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High-definition organic LED microdisplays with reduced electrical crosstalk could enhance VR and AR experiences

Researchers at the University of Liège (Belgium) have uncovered a previously unknown mechanism that regulates the immune response against parasites. During a parasitic infection, specific immune cells, known as virtual memory T cells, become activated and express a surface molecule called CD22, which prevents an excessive immune reaction. This discovery could help in better-controlling inflammation and improving immune responses to infections.

The findings are published in the journal Science Immunology.

Nearly a quarter of the world’s population is infected by helminths, that establish themselves in the intestine for extended periods. In response to these invaders, the immune system deploys complex defense strategies. In their recent study, the researchers revealed a previously unsuspected mechanism that regulates the activation of certain : CD8+ virtual memory T cells (TVM).

Biocomputers made from human brain cells could run the AI systems of the future

Today’s computers use vast amounts of energy to do tasks that a living brain can achieve much more efficiently. So scientists are trying to create organic computers that can function at low energy levels.

A start-up on the shores of Lake Geneva is building computer networks using human brain cells, which could transform Artificial Intelligence systems.

It’s the latest foray into the field of ‘bio-computing’, also known as wetware.

RAZOR’s Amelia Hemphill visits the FinalSpark lab in Switzerland to find out more about how the brain organoids are grown and trained.

Each organoid is made up of about 10,000 neurons, or brain nerve cells grown from stem cells. These small spheres, approximately 0.5mm in diameter, are kept alive in incubators at near body temperature. They are then connected to tiny electrodes allowing for communication and training.

Outside-In Signaling Shows a Route Into Cancer Cells

A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism that could be exploited for delivering other drugs.

Many malignant cancers overexpress a protein called P-cadherin, which is embedded in the cell membrane. Because cancer cells have a lot of P-cadherin sticking out of their surface, the protein has been targeted for drug development.

Monoclonal antibodies against P-cadherin can carry a drug payload to the cancer cells. It has not been clear, though, exactly how the antibodies attach to P-cadherin or how they get inside the cancer cell once attached.

Artemisia herba-alba: Scientists Have Discovered That a Common Herb Could Help Treat Colon Cancer

Researchers have found that Artemisia herba-alba, a medicinal herb, contains compounds capable of fighting colorectal cancer. The plant extract halted cancer cell growth, disrupted key pathways, and showed potential as a less harmful alternative to chemotherapy.

Scientists from the University of Sharjah have discovered that Artemisia herba-alba, a naturally occurring aromatic herb, contains compounds with potential therapeutic effects against colorectal cancer.

This herb, commonly known as common wormwood, white wormwood, or herba alba, grows naturally in North Africa and the Middle East, where it has long been used in traditional medicine. Local populations have historically relied on it to treat conditions such as bronchitis, diarrhea, hypertension, and diabetes.

This Experiment Promised Immortality, The Result Was Horrific

Some people will do anything to live forever: injecting young blood, freezing their heads, even zapping themselves with electricity in places you’d rather not imagine. On today’s episode of The Infographics Show, we’re diving into the strangest and most extreme attempts to cheat death, and why they might make you rethink wanting to live forever!

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Brain Cells Use Muscle-Like Signals to Strengthen Learning and Memory

Summary: New research reveals that brain cells use a muscle-like signaling mechanism to relay information over long distances. Scientists discovered that dendrites, the branch-like extensions of neurons, contain a structured network of contact sites that amplify calcium signals—similar to how muscles contract. These contact sites regulate calcium release, activating key proteins involved in learning and memory.

This mechanism explains how neurons process information received at specific points and relay it to the cell body. Understanding this process sheds light on synaptic plasticity, which underlies learning and memory formation. The findings could provide new insights into neurodegenerative diseases like Alzheimer’s.

Nerve cells optimize energy by controlling mRNA and protein distribution, study finds

Nerve cells have amazing strategies to save energy and still perform the most important of their tasks. Researchers from the University Hospital Bonn (UKB) and the University of Bonn as well as the University Medical Center Göttingen found that the neuronal energy conservation program determines the location and number of messenger RNA (mRNA) and proteins and differs depending on the length, longevity and other properties of the respective molecule. The work has now been published in Nature Communications.

We have all experienced the need to save energy in recent years. To do this, we all had to come up with strategies to save energy while still meeting our most important needs.

Our are facing a similar dilemma: They have to supply their synapses, i.e., their contact points with other neurons, but also organize their in such a way that they don’t produce too much or too little proteins.

The spliceosome: An atomic-level look into how cells avoid errors when manufacturing mRNA

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a basic requirement for producing proteins that fulfill an organism’s vital functions. Faulty functioning of a spliceosome can lead to a variety of serious diseases.

Researchers at the Heidelberg University Biochemistry Center (BZH) have succeeded for the first time in depicting a faulty “blocked” at high resolution and reconstructing how it is recognized and eliminated in the cell. The research was published in Nature Structural & Molecular Biology.

The of all living organisms is contained in DNA, with the majority of genes in higher organisms being structured in a mosaic-like manner. So the cells are able to “read” the instructions for building proteins stored in these genetic mosaic particles, they are first copied into precursors of mRNA, or messenger RNA. The spliceosome then converts them into mature, functional mRNA.