see again. Although more complex clinical trials are still necessary to validate the measure, the first test of this bioengineered corneal tissue has proven to be safe. The results of this pilot study were published in the Nature Biotechnology journal.

There is also a socioeconomic aspect to corneal blindness: one million new cases are diagnosed every year, but according to researchers, most are concentrated in low-and middle-income countries in Asia, Africa and the Middle East – precisely where it is most difficult to obtain a donated human cornea, due to endless “economic, cultural, technological, political and ethical barriers.” Finding an alternative to the human cornea transplant is key, the authors point out, to fighting keratoconus, a disease that weakens and thins the cornea, and which is the reason for most transplants.

In order to find an alternative to donated human cornea, the researchers bioengineered collagen, the main protein in the human cornea, as a raw material. “For an abundant yet sustainable and cost-effective supply of collagen, we used medical-grade collagen sourced from porcine skin, a purified byproduct from the food industry already used in FDA-approved medical devices for glaucoma surgery and as a wound dressing,” they explain in the article. Unlike the human corneas, which must be used in less than two weeks, bioengineered corneas can be stored for up to two years.

NIA-funded researchers identified areas of the genome responsible for accelerating or slowing down brain aging.

While the OPD has been thrown open to the people, work is going on war footing as PM Modi is expected to inaugurate the hospital early next month. The hospital already has 25 transport ventilators from the PM CARES fund.

Any person coming for treatment will only have to pay Rs 10 in registration charges for a lifetime and there are nominal charges for treatment.

AIIMS Bilaspur is set up with the objectives of correcting regional imbalances in the availability of affordable/reliable tertiary healthcare services and also to augment facilities for quality medical education in the country.

When some materials are cooled to a certain temperature, they lose electric resistance, becoming superconductors.

In this state, an electric charge can course through the material indefinitely, making superconductors a valuable resource for transmitting high volumes of electricity and other applications. Superconductors ferry electricity between Long Island and Manhattan. They’re used in medical imaging devices such as MRI machines, in particle accelerators and in magnets such as those used in maglev trains. Even unexpected materials, such as certain ceramic materials, can become superconductors when cooled sufficiently.

But scientists previously have not understood what occurs in a material to make it a superconductor. Specifically, how high-temperature superconductivity, which occurs in some copper-oxide materials, works hasn’t been previously understood. A 1966 theory examining a different type of superconductors posited that electrons which spin in opposite directions bind together to form what’s called a Cooper pair and allow electric current to pass through the material freely.

Scientists in the Netherlands combined a functional MRI scanner with a powerful AI algorithm to reconstruct visual stimuli.

In a new medical breakthrough, scientists have successfully grown a synthetic embryo of a mouse without male sperm and a female womb. They used stem cells from mice to recreate the first stage of life and successfully developed an embryo with a brain, beating heart, and vitals for other organs.

The natural process of life was mimicked in the lab without eggs or sperm but with the body’s master cells, which can develop into almost any cell type in the body. The embryo was developed 8 ½ days after fertilization, containing the same structures as a natural one.

The study published in the journal Nature states that their result demonstrates the self-organization ability of embryonic and two types of extra-embryonic stem cells to reconstitute mammalian development. The researchers induced expression of a particular set of genes and established a unique environment for their interactions and got the stem cells to ‘talk’ to each other.

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In the Existential Hope-podcast (https://www.existentialhope.com), we invite scientists to speak about long-termism. Each month, we drop a podcast episode where we interview a visionary scientist to discuss the science and technology that can accelerate humanity towards desirable outcomes.

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Small devices letting patients collect diagnostics quality blood samples at home were getting lots of publicity in the past few months, as they are finding their way into clinical trials and are available as direct-to-consumer products. We asked Dr Erwin Berthier, CTO and Co-Founder of Tasso about the technology.

You can read the exclusive interview on our Patreon page. Thank you for your support!

https://www.patreon.com/posts/70639361