Tissue processing advance can label proteins at the level of individual cells across whole, intact rodent brains and other large samples just as fast and uniformly as in dissociated single cells.
Category: biotech/medical – Page 352
Scientists Just Found a Way to Starve Cancer Using Fat Cells
Scientists at UC San Francisco have pioneered a groundbreaking approach to fighting cancer using engineered fat cells.
By transforming ordinary fat into high-energy beige fat using CRISPR, they created a cell type that voraciously consumes nutrients — outcompeting and starving tumors.
Revolutionizing cancer treatment: engineered fat cells starve tumors.
Michio Kaku has some news about simulation theory
Sorry, you’re not Neo and this isn’t “The Matrix.” Michio Kaku gets real about simulation theory.
Up next, Is reality real? These neuroscientists don’t think so ► https://youtu.be/RZdfE_7cde0?si=2-isNPeC1lVvgbiu.
Are we all just living in an elaborate simulation?
After movies like “The Matrix” (1999) posited the existence of a superficial world layered over our own, human imagination has run abound with theories about the nature of our reality. To a small but passionate minority, the red pill that can awaken us to this illusion is right at our fingertips.
World-renowned physicist Michio Kaku isn’t quite ready to take that pill. In fact, he’s skeptical that the pills even exist. He explains why.
Go Deeper with Big Think:
Lung cancer in people who have never smoked on the rise — with research pointing to one common cause
The proportion of people who have never smoked being diagnosed with lung cancer is rising, with new research pointing to air pollution as a growing contributor to lung cancer around the world.
Researchers from the International Agency for Research on Cancer said for never-smokers, lung cancer was the fifth largest leading cause of cancer deaths worldwide. Those cases were nearly exclusively the subtype adenocarcinoma — a tumour that forms in the glandular tissue — and largely in women and Asian populations.
The research, published in The Lancet Respiratory Medicine journal, found nearly 200,000 or about 15 per cent of all adenocarcinoma cases in 2022 were a result of air pollution, suggesting the risk of lung cancer linked to air pollution was also on the rise, particularly in east Asia and China.
Role of Macrophage lncRNAs in Mediating Inflammatory Processes in Atherosclerosis and Sepsis
Long noncoding RNAs (lncRNAs) are molecules 200 bases in length without protein-coding functions implicated in signal transduction and gene expression regulation via interaction with proteins or RNAs, exhibiting various functions. The expression of lncRNAs has been detected in many cell types, including macrophages, a type of immune cell involved in acute and chronic inflammation, removal of dead or damaged cells, and tissue repair. Increasing evidence indicates that lncRNAs play essential roles in macrophage functions and disease development. Additionally, many animal studies have reported that blockage or modulation of lncRNA functions alleviates disease severity or morbidity rate.
Proposal for Enhancing Experimental Anti-aging Treatment with Young Plasma
Josh Mitteldorf suggests new protocol for experimental young plasma therapy.
Scientists explore concentrated plasma infusions for stronger anti-ageing effects.
01-Feb-2025Key points from article :
Scientists have long observed the remarkable rejuvenation effects of young plasma in ageing rats, but translating these findings into human therapies has been slow due to intellectual property barriers and funding challenges. In the meantime, a niche industry has emerged in Texas, where ageing individuals can receive plasma infusions from young donors for tens of thousands of dollars. However, these treatments, which replace about 35% of a patient’s plasma, fall short of the dramatic regeneration seen in laboratory animals. Researchers suspect that the exosome dosages in these human procedures are too low to match the full rejuvenation potential seen in rats.
To address this, a new approach suggests concentrating young plasma by removing excess water, allowing for higher doses without overloading the circulatory system. Freeze-drying plasma, a long-standing technology, could be adapted to reconstitute plasma at three or more times its normal strength. However, modifications would be necessary—such as removing platelets to avoid clotting risks and adjusting albumin levels for safety.
A key question remains: Can young exosomes permanently reprogram the body’s ageing process, or will ongoing infusions be required? If the body starts producing its own youthful exosomes after treatment, the therapy could be a game-changer. If not, frequent infusions might be necessary, making the procedure less practical. While uncertainty remains, results from animal studies provide hope that young plasma could lead to longer-lasting rejuvenation in humans.
New Nanotech Bandages Kill Bacteria and Speed Up Healing
Researchers have developed nanoflower-coated bandages with antibiotic and anti-inflammatory properties, capable of killing bacteria and promoting wound healing.
A carnation-like nanostructure could one day be used in bandages to promote wound healing. Researchers report in ACS Applied Bio Materials that laboratory tests of their nanoflower-coated dressings demonstrate antibiotic, anti-inflammatory, and biocompatible properties.
They state that these results indicate tannic acid and copper(II) phosphate sprouted nanoflower bandages are promising candidates for treating infections and inflammatory conditions.
Thousands of tiny, time-aware sensors can collectively map chemical concentrations within narrow tubes
When synthesizing chemicals, stationary sensors can collect and communicate detailed data from within a reactor system. Physically installed sensors reach their limitations when it comes to mapping concentrations within a fluid flowing through hard-to-reach areas—particularly within long, narrow tubes.
While sensors can be placed on the reactor’s perimeter in an industrial setting, suspending sensors in the center of a pipe would disrupt flow. In a medical application, such as mapping chemical concentrations within the intestines to pinpoint internal bleeding, implanted sensors become impractical.
A new framework optimizes the use of time-aware particulate sensors (TAPS)—a tiny sensor that travels through the system and remembers when it encounters a target chemical—to map these uncharted areas.
Researchers use unconventional method to help solve issue plaguing crops around the world: ‘Our research [has] remarkable potential’
New genetic research from the University of Florida may help make key crops such as potatoes, tomatoes, and peppers more resistant to disease and environmentally resilient as well as increase their nutritional value.
“Our research illustrates the remarkable potential of combining deep taxonomic expertise with cutting-edge biotechnology,” author Fabio Pasin told the Chinese Academy of Sciences, via Phys.org. “By focusing on the Solanaceae family, we can enhance not only widely recognized crops but also bring underutilized species into the agricultural mainstream, improving food security and enriching nutritional diversity across the globe.”
Researchers used recombinant virus technologies to give new breeds of plants particular traits. This method is very specific about promoting certain traits in new breeds. Scary as it might sound to use an engineered virus to change the DNA of our food, it’s a way of improving biodiversity in agriculture when farming has become more and more homogeneous and thus vulnerable.
What’s Beyond The Observable Universe?
Hi Spacecats, I’m Dr Maggie Lieu and welcome to my channel, where you can find all things space, astronomy and physics! Ever wondered what’s beyond the observable universe? This video explains the concept of the observable universe, the expansion of space, and explores theories about what might lie beyond, from infinite space to the multiverse.
Media credits:
galaxies: ESA/Hubble/DSS/Risinger.
Expansion Universe: Kornmesser/Calcada/NASA/ESA/Hubble.
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