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There are around 42,900 new bowel cancer cases in the UK every year Experts have hailed “remarkable” new research which shows that giving chemotherapy before surgery for early-stage bowel cancer cuts the chance of the disease coming back by 28%. The study, funded by Cancer Research UK, suggests at least 5,000 patients in the UK every year could benefit from a tweak to how they receive chemotherapy.

Researchers from the Andrew and Erna Viterbi Faculty of Electrical and Computer Engineering at the Technion—Israel Institute of Technology have presented the first experimental observation of Cherenkov radiation confined in two dimensions. The results represent a new record in electron-radiation coupling strength, revealing the quantum properties of the radiation.

Cherenkov radiation is a unique physical phenomenon, which for many years has been used in medical imaging and in particle detection applications, as well as in laser-driven electron accelerators. The breakthrough achieved by the Technion researchers links this phenomenon to future photonic quantum computing applications and free-electron quantum light sources.

The study, which was published in Physical Review X, was headed by Ph.D. students Yuval Adiv and Shai Tsesses from the Technion, together with Hao Hu from the Nanyang Technological University in Singapore (today professor at Nanjing university in China). It was supervised by Prof. Ido Kaminer and Prof. Guy Bartal of the Technion, in collaboration with colleagues from China: Prof. Hongsheng Chen, and Prof. Xiao Lin from Zhejiang University.

The horrors of HBO’s latest hit are based on real-world nightmares. Here’s what a Cordyceps apocalypse might look like in reality.

Talk Title: Human Age Reversal through Mitochondrial Transplantation.

Tom Benson, CEO at Mitrix Bio, presents at Investing in the Age of Longevity 2022. In his talk, Tom outlines the effect of mitochondria on aging, and how mitochondrial transplantation can be used for age reversal. Showcasing how Mitrix Bio is pioneering the application of this technique, Tom also presents the company’s roadmap for clinical trials and commercialisation of its platform.

Continue reading “Investing in the Age of Longevity 2022 — Tom Benson — Mitrix Bio” »

Our ability to learn, move, and sense our world comes from the neurons in our brain. This information moves through our brain between neurons that are linked together by tens of trillions of tiny structures called synapses. Although tiny, synapses are not simple and must be precisely organized to function properly. Indeed, diseases like autism and Alzheimer’s are increasingly linked to defects in the organization and number of these tiny structures. Now researchers at Thomas Jefferson University have found a new way in which synapses organization is controlled, which could eventually lead to better treatments for neurological diseases.

Researchers who study how synapses grow and are lost have long focused on a molecule called PSD-95, which helps create and maintain the scaffolding around which a synapse is built. A new paper, publishing in Nature Neuroscience October 19th, reveals that a second protein interacts with PSD-95 and enables adaptive changes, such as changes in sensation, to be translated into changes in the synaptic scaffold, changing the amount of PSD-95 at the synapse.

“We can’t see or learn or talk without synapses working properly,” says senior author Matthew Dalva, Ph.D., Associate Professor of Neuroscience at the Sidney Kimmel Medical College at Thomas Jefferson University and the Farber Institute of Neuroscience at Jefferson and leader of the Theme Team for Synapse Biology. “We need a better understanding of how the brain works normally in order to develop a better sense of where to intervene to stop or cure diseases of the brain. It’s important to understand how these molecules interact.”

Computers and information technologies were once hailed as a revolution in education. Their benefits are undeniable. They can provide students with far more information than a mere textbook. They can make educational resources more flexible, tailored to individual needs, and they can render interactions between students, parents, and teachers fast and convenient. And what would schools have done during the pandemic lockdowns without video conferencing?

The advent of AI chatbots and large language models such as OpenAI’s ChatGPT, launched last November, create even more new opportunities. They can give students practice questions and answers as well as feedback, and assess their work, lightening the load on teachers. Their interactive nature is more motivating to students than the imprecise and often confusing information dumps elicited by Google searches, and they can address specific questions.

The algorithm has no sense that “love” and “embrace” are semantically related.

Twenty years ago, following the initial sequencing of the human genome, geneticists started carrying out extensive genome-wide association studies to find genomic regions connected to human disease.

In addition to the DNA sequence, another stable level of molecular data created during development called epigenetic modifications also plays a role in disease risk.

Researchers have been examining these epigenetic changes for more than ten years to look for links to disease. More than a thousand of these epigenome-wide association studies have been published as of late.

In this Review, Villeda and colleagues describe blood-to-brain communication from a systems physiology perspective, with an emphasis on blood-derived signals as potent drivers of both age-related brain dysfunction and brain rejuvenation.

Key Points. FMT from young mice restored lymphoid differentiative potential and improved the number and engraftment ability of aged HSCs. Lachnospiraceae and try.